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Dataset Description

Dataset: Yeast Regulatory Map (OREGDS00010) Description: Genome-wide location analysis (ChIP-chip) was used to determine the genomic occupancy of 203 Yeast DNA-binding transcriptional regulators in rich media conditions and for 84 of these regulators, in at least 1 of 12 other environmental conditions. These proteins are likely to represent nearly all the DNA-binding transcriptional regulators in the yeast genome. The genome-wide location analysis identified specific interactions between the regulators and the promoter regions they bind. These regions were further refined using a conservation and motif scanning techniques to identify a set of high confidence binding sites and create a preliminary transcriptional regulatory map for Saccharomyces. Dataset URL: http://fraenkel.mit.edu/Harbison/ Citation Information: Harbison CT, Gordon DB, Lee TI, Rinaldi NJ, Macisaac KD, Danford TW, Hannett NM, Tagne JB, Reynolds DB, Yoo J, Jennings EG, Zeitlinger J, Pokholok DK, Kellis M, Rolfe PA, Takusagawa KT, Lander ES, Gifford DK, Fraenkel E, Young RA. 2004. Transcriptional regulatory code of a eukaryotic genome. Nature. 431(7004):99-104. Citation URL: http://dx.doi.org/10.1038/nature02800

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