You are not logged in

Dataset Description

Dataset: RELA (p65) ChIP-PET Binding Sites (OREGDS00012) Description: NF-kappaB is a key mediator of inflammation. In this study, using ChIP-PET technology, the genome-wide loci bound by the RELA subunit of NF-kappaB in lipopolysaccharide (LPS)-stimulated human monocytic cells are mapped, and together with global gene expression profiling, an overrepresentation of the E2F1-binding motif among RELA-bound loci associated with NF-kappaB target genes is found. Dataset URL: http://www.molecule.org/cgi/content/full/27/4/622/DC1/ Citation Information: Ching-Aeng Lim, Fei Yao, Joyce Jing-Yi Wong, Joshy George, Han Xu, Kuo Ping Chiu, Wing-Kin Sung, Leonard Lipovich, Vinsensius B. Vega, Joanne Chen, Atif Shahab, Xiao Dong Zhao, Martin Hibberd, Chia-Lin Wei, Bing Lim, Huck-Hui Ng, Yijun Ruan, and Keh-Chuang Chin. 2007. Genome-wide Mapping of RELA(p65) Binding Identifies E2F1 as a Transcriptional Activator Recruited by NF-kappaB upon TLR4 Activation. Molecular Cell. 27:622-635. Citation URL: http://dx.doi.org/10.1016/j.molcel.2007.06.038

Questions or comments to oreganno@bcgsc.ca. (Archived here)