22-Sep-2005 Reduced warfarin requirement population 22-Sep-2005 OREGEC00000 OREGES00010 OREGET00006 smontgom 79001 VKORC1 NCBI 1 POSITIVE OUTCOME 15930419 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000002 REGULATORY HAPLOTYPE 22-Sep-2005 0 reference_sequence gcacagtggctcacgcctgtaatcccagcactttaggaagccaaggagggTggatcatgaggtcaggagtttgagaccagcctggccaatatggtgaaacc 0 false GERMLINE 0 variant_sequence gcacagtggctcacgcctgtaatcccagcactttaggaagccaaggagggCggatcatgaggtcaggagtttgagaccagcctggccaatatggtgaaacc 0 false 22-Sep-2005 0 reference_sequence atccctctgggaagtcaagcaagagaagacctgaaaaacaaccattggccGggtgcggtggctcacgcctataatcctagcattttgggaggccgaggtgg 0 false GERMLINE 0 variant_sequence atccctctgggaagtcaagcaagagaagacctgaaaaacaaccattggccAggtgcggtggctcacgcctataatcctagcattttgggaggccgaggtgg 0 false 22-Sep-2005 0 reference_sequence catggaatcctgacgtggccaaaggtgcccggtgccaggagatcatcgacCcttggactaggatgggaggtcggggaacagaggatagcccaggtggcttc 0 false GERMLINE 0 variant_sequence catggaatcctgacgtggccaaaggtgcccggtgccaggagatcatcgacTcttggactaggatgggaggtcggggaacagaggatagcccaggtggcttc 0 false 22-Sep-2005 0 reference_sequence atgcaatcttggtgatccacacagctgacagccagctagctgctcatcacGgagcgtcctgcgggtggggatgtggggaggtaactaacaggagtctttta 0 false GERMLINE 0 variant_sequence atgcaatcttggtgatccacacagctgacagccagctagctgctcatcacCgagcgtcctgcgggtggggatgtggggaggtaactaacaggagtctttta 0 false 22-Sep-2005 0 reference_sequence tcacccttcccagctccagagaaggcatcactgagggaggcccagcaccaCggtcctggctgacacatggttcagacttggccgatttatttaagaaattt 0 false GERMLINE 0 variant_sequence tcacccttcccagctccagagaaggcatcactgagggaggcccagcaccaTggtcctggctgacacatggttcagacttggccgatttatttaagaaattt 0 false 23-Sep-2005 High warfarin requirement group 23-Sep-2005 OREGEC00000 OREGES00010 OREGET00006 smontgom 79001 VKORC1 NCBI 2 POSITIVE OUTCOME 15930419 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000001 REGULATORY HAPLOTYPE 23-Sep-2005 0 reference_sequence gcacagtggctcacgcctgtaatcccagcactttaggaagccaaggagggTggatcatgaggtcaggagtttgagaccagcctggccaatatggtgaaacc 0 false GERMLINE 0 variant_sequence gcacagtggctcacgcctgtaatcccagcactttaggaagccaaggagggTggatcatgaggtcaggagtttgagaccagcctggccaatatggtgaaacc 0 false 23-Sep-2005 0 reference_sequence atccctctgggaagtcaagcaagagaagacctgaaaaacaaccattggccGggtgcggtggctcacgcctataatcctagcattttgggaggccgaggtgg 0 false GERMLINE 0 variant_sequence atccctctgggaagtcaagcaagagaagacctgaaaaacaaccattggccGggtgcggtggctcacgcctataatcctagcattttgggaggccgaggtgg 0 false 23-Sep-2005 0 reference_sequence catggaatcctgacgtggccaaaggtgcccggtgccaggagatcatcgacCcttggactaggatgggaggtcggggaacagaggatagcccaggtggcttc 0 false GERMLINE 0 variant_sequence catggaatcctgacgtggccaaaggtgcccggtgccaggagatcatcgacCcttggactaggatgggaggtcggggaacagaggatagcccaggtggcttc 0 false 23-Sep-2005 0 reference_sequence atgcaatcttggtgatccacacagctgacagccagctagctgctcatcacGgagcgtcctgcgggtggggatgtggggaggtaactaacaggagtctttta 0 false GERMLINE 0 variant_sequence atgcaatcttggtgatccacacagctgacagccagctagctgctcatcacGgagcgtcctgcgggtggggatgtggggaggtaactaacaggagtctttta 0 false 23-Sep-2005 0 reference_sequence tcacccttcccagctccagagaaggcatcactgagggaggcccagcaccaCggtcctggctgacacatggttcagacttggccgatttatttaagaaattt 0 false GERMLINE 0 variant_sequence tcacccttcccagctccagagaaggcatcactgagggaggcccagcaccaCggtcctggctgacacatggttcagacttggccgatttatttaagaaattt 0 false The CT60 polymorphism is 3' of the CTLA4 gene and is associated to Grave's Disease. The allele was confirmed using ASTQ (allele-specific transcript quantification) to reduce expression. 19-Sep-2005 smontgom 19-Sep-2005 19-Sep-2005 OREGEC00001 OREGES00009 OREGET00004 smontgom 1493 CTLA4 NCBI 3 POSITIVE OUTCOME 12724780 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000000 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 19-Sep-2005 0 reference_sequence ttttgatttcttcaccactatttgggatataacAtgggttaacacagacata 0 false rs3087243 dbSNP GERMLINE 0 variant_sequence ttttgatttcttcaccactatttgggatataacGtgggttaacacagacata 0 false 23-Sep-2005 Upregulated 2.9 fold (No change to steady-state expression using RT-PCR) 23-Sep-2005 OREGEC00003 OREGES00012 OREGET00005 smontgom 9628 RGS6 NCBI 4 POSITIVE OUTCOME 15375002 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000003 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 23-Sep-2005 0 reference_sequence ccaggccctggacctgcggtaggaaCggtcaggaggactgcatcaggcccg 0 false rs2074647 dbSNP GERMLINE 0 variant_sequence ccaggccctggacctgcggtaggaaTggtcaggaggactgcatcaggcccg 0 false 23-Sep-2005 Unknown factor bound; Likely not AP2; Expression; T allele drives expression 2.8-fold; C allele drives expression 2.2-fold. 23-Sep-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 3938 LCT NCBI 5 POSITIVE OUTCOME 12915462 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000004 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 23-Sep-2005 0 reference_sequence gataagataatgtagCccctggcctcaaag 0 false rs4988235 dbSNP GERMLINE 0 variant_sequence gataagataatgtagTccctggcctcaaag 0 false 23-Sep-2005 Confirmed that differential binding occured for this polymorphism. Binding occured for T allele. 23-Sep-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Confirmed binding of C/EBP Beta to binding site. 23-Sep-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom 3576 IL8 NCBI 6 POSITIVE OUTCOME 15085176 0 sequence_with_flank EMPTY 0 false 0 sequence GTTGTTCAAT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000005 1051 CEBPB NCBI REGULATORY POLYMORPHISM 23-Sep-2005 0 reference_sequence aaagaactctaactctttatataggaagtTgttcaatgttgtcagtt 0 false rs2227306 dbSNP GERMLINE 0 variant_sequence aaagaactctaactctttatataggaagtCgttcaatgttgtcagtt 0 false Test population Ethiopian 27-Sep-2005 smontgom 27-Sep-2005 Likely ETS-family binding site 27-Sep-2005 OREGEC00001 OREGES00003 OREGET00001 smontgom In the presence of TCDD enzyme this allele had altered expression activity. However, without the TCDD, the results were inconclusive (for altered expression). 27-Sep-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 1544 CYP1A2 NCBI 11 POSITIVE OUTCOME 12920202 0 search_space ACCCTGAACCCTAAAGACAGCTGTACCTTCATCCCCAGGGACCCAGCACCCCTTCTGGCCTATCCCCAAAGAGTCACCCTGGGTCTTAGGTAGTAGGTGGAGCTGAGGGATAATGGCCCAAGGCCAAGAGTTGATCCTTCCAACTTTGTTCAGTGATCCAGCTTTCATATCAGGTGATCAGGACAACCAGGCCAATCTGATAGGGGGCGGTGTTTATAAAAAGGCCACTCACCTAGAGCCAGAAGCTCCACACCAGCCATTACAACCCTGCCAATCTCAAGCACCTGCCTCTACAGGTACCTTTCTTGGGACCAATTTACAATCTCTGGGATCCCCAACTATAGAACCTGGAAGCTAGTGGGGACAGAAAGACGGGGAGCCTGGGCTAGGTGTAGGGGTCCTGAGTTCCGGGCTTTGCTACCCAGCTCTTGACTTCTGTTTCCCGATTTTAAATGAGCAGTTTGGACTAAGCCATTTTTAAGGAGAGCGATGGGGAGGGCTTCCCCCTTAGCACAAGGGCAGCCCTGGCCCTGGCTGAAGCCCAACCCCAACCTCCAAGACTGTGAGAGGATGGGGACTCATCCCTGGAGGAGGTGCCCCTCCTGGTATTGATAAAGAATGCCCTGGGGAGGGGGCATCACAGGCTATTTGAACCAGCCCTGGGACCTTGGCCACCTCAGTGTCACTGGGTAGGGGGAACTCCTGGTCCCTTGGGTATATGGAAGGTATCAGCAGAAAGCCAGCACTGGCAGGGACTCTTTGGTACAATACCCAGCATGCATGCTGTGCCAGGGGCTGACAAGGGTGCTGTCCTTGGCTTCCCCATTTTGGAGTGGTCACTTGCCTCTACTCCAGCCCCAGAAGTGGAAACTGAGATGATGTGTGGAGGAGAGAGCCAGCGTTCATGTTGGGAATCTTGAGGCTCCTTTCCAGCTCTCAGATTCTGTGATGCTCAAAGGGTGAGCTCTGTGGGCCCAGGACGCATGGTAGATGGAGCTTAGTCTTTCTGGTATCCAGCTGGGAGCCAAGCACAGAACACGCATCAGTGTTTATCAAATGACTGAGGAAATGAATGAATGAATGTCTCCATCTCAACCCTCAGCCTGGTCCCTCCTTTTTTCCCTGCAGTTGGTACAG 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000008 UNKNOWN-ETS UNKNOWN-ETS USER DEFINED REGULATORY POLYMORPHISM 27-Sep-2005 0 reference_sequence tgagttcCgggctttgctacccag 0 false rs12720461 dbSNP GERMLINE 0 variant_sequence tgagttcTgggctttgctacccag 0 false The TATA binding protein (TBP) was demonstrated to be disrupted in the presence of the G allele resulting in 50% decreased expression from wild-type. 28-Sep-2005 smontgom 28-Sep-2005 Cell type: human hepatoma cell line, B16A2 28-Sep-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 1548 CYP2A6 NCBI 12 POSITIVE OUTCOME 11394901 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000009 TBP TBP USER DEFINED REGULATORY POLYMORPHISM 28-Sep-2005 0 reference_sequence catccctctttttcaggcagtaTaaaggcaaaggagggg 0 false GERMLINE 0 variant_sequence catccctctttttcaggcagtaGaaaggcaaaggagggg 0 false 28-Sep-2005 When allele (G) present, CYP2A6 is expressed at 48% of wild-type activity. 28-Sep-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom ROughly two to four-fold lower affinity for nuclear extracts in the presence of the variant (G) allele. 28-Sep-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom 1548 CYP2A6 NCBI 14 POSITIVE OUTCOME 14974084 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000012 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 28-Sep-2005 0 reference_sequence tgcccactgtctgttttctgtcctctgtAgatctttatataaaatgag 0 false rs4803381 dbSNP GERMLINE 0 variant_sequence tgcccactgtctgttttctgtcctctgtGgatctttatataaaatgag 0 false 28-Sep-2005 The TATATAA sequence is important for the binding of a larger DNA-complex, but a smaller complex is able to bind the upstream part of this region (TTCTGTCCTCTGTAGATCTT) 28-Sep-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom 1548 CYP2A6 NCBI 15 POSITIVE OUTCOME 14974084 0 search_space TTCTGTCCTCTGTAGATCTTTATATAA 0 false 0 sequence TTCTGTCCTCTGTAGATCTTTATATAA 0 false 0 sequence_with_flank CTCACACATGTCCCCTGCCCACTGTCTGTTTTCTGTCCTCTGTAGATCTTTATATAAAATGAGAAACATAAACAACAATCATAATATTA 0 false Homo sapiens OREG0000013 REGULATORY REGION 28-Sep-2005 NF-Y pulled down search sequence. 28-Sep-2005 OREGEC00002 OREGES00005 OREGET00003 smontgom Competition eliminated with variant allele (G). 28-Sep-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Cell line: Human hepatoma HepG2. 22% reduction in activity with variant (G) allele. 28-Sep-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 1548 CYP2A6 NCBI 19 POSITIVE OUTCOME 15247629 0 search_space GAGGATCTGGGTTGGAAACCAGCGGACAACCCTTGGGACACTTGAGATTTTTCCACCATTTGGGGGTTGTTATTACTATTTCTCCAGACCTAGCCAATCCCTCTGCCAACCGCTAACTCCAGGTACTCTTCTCCAGGTGTGGGGAAAGTTCCCCTGAAATATGGCTCTGGTCTTCCTCCCCTTCCCAATCAGAGATGGGCAGTGGAGGTTCTATGGCACCCATCCTGGCCTCACTCTGAGGTTCCAATGAGGATTCTGGGCATCAAGAGACAGCTCTGGGCAAAAGCAAAATCAAGTCAGCCCCTGGACCCAGTGCTGGGCTGCTGG 0 false 0 sequence CCAAT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000019 4800 NFYA NCBI REGULATORY POLYMORPHISM 28-Sep-2005 0 reference_sequence ctccccttcccaAtcagagatggg 0 false GERMLINE 0 variant_sequence ctccccttcccaGtcagagatggg 0 false Neutral outcome entered. Primary authors indicate that depth of population sampling cannot only supports a minor role of this haplotype in determing the ultrarapid metabolizer group. 28-Sep-2005 smontgom 28-Sep-2005 Variant associated to ultrarapid metabolizer group. 28-Sep-2005 OREGEC00000 OREGES00010 OREGET00006 smontgom 1565 CYP2D6 NCBI 20 NEUTRAL OUTCOME 11207030 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000020 REGULATORY HAPLOTYPE 28-Sep-2005 0 reference_sequence caacttggaagaaccCggtctctacaaaaa 0 false GERMLINE 0 variant_sequence caacttggaagaaccGggtctctacaaaaa 0 false 29-Sep-2005 Cell line: HepG2 Human hepatocarcinoma 29-Sep-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 1576 CYP3A4 NCBI 22 POSITIVE OUTCOME 14742674 0 search_space GGTACCTGGTTCATCTCATTGGGACTGGTTGGACAAGAGGGTGCAGCCCACGGAGGGTGAGCCAAAGCAGGGTGGGGCGTCGCCTCACCTGGGAAGCACAAGGGGTCGTGGAATTTTCTCCCCTACCCAAGGAAAGCCATAAGGGACTGAGCCTGAGGAACTGTGCACTCTGGCCCAGATACTGCACTTTTCCCATGGTCTTTGCAACCCGCAGACCAGGAGATTCCCTCCGGTGCCTATGCCACCAGGGCCCTGGGTTTCAAGCACAAAACTGGGCAGCCATTTGGGCAGACACCGAACTAGCTGCAGGAGTTTTTTTTTTTTTTTTTCCATACCCCATTGGCACCTGGAACGCCAGTGAGACAGAACCGTTCACTCCCCTGGAAAGGGGGCTGAAACCAGGGATCCAAGTGGTCTGGCTCGGTGGGCCCCACCCCCATGGAGCCCAGCAAACAAAGATTCACTTGGCTTGAAATTCTTGCTGCCAGCACAGCAGCAGTCTGAGATTGACCTGGGACCCTCGAACTTGGTTGGGTGCTGTGGGGGGGCATCTTCCATTGCTGAGGCTTGAGTAGGTGGTTTTACCTTCGCGGTGTAAACAAAGCTGCTGGGAAGTTTGAACTGGGTGGAGCTCACCACAGCTCAGTAAGGCCACTGTGGCCAGACTGCCTCTCTGGATTTCTCCTCTCTGGGAAGGATATCTCTGAAAAAAAGGCAGCAGCCCCAGTCAGGGACTTATAGATGAAACCCCCATCTCCCTGGGACAGAGCCCCTCGGGGAAGAGGTGGCTTCCACCATTGTGGAAGACTGTGTGGCAATTCCTCACGGATTTAGAACTAGAGATACCATTTGACCCAGCAATCCCATTACTGGGTGTATACCCATAGGATTATAAATCATTCTACTATAAAGACACATGCACACTTATGTTTATTGTAACACTATTTACAATAGCAATGACCTGGAACCAATCCAAAAGCCCATCAATGATAGACTGAATAAAGAAAATGTGGCACATATACACTGTGGAATACTATGCAGCCATAAAAAAGGATGAGTTCATGTCCTTTGCAGAGACATGGATGAAGCTGGAAACCATCATTCTCAGCAAACTAGCACAATAACAGAAAACCAAACACTGCATGTTGTCACTCATAAGTGGGAGTTAAACAATGAGAACACATGGACACAGGGAGGGGAACGTCACACACTGGGGCATGTCGGGGAGTGGGGGCCTACGGGAGGGATAGCATTAGCAGAAATACCTAATGTAGGTGACGGGTTGATGGGTGCAGCAAACCACCATGGCACATATACACCTATGTAATAAAACTGCACGTTCTGCACATGTACCCCAGAACTTAAAGTATAATTAATAATAATAATAATTTCTGGGCATGTAAGTAGCTGTCTTTCAGGTTCTACTTTGATACATATTCTGAGAGAATTAAACCTGTCAAAGAAACCTTGACTTTCAATGGCAGGCACTGGAATTGACCCTAATAATGTGTTTTGGGGTAAGCCTACTCATATTCTCAACCTGTCTGCAGTAGTCGTTAGAATCTGAACTTCCTGAAGTTCATGTGCAAAGTTGAGTTAATTGTTTAATATTCAACAAGGATTATGCCAGTAAGATGGTAGGAAAATATTAGATATGTGTCATCACTGCTGGTATTATTTAAACTGCAACATATTTTAGCTGGCTGCTGATCTCAGCCACCATGCCTGCATTTTATCTCTGTCTCGTGGTCTGCAACCTTGGAAGCTTTGAACTTAGCTCATAGAATCCTGGGCATCAAGAACATGTGGTTCTAATGGCTAGATAGGGAATGAGAGTAAAAGGATTTTGCCCACGGTCACGTGAGTAAACAACAGATTTGGAGGGGTCTGGACTACTGTGATGACTTCATTCTGACAATATGTTCCAGTTGTCCTTTCATTTCCTCCTAATCACATGTCTGGTCTGATCTGGCTGTTTCCCACCTTCCAATTCCTGCCTTCTCCAATGCTCCCTTCCGTAGGTCACTCTGTGGCTCAGAGACCCTGCTTAGCAAGCGCCCAACCTTTCAATTATTTGTTCAGTAAAACTTGAACTCATGTCTCCCCTTCTTGATAAAAAGAAAATACGTTATGTAATGTCGGGTTACTCTATAACTCTTGTCCTGTCTCTCGGCAACTACTGAACTAACTGTTTTCATATTGAGCAAACGTTTATGGAAGGACTGCCAAGAGTCAGGTACTAGGCTTGGTAATATTCCCCGTTCTCTCTAGTCAAAGCCAACACCAGCCAGACTTGCAGATCTAGGTCCCAAGCCCACTGCAGATCACAGGCCAGGGTCTGGTCTCCTCTGAGCTCCTTTGGGAGGGAAAGACAGAATTATTAACACCCATTTTGTAGATTAGGCAACTGAGGCTGAGGAAGTTTAAATAACTCAGACAGGGCCTGCACGTCAGTCATATTCCAA 0 false 0 sequence CCTGTCTGCAGTAGTCGTTAGAATCTGAACTTCCTGAAGTTCATGTGCAAAGTTGAGTTAATTGTTTAATATTCAACAAGGATTATGCCAGTAAGATGGTAGGAAAATATTAGATATGTGTCATCACTGCTGGTATTATTTAAACTGCAACATATTTTAGCTGGCTGCTGATCTCAGCCACCATGCCTGCATTTTATCTCTGTCTCGTGGTCTGCAACCTTGGAAGCTTTGAACTTAGCTCATAGAATCCTGGGCATCAAGAACATGTGGTTCTAATGGCTAGATAGGGAATGAGAGTAAAAGGATTTTGCCCACGGTCACGTGAGTAAACAACAGATTTGGAGGGGTCTGGACTACTGTGATGACTTCATTCTGACAATATGTTCCAGTTGTCCTTTCATTTCCTCCTAATCACATGTCTGGTCTGATCTGGCTGTTTCCCACCTTCCAATTCCTGCCTTCTCCAATGCTCCCTTCCGTAGGTCACTCTGTGGCTCAGAGACCCTGCTTAGCAAGCGCCCAACCTTTCAATTATTTGTTCAGTAAAACTTGAACTCATGTCTCCCCTTCTTGATAAAAAGAAAATACGTTATGTAATGTCGGGTTACTCTATAACTCTTGTCCTGTCTCTCGGCAACTACTGAACTAACTGTTTTCATATTGAGCAAACGTTTATGGAAGGACTGCCAAGAGTCAGGTACTAGGCTTGGTAATATTCCCCGTTCTCTCTAGTCAAAGCCAACACCAGCCAGACTTGCAGATCTAGGTCCCAAGCCCACTGCAGATCACAGGCCAGGGTCTGGTCTCCTCTGAGCTCCTTTGGGAGGGAAAGACAGAATTATTAACACCCATTTTGTAGATTAGGCAACTGAGGCTGAGGAAGTTTAAATAACTCAGACAGGGCCTGCACGTCAGTCATATTCCAA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000022 REGULATORY REGION Enhancer activity reduced by 64% in presence of allele (TGT). Allele is rare in French population. Cell line is human liver. 29-Sep-2005 smontgom 29-Sep-2005 Cell line: Human liver HepG2 29-Sep-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 29-Sep-2005 OREGEC00002 OREGES00003 OREGET00001 smontgom 1576 CYP3A4 NCBI 23 POSITIVE OUTCOME 14742674 0 search_space GTCGTTAGAATCTGAACTTCCTGAAGTTCATGTGCAAAGTTGAGTTAATTGTTTAATATTCAACAAGGATTATGCCAGTAAGATGGTAGGAAAATATTAGATATGTGTCATCACTGCTGGTATTATTTAAACTGCAACATATTTTAGCTGGCTGCTGATCTCAGCCACCATGCCTGCATTTTATCTCTGTCTCGTGGTCTGCAACCTTGGAAGCTTTGAACTTAGCTCATAGAATCCTGGGCATCAAGAACATGTGGTTCTAATGGCTAGATAGGGAATGAGAGTAAAAGGATTTTGCCCACGGTCACGTGAGTAAACAACAGATTTGGAGGGGTCTGGACTACTGTGATGACTTCATTCTGACAATATGTTCCAGTTGTCCTTTCATTTCCTCCTAATCACATGTCTGGTCTGATCTGGCTGTTTCCCACCTTCCAATTCCTGCCTTCTCCAATGCTCCCT 0 false 0 sequence CATGTG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000023 7391 USF1 NCBI REGULATORY POLYMORPHISM 29-Sep-2005 0 reference_sequence gcatcaagaacatgtggttctaatgg 0 false GERMLINE 0 variant_sequence gcatcaagaacatgtTGTggttctaatgg 0 false Binding sequence was determined computationally as the canonical binding sequence. Only the 3' most AA sequence of the binding site was biologically tested. 30-Sep-2005 smontgom 30-Sep-2005 Antibodies to HNF-4alpha not HNF-4gamma supershifted bound complex. 30-Sep-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom aagttcatgtgcaCCgttgagttaatt (AA to CC mutation in HNF-4 binding site as competitor) does not compete for binding with HNF-4 sequence. HNF-4 sequence in excess competes out complex formation. 30-Sep-2005 OREGEC00001 OREGES00003 OREGET00001 smontgom aagttcatgtgcaCCgttgagttaatt (AA to CC mutation in HNF-4 binding site) reduces enhancer activity by 19% 30-Sep-2005 OREGEC00002 OREGES00004 OREGET00002 smontgom 1576 CYP3A4 NCBI 54 POSITIVE OUTCOME 14742674 0 search_space GTCGTTAGAATCTGAACTTCCTGAAGTTCATGTGCAAAGTTGAGTTAATTGTTTAATATTCAACAAGGATTATGCCAGTAAGATGGTAGGAAAATATTAGATATGTGTCATCACTGCTGGTATTATTTAAACTGCAACATATTTTAGCTGGCTGCTGATCTCAGCCACCATGCCTGCATTTTATCTCTGTCTCGTGGTCTGCAACCTTGGAAGCTTTGAACTTAGCTCATAGAATCCTGGGCATCAAGAACATGTGGTTCTAATGGCTAGATAGGGAATGAGAGTAAAAGGATTTTGCCCACGGTCACGTGAGTAAACAACAGATTTGGAGGGGTCTGGACTACTGTGATGACTTCATTCTGACAATATGTTCCAGTTGTCCTTTCATTTCCTCCTAATCACATGTCTGGTCTGATCTGGCTGTTTCCCACCTTCCAATTCCTGCCTTCTCCAATGCTCCCT 0 false 0 sequence TCATGTGCAAAGTTGAGTT 0 false 0 sequence_with_flank GTAGTCGTTAGAATCTGAACTTCCTGAAGTTCATGTGCAAAGTTGAGTTAATTGTTTAATATTCAACA 0 false Homo sapiens OREG0000053 3172 HNF4A NCBI TRANSCRIPTION FACTOR BINDING SITE Binding sequence was determined computationally as the canonical binding sequence. Only the CTT sequence of the binding site was biologically tested. 30-Sep-2005 smontgom 30-Sep-2005 Antibodies to HNF-4alpha supershifted bound complex. 30-Sep-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom ggaagctttgaaAGCagctcatagaa (CTT to AGC mutation in HNF-4 binding site as competitor) does not compete for binding with HNF-4 sequence. HNF-4 sequence in excess competes out complex formation. 30-Sep-2005 OREGEC00001 OREGES00003 OREGET00001 smontgom ggaagctttgaaAGCagctcatagaa (CTT to AGC mutation in HNF-4 binding site) reduces enhancer activity by 44% 30-Sep-2005 OREGEC00002 OREGES00004 OREGET00002 smontgom 1576 CYP3A4 NCBI 55 POSITIVE OUTCOME 14742674 0 search_space GTCGTTAGAATCTGAACTTCCTGAAGTTCATGTGCAAAGTTGAGTTAATTGTTTAATATTCAACAAGGATTATGCCAGTAAGATGGTAGGAAAATATTAGATATGTGTCATCACTGCTGGTATTATTTAAACTGCAACATATTTTAGCTGGCTGCTGATCTCAGCCACCATGCCTGCATTTTATCTCTGTCTCGTGGTCTGCAACCTTGGAAGCTTTGAACTTAGCTCATAGAATCCTGGGCATCAAGAACATGTGGTTCTAATGGCTAGATAGGGAATGAGAGTAAAAGGATTTTGCCCACGGTCACGTGAGTAAACAACAGATTTGGAGGGGTCTGGACTACTGTGATGACTTCATTCTGACAATATGTTCCAGTTGTCCTTTCATTTCCTCCTAATCACATGTCTGGTCTGATCTGGCTGTTTCCCACCTTCCAATTCCTGCCTTCTCCAATGCTCCCT 0 false 0 sequence CTTTGAACTTAGCTCATAG 0 false 0 sequence_with_flank GTCTCGTGGTCTGCAACCTTGGAAGCTTTGAACTTAGCTCATAGAATCCTGGGCATCAAG 0 false Homo sapiens OREG0000054 3172 HNF4A NCBI TRANSCRIPTION FACTOR BINDING SITE Binding sequence was determined computationally as the canonical binding sequence. Only the AAC sequence of the binding site was biologically tested. 30-Sep-2005 smontgom 30-Sep-2005 Antibodies to HNF-1 supershifted bound complex. 30-Sep-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom ttaattgtttaatattcCTGaagga (AAC to CTG mutation in HNF-1 binding site as competitor) does not compete for binding with HNF-1 sequence. HNF-1 sequence in excess competes out complex formation. 30-Sep-2005 OREGEC00001 OREGES00003 OREGET00001 smontgom ttaattgtttaatattcCTGaagga (AAC to CTG mutation in HNF-1 binding site) reduces enhancer activity by 30% 30-Sep-2005 OREGEC00002 OREGES00004 OREGET00002 smontgom 1576 CYP3A4 NCBI 56 POSITIVE OUTCOME 14742674 0 search_space GTCGTTAGAATCTGAACTTCCTGAAGTTCATGTGCAAAGTTGAGTTAATTGTTTAATATTCAACAAGGATTATGCCAGTAAGATGGTAGGAAAATATTAGATATGTGTCATCACTGCTGGTATTATTTAAACTGCAACATATTTTAGCTGGCTGCTGATCTCAGCCACCATGCCTGCATTTTATCTCTGTCTCGTGGTCTGCAACCTTGGAAGCTTTGAACTTAGCTCATAGAATCCTGGGCATCAAGAACATGTGGTTCTAATGGCTAGATAGGGAATGAGAGTAAAAGGATTTTGCCCACGGTCACGTGAGTAAACAACAGATTTGGAGGGGTCTGGACTACTGTGATGACTTCATTCTGACAATATGTTCCAGTTGTCCTTTCATTTCCTCCTAATCACATGTCTGGTCTGATCTGGCTGTTTCCCACCTTCCAATTCCTGCCTTCTCCAATGCTCCCT 0 false 0 sequence TTGTTTAATATTCAACA 0 false 0 sequence_with_flank ATGTGCAAAGTTGAGTTAATTGTTTAATATTCAACAAGGATTATGCCAGTAAGA 0 false Homo sapiens OREG0000055 6927 TCF1 NCBI TRANSCRIPTION FACTOR BINDING SITE Binding sequence was determined computationally as the canonical binding sequence. Only the GTG sequence of the binding site was biologically tested. 30-Sep-2005 smontgom 30-Sep-2005 Antibodies to USF1 supershifted bound complex. 30-Sep-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom gcatcaagaacatTAGgttctaatgg (GTG to TAG mutation in E-box binding site as competitor) does not compete for binding with E-box sequence. E-box sequence in excess competes out complex formation. 30-Sep-2005 OREGEC00001 OREGES00003 OREGET00001 smontgom gcatcaagaacatTAGgttctaatgg (GTG to TAG mutation in E-box binding site) reduces enhancer activity 33% 30-Sep-2005 OREGEC00002 OREGES00004 OREGET00002 smontgom 1576 CYP3A4 NCBI 57 POSITIVE OUTCOME 14742674 0 search_space GTCGTTAGAATCTGAACTTCCTGAAGTTCATGTGCAAAGTTGAGTTAATTGTTTAATATTCAACAAGGATTATGCCAGTAAGATGGTAGGAAAATATTAGATATGTGTCATCACTGCTGGTATTATTTAAACTGCAACATATTTTAGCTGGCTGCTGATCTCAGCCACCATGCCTGCATTTTATCTCTGTCTCGTGGTCTGCAACCTTGGAAGCTTTGAACTTAGCTCATAGAATCCTGGGCATCAAGAACATGTGGTTCTAATGGCTAGATAGGGAATGAGAGTAAAAGGATTTTGCCCACGGTCACGTGAGTAAACAACAGATTTGGAGGGGTCTGGACTACTGTGATGACTTCATTCTGACAATATGTTCCAGTTGTCCTTTCATTTCCTCCTAATCACATGTCTGGTCTGATCTGGCTGTTTCCCACCTTCCAATTCCTGCCTTCTCCAATGCTCCCT 0 false 0 sequence CATGTG 0 false 0 sequence_with_flank GCTCATAGAATCCTGGGCATCAAGAACATGTGGTTCTAATGGCTAGATAGGGAATGAGA 0 false Homo sapiens OREG0000056 7391 USF1 NCBI TRANSCRIPTION FACTOR BINDING SITE Binding sequence was determined computationally as the canonical binding sequence. Only the CGT sequence of the binding site was biologically tested. 30-Sep-2005 smontgom 30-Sep-2005 Antibodies to USF1 supershifted bound complex. 30-Sep-2005 OREGEC00002 OREGES00001 OREGET00001 smontgom tgcccacggtcaTAAgagtaaacaac (CGT to TAA mutation in E-box binding site as competitor) does not compete for binding with E-box sequence. E-box sequence in excess competes out complex formation. 30-Sep-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom tgcccacggtcaTAAgagtaaacaac (CGT to TAA mutation in E-box binding site) reduces enhancer activity by 43% 30-Sep-2005 OREGEC00002 OREGES00004 OREGET00002 smontgom 1576 CYP3A4 NCBI 58 POSITIVE OUTCOME 14742674 0 search_space GTCGTTAGAATCTGAACTTCCTGAAGTTCATGTGCAAAGTTGAGTTAATTGTTTAATATTCAACAAGGATTATGCCAGTAAGATGGTAGGAAAATATTAGATATGTGTCATCACTGCTGGTATTATTTAAACTGCAACATATTTTAGCTGGCTGCTGATCTCAGCCACCATGCCTGCATTTTATCTCTGTCTCGTGGTCTGCAACCTTGGAAGCTTTGAACTTAGCTCATAGAATCCTGGGCATCAAGAACATGTGGTTCTAATGGCTAGATAGGGAATGAGAGTAAAAGGATTTTGCCCACGGTCACGTGAGTAAACAACAGATTTGGAGGGGTCTGGACTACTGTGATGACTTCATTCTGACAATATGTTCCAGTTGTCCTTTCATTTCCTCCTAATCACATGTCTGGTCTGATCTGGCTGTTTCCCACCTTCCAATTCCTGCCTTCTCCAATGCTCCCT 0 false 0 sequence CACGTG 0 false 0 sequence_with_flank GAGAGTAAAAGGATTTTGCCCACGGTCACGTGAGTAAACAACAGATTTGGAGGGGT 0 false Homo sapiens OREG0000057 7391 USF1 NCBI TRANSCRIPTION FACTOR BINDING SITE Binding sequence was determined computationally as the canonical binding sequence. Mutation analysis of GT in binding site did not compete out binding in gel shift competition. This is likely because the change from the canonical TG sequence wasn't significant enough (when compared to other binding sites from this reference). However, this conclusion, is in disagreement with the effect observed in the reported gene assay in vitro (where the mutation caused a reduction in activity of 47%) 30-Sep-2005 smontgom 30-Sep-2005 Antibodies to USF1 supershifted bound complex. 30-Sep-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom tcctcctaatcacaGTtctggtctga (mutation in E-box binding site of TG to GT) did not compete out binding. However, binding was compete out in the presence of excess unlabelled E-box sequence. 30-Sep-2005 OREGEC00001 OREGES00003 OREGET00001 smontgom tcctcctaatcacaGTtctggtctga (mutation in E-box binding site of TG to GT) reduces enhancer activity by 47% 30-Sep-2005 OREGEC00002 OREGES00004 OREGET00002 smontgom 1576 CYP3A4 NCBI 59 POSITIVE OUTCOME 14742674 0 search_space GTCGTTAGAATCTGAACTTCCTGAAGTTCATGTGCAAAGTTGAGTTAATTGTTTAATATTCAACAAGGATTATGCCAGTAAGATGGTAGGAAAATATTAGATATGTGTCATCACTGCTGGTATTATTTAAACTGCAACATATTTTAGCTGGCTGCTGATCTCAGCCACCATGCCTGCATTTTATCTCTGTCTCGTGGTCTGCAACCTTGGAAGCTTTGAACTTAGCTCATAGAATCCTGGGCATCAAGAACATGTGGTTCTAATGGCTAGATAGGGAATGAGAGTAAAAGGATTTTGCCCACGGTCACGTGAGTAAACAACAGATTTGGAGGGGTCTGGACTACTGTGATGACTTCATTCTGACAATATGTTCCAGTTGTCCTTTCATTTCCTCCTAATCACATGTCTGGTCTGATCTGGCTGTTTCCCACCTTCCAATTCCTGCCTTCTCCAATGCTCCCT 0 false 0 sequence CACATG 0 false 0 sequence_with_flank TTTCCTCCTAATCACATGTCTGGTCTGATCTGGCTGTTTCC 0 false Homo sapiens OREG0000058 7391 USF1 NCBI TRANSCRIPTION FACTOR BINDING SITE Binding sequence was determined computationally as the canonical binding sequence. Only the AC sequence of the binding site was biologically tested. 30-Sep-2005 smontgom 30-Sep-2005 Addition of unlabelled CRE sequence in excess eliminated protein binding. When competed with mutant CRE sequence, the binding was not abolished tgGAttca (change from AC to GA) 30-Sep-2005 OREGEC00001 OREGES00003 OREGET00001 smontgom Antibodies to Jun family super shifted complex. 30-Sep-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom tgGAttca (change from AC to GA) mutation reduced enhancer activity by 80% 30-Sep-2005 OREGEC00002 OREGES00004 OREGET00002 smontgom 1576 CYP3A4 NCBI 60 POSITIVE OUTCOME 14742674 0 search_space GTCGTTAGAATCTGAACTTCCTGAAGTTCATGTGCAAAGTTGAGTTAATTGTTTAATATTCAACAAGGATTATGCCAGTAAGATGGTAGGAAAATATTAGATATGTGTCATCACTGCTGGTATTATTTAAACTGCAACATATTTTAGCTGGCTGCTGATCTCAGCCACCATGCCTGCATTTTATCTCTGTCTCGTGGTCTGCAACCTTGGAAGCTTTGAACTTAGCTCATAGAATCCTGGGCATCAAGAACATGTGGTTCTAATGGCTAGATAGGGAATGAGAGTAAAAGGATTTTGCCCACGGTCACGTGAGTAAACAACAGATTTGGAGGGGTCTGGACTACTGTGATGACTTCATTCTGACAATATGTTCCAGTTGTCCTTTCATTTCCTCCTAATCACATGTCTGGTCTGATCTGGCTGTTTCCCACCTTCCAATTCCTGCCTTCTCCAATGCTCCCT 0 false 0 sequence TGACTTCA 0 false 0 sequence_with_flank TTTGGAGGGGTCTGGACTACTGTGATGACTTCATTCTGACAATATGTTCCAGTTGT 0 false Homo sapiens OREG0000059 AP1 (Jun family) CRE AP1 (Jun family) CRE USER DEFINED TRANSCRIPTION FACTOR BINDING SITE 16-Aug-2005 16-Aug-2005 OREGEC00000 OREGES00000 OREGET00000 smontgom ENSG00000092969 TGF-beta 2 (transforming growth factor b ENSEMBL homo_sapiens_core_32_35a 61 POSITIVE OUTCOME 15647279 0 sequence_with_flank EMPTY 0 false 0 sequence AGTTCAGATCCGCCACTCCGCACCCGAGACTGACACACTGAACTCCAC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000060 REGULATORY REGION 16-Aug-2005 16-Aug-2005 OREGEC00000 OREGES00000 OREGET00000 smontgom ENSG00000092969 TGF-beta 2 (transforming growth factor b ENSEMBL homo_sapiens_core_32_35a 62 POSITIVE OUTCOME 15647279 0 sequence_with_flank EMPTY 0 false 0 sequence CAAGCAGGATACGTTTTTCTGTTGGGCATTGACTAGATTGTTTGCAAAAG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000061 REGULATORY REGION 16-Aug-2005 16-Aug-2005 OREGEC00000 OREGES00000 OREGET00000 smontgom ENSG00000092969 TGF-beta 2 (transforming growth factor b ENSEMBL homo_sapiens_core_32_35a 63 POSITIVE OUTCOME 15647279 0 sequence_with_flank EMPTY 0 false 0 sequence ATTTTTTTCTTCTTACTCGCCAAAGTCAGGGTTC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000062 REGULATORY REGION 16-Aug-2005 16-Aug-2005 OREGEC00000 OREGES00000 OREGET00000 smontgom ENSG00000092969 TGF-beta 2 (transforming growth factor b ENSEMBL homo_sapiens_core_32_35a 64 POSITIVE OUTCOME 15647279 0 sequence_with_flank EMPTY 0 false 0 sequence AATATTTCCACTTTTGGAACTACTGGCCTTTTCTTTTTAAAGGAATT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000063 REGULATORY REGION 16-Aug-2005 16-Aug-2005 OREGEC00000 OREGES00000 OREGET00000 smontgom ENSG00000023287 RB1 ENSEMBL homo_sapiens_core_32_35a 65 POSITIVE OUTCOME 15618023 0 sequence_with_flank EMPTY 0 false 0 sequence GGCGGAAGT 0 false 0 sequence_with_flank ttccccacagacgccggcgggcccgggagcctcgcggacgtgacgccgcgGGCGGAAGTgacgttttcccgcggttggacgcggcgctcagttgccgggcg 0 false Homo sapiens OREG0000064 E4TF1, Fli-1 (RBF Motif) E4TF1, Fli-1 (RBF Motif) USER DEFINED TRANSCRIPTION FACTOR BINDING SITE 16-Aug-2005 16-Aug-2005 OREGEC00000 OREGES00000 OREGET00000 smontgom ENSG00000023287 RB1 ENSEMBL homo_sapiens_core_32_35a 66 POSITIVE OUTCOME 15618023 0 sequence_with_flank EMPTY 0 false 0 sequence CGGGCGG 0 false 0 sequence_with_flank agttccccacagacgccggcgggcccgggagcctcgcggacgtgacgccgCGGGCGGaagtgacgttttcccgcggttggacgcggcgctcagttgccggg 0 false Homo sapiens OREG0000065 ENSG00000185591 Sp1 ENSEMBL homo_sapiens_core_32_35a TRANSCRIPTION FACTOR BINDING SITE 16-Aug-2005 16-Aug-2005 OREGEC00000 OREGES00000 OREGET00000 smontgom ENSG00000023287 RB1 ENSEMBL homo_sapiens_core_32_35a 67 POSITIVE OUTCOME 15618023 0 sequence_with_flank EMPTY 0 false 0 sequence CGGGCGGGGGA 0 false 0 sequence_with_flank ccgcgggcggaagtgacgttttcccgcggttggacgcggcgctcagttgcCGGGCGGGGGAgggcgcgtccggtttttctcaggggacgttgaaattattt 0 false Homo sapiens OREG0000066 ENSG00000185591 Sp1 ENSEMBL homo_sapiens_core_32_35a TRANSCRIPTION FACTOR BINDING SITE 16-Aug-2005 16-Aug-2005 OREGEC00000 OREGES00000 OREGET00000 smontgom ENSG00000023287 RB1 ENSEMBL homo_sapiens_core_32_35a 68 POSITIVE OUTCOME 15618023 0 sequence_with_flank EMPTY 0 false 0 sequence GGAAGTGACG 0 false 0 sequence_with_flank cccacagacgccggcgggcccgggagcctcgcggacgtgacgccgcgggcGGAAGTGACGttttcccgcggttggacgcggcgctcagttgccgggcgggg 0 false Homo sapiens OREG0000067 ENSG00000141510 p53(TP53) ENSEMBL homo_sapiens_core_32_35a TRANSCRIPTION FACTOR BINDING SITE 16-Aug-2005 16-Aug-2005 OREGEC00000 OREGES00000 OREGET00000 smontgom ENSG00000023287 RB1 ENSEMBL homo_sapiens_core_32_35a 69 POSITIVE OUTCOME 15618023 0 sequence_with_flank EMPTY 0 false 0 sequence GTGACGTTT 0 false 0 sequence_with_flank cagacgccggcgggcccgggagcctcgcggacgtgacgccgcgggcggaaGTGACGTTTtcccgcggttggacgcggcgctcagttgccgggcgggggagg 0 false Homo sapiens OREG0000068 ENSG00000115966 ATF-2 ENSEMBL homo_sapiens_core_32_35a TRANSCRIPTION FACTOR BINDING SITE 16-Aug-2005 16-Aug-2005 OREGEC00000 OREGES00000 OREGET00000 smontgom ENSG00000023287 RB1 ENSEMBL homo_sapiens_core_32_35a 70 POSITIVE OUTCOME 15618023 0 sequence_with_flank EMPTY 0 false 0 sequence TTTCCCGC 0 false 0 sequence_with_flank cggcgggcccgggagcctcgcggacgtgacgccgcgggcggaagtgacgtTTTCCCGCggttggacgcggcgctcagttgccgggcgggggagggcgcgtc 0 false Homo sapiens OREG0000069 ENSG00000101412 E2F-1 (E2F1) ENSEMBL homo_sapiens_core_32_35a TRANSCRIPTION FACTOR BINDING SITE 16-Aug-2005 16-Aug-2005 OREGEC00000 OREGES00000 OREGET00000 smontgom ENSG00000023287 RB1 ENSEMBL homo_sapiens_core_32_35a 71 POSITIVE OUTCOME 15618023 0 sequence_with_flank EMPTY 0 false 0 sequence AGAGGACGGGGCGTGCCCCGACGTG 0 false 0 sequence_with_flank tccggtttttctcaggggacgttgaaattatttttgtaacgggagtcgggAGAGGACGGGGCGTGCCCCGACGTGcgcgcgcgtcgtcctccccggcgctc 0 false Homo sapiens OREG0000070 ENSG00000141510 p53(TP53) ENSEMBL homo_sapiens_core_32_35a TRANSCRIPTION FACTOR BINDING SITE Designated a low-penetrance allele by authors. 30-Sep-2005 smontgom 30-Sep-2005 The annotated variant allele has lower protein binding affinity (A allele). 30-Sep-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Cell-lines: MCF-7 and HepG2. In MCF-7, 1.9 fold higher expression for reference allele (G allele). In HepG2, this is 1.4 fold higher. (From 1999 study by same author) 30-Sep-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 1576 CYP3A4 NCBI 72 POSITIVE OUTCOME 14673875 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000071 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 30-Sep-2005 0 reference_sequence agacaagggcaGgagagaggc 0 false rs2740574 dbSNP GERMLINE 0 variant_sequence agacaagggcaAgagagaggc 0 false The mutation is present in the canonical genome sequence it is A(T)10AT. 30-Sep-2005 smontgom Record represents a deletion. The variant sequence is present in hg18, while the reference sequence with a deletion represents that changed sequence. 26-Apr-2007 bcb 30-Sep-2005 Allele frequence in 87 Japanese (60%), 50 Caucasion (39%), and African-American (44%). The mutation is present in the canonical genome sequence it is A(T)10AT. 30-Sep-2005 OREGEC00000 OREGES00011 OREGET00006 smontgom Cell line: HepG2 (human hepatoblastoma). Variant allele A(T)10AT has 2.6-fold more activity than reference A(T)9AT allele. 30-Sep-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 54600 UGT1A9 NCBI 73 POSITIVE OUTCOME 15115919 0 search_space CTCATATATTCTTGTTCTTTTGGGTAAATCATTGTCAGTGACTGATTTTTTTTTTATGAAAGGATAAAAACACGCCCTCTATTGGGGTCAGGTTTTGTGCTGGTATTTCTCCCACCTACTGTATCATAGGAGCTTAGATTCCCAGCTGCTTGCTCTCAGCTGCAGTTCTCTG 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000072 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 30-Sep-2005 0 reference_sequence tcattgtcagtgactgatttttttttatgaaaggataa 0 false rs3832043 dbSNP GERMLINE 0 variant_sequence tcattgtcagtgactgatttttttttTatgaaaggataa 0 false EMSA test was also performed but the annotated polymorphism did not alter binding of nuclear factors. 30-Sep-2005 smontgom 30-Sep-2005 In MC and C2C12 cell lines, activity with G allele was 1.4-fold higher than activity with C allele. 30-Sep-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 2673 GFPT1 NCBI 74 NEUTRAL OUTCOME 15878746 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000073 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 30-Sep-2005 0 reference_sequence cttaatcatataaCcagccatagaa 0 false GERMLINE 0 variant_sequence cttaatcatataaGcagccatagaa 0 false Retested in 93 samples for serum resistin levels. G/G genotype had higher serum resistin levels than C/C. 30-Sep-2005 smontgom 30-Sep-2005 Nuclear proteins bound to the G allele but not to the C allele. A competitor to G when added in excess competed out binding. Cell line: 3T3-L1 adipocytes. 30-Sep-2005 OREGEC00001 OREGES00003 OREGET00001 smontgom Identified polymorphism by resequencing ~1kb upstream of 24 Japanese patients with T2DM (Type 2 Diabetes Mellitus). 30-Sep-2005 OREGEC00000 OREGES00010 OREGET00006 smontgom Antibodies to Sp1 weakly affected protein binding. Antibodies to Sp3 strongly affected protein binding. Together, the complex was entirely supershifted. 30-Sep-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom 3-fold).]]> 30-Sep-2005 OREGEC00002 OREGES00004 OREGET00002 smontgom 56729 RETN NCBI 76 POSITIVE OUTCOME 15338456 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000075 Sp1 / Sp3 Sp1 / Sp3 USER DEFINED REGULATORY POLYMORPHISM 30-Sep-2005 0 reference_sequence ccttcccacttccaacagggcctccGtcttcatgtccagagactggtcagg 0 false rs1862513 dbSNP GERMLINE 0 variant_sequence ccttcccacttccaacagggcctccCtcttcatgtccagagactggtcagg 0 false The binding activity was constitutive as EMSA signal intensities not affected by clobetasol propionate or Terbutalin. AP-2 was tested in complex but was not the causal transcription factor for differential expression. 30-Sep-2005 smontgom 30-Sep-2005 17-18% reduction in transcription from the C allele as compared to the T allele 30-Sep-2005 OREGEC00000 OREGES00009 OREGET00004 smontgom One of the complexes shifted with the T allele was less abundant than a complex shifted with the C allele. 30-Sep-2005 OREGEC00000 OREGES00001 OREGET00001 smontgom 154 ADRB2 NCBI 77 POSITIVE OUTCOME 15578262 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000076 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 30-Sep-2005 0 reference_sequence ccgcccgggccagccCcaggagaaggaggg 0 false rs11959427 dbSNP GERMLINE 0 variant_sequence ccgcccgggccagccTcaggagaaggaggg 0 false Search space sequence is the targetted EMSA sequence. 1-Oct-2005 smontgom 1-Oct-2005 Cell lines: MDA-MB-231, MCF-7, HEK-293, and SL-2. SL-2 line is Sp-1 deficient; demonstrated ~100-fold induction when contransfected with Sp1; EGFR expression dependent on Sp1. Lower promoter activity observed with G allele compared to T allele. 1-Oct-2005 OREGEC00002 OREGES00004 OREGET00002 smontgom Cell line: MDA-MB-231. Affinity of nuclear proteins to T allele was higher than G allele. Assay with pure Sp1 demonstrated similar results. 1-Oct-2005 OREGEC00002 OREGES00001 OREGET00001 smontgom Cell type: Human fibroblast cells. EGFR mRNA (using 10 cell lines with diplotype G-C/T-C) was ~40% higher with T allele than G allele. (In vivo assay) 1-Oct-2005 OREGEC00001 OREGES00009 OREGET00004 smontgom 1956 EGFR NCBI 78 POSITIVE OUTCOME 15665278 0 search_space gcagcctccgccccccgcacggtgt 0 false 0 sequence cctccgcccc 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000087 6667 SP1 NCBI REGULATORY POLYMORPHISM 1-Oct-2005 0 reference_sequence ccgcagcagcctccGccccccgcacg 0 false rs712829 dbSNP GERMLINE 0 variant_sequence ccgcagcagcctccTccccccgcacg 0 false 1-Oct-2005 Protein bound with higher affinity to T allele than G allele and was competed out with excess unlabelled T-probe. 1-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Pre-incubation with antibody to Sp1 removed formation of complex. 1-Oct-2005 OREGEC00002 OREGES00001 OREGET00001 smontgom Cell line: Human myeloid leukaemia premonocyte cell line: THP-1. Comparison of promoter activity show greater activity with T allele than G allele (D compared with F haplotype in reference) 1-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 6696 SPP1 NCBI 79 POSITIVE OUTCOME 16009426 0 search_space CATCTAGAATAAATTACCATTCTTCTATTTCATATAGAATTTTATATTTTAATGTCACTAGTGCCATTTGTCTAAGTAACAAGCTACTGCATACTCGAAATCACAAAGCTAAGCTTGAGTAGTAAAGGACAGAGGCAAGTTTTCTGAACTCCTTGCAGGCTTGAACAATAGCCTTCTGGCTCTTCAATAAGTACAATCATACAGGCAAGAGTGGTTGCAGATATTACCTTTATGTTACTTAAACCGAAAGAAACAAAAATCCATTCTATTTAATTTTACATTAATGTTTTTCCCTACTTTCTCCCTTTTTCATGGGATCCCTAAGTGCTCTTCCTGGATGCTGAATGCCCATCCCGTAAATGAAAAAGCTAGTTAATGATATTGTACATAAGTAATGTTTTAACTGTAGATTGTGTGTGTGCGTTTTTGTTTTTTTTTGTTTTAACCACAAAACCAGAGGGGGAAGTGTGGGAGCAGGTGGGCTGGGCAGTGGCAGAAAACCTCATGACACAATCTCTCCGCCTCCCTGTGTTGGTGGAGGATGTCTGCAGCAGCATTTAAATTCTGGGAGGGCTTGGTTGTCAGCAGCAGCAGGAGGAGGCAGAGCACAGCATCGTCGGGACCAGACTCGTCTCAGGCCAGTTGCAGCCTTCTCAGCCAAACGCCGACCAAGGTACAGCTTCAGTTTGCTACTGGGTTGTGCAT 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000088 6667 SP1 NCBI REGULATORY POLYMORPHISM 1-Oct-2005 0 reference_sequence atgacacaatctcTccgcctccctgtg 0 false GERMLINE 0 variant_sequence atgacacaatctcGccgcctccctgtg 0 false Association studies performed. 1-Oct-2005 smontgom 1-Oct-2005 Cell line: COS-1 cells. A allele demonstrated two-fold decrease in promoter activity compared to C allele. 1-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom Mutant allele (A) showed little or no binding to (mouse) liver nuclear proteins and separately, weakly bound purified TFIID. C allele showed binding of both liver nuclear proteins and purified TFIID (separately) 1-Oct-2005 OREGEC00002 OREGES00001 OREGET00001 smontgom 350 APOH NCBI 80 POSITIVE OUTCOME 12605674 0 search_space CCAAGACATATTAAGAATGGATGAGGAGGACTTTGTATTGATCTGACGTAAGAGAAGATAGAGAATTCAAGGATAGCTCTAAGGTCCTAACTGGAGCTATAGGAGCTTGCAAGAGAGGATGTTGAGCTCAGTTTGTAGGGAATTAAAGTTGTAAGTGCCTCCTGGAAGACATTCTTTGTAATTATACATCTGAAAACTGGAACATCATTTTAGAGAGGTGGAGACTGAGAACAGAGAGTAGGTGTTTGTCCAAAGTTTATATGCCAAGGCTGTGAGTGAAACAGGAGCTTCGATCTTTTGGTGTTCCATCTACAACATACACAAAACAAAAGATGGAGAATGAGAAGTCCAGGCAACCCCGGAAACAACAAGTTTCTGTCAAAAGCAATAATGAACTGTTTTGTGCCATTAACAAAAACGTTATGAAGACAGAAACCATCTCCCAAAGATTTCATAACAGAGCCACATAAGTGGAAAGTAAATGATTAAAGAATGTGGGTCTCAGAGTTCCATTCAAATCATGATACTTTATCTTCTATTTACAAAGATAAAAGTACACCAGAAAATGGTTAATGTTTAAGCGCTTTCATATTTGGCTCTGTCTTTTTAGCAGACGAAAACCACTTTGGTAGTGCCAGTGTGACTCATCCACAATGATTTCTCCAGTGCTCATCTTGTTCTCGAGTTTTCTCTGCC 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000089 TFIID TFIID USER DEFINED REGULATORY POLYMORPHISM 1-Oct-2005 0 reference_sequence ctgtctttttagcagacgaaaacCactttggtagtgccagtgt 0 false rs8178822 dbSNP GERMLINE 0 variant_sequence ctgtctttttagcagacgaaaacAactttggtagtgccagtgt 0 false Polymorphism identified to increase transcription of CD14 by lowering the affinity of the CD14 regulatory region for Sp3 (inhibitory factor). 1-Oct-2005 smontgom 1-Oct-2005 Cell line: Mono Mac 6 cells. C allele had strong basal transcription activity. T allele resulted in 32% increase in gene expression 1-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom Tested Sp and AP2 oligonucleotides. Sp family oligonucleotides competed out binding. Similar results with HeLa nuclear extracts (competed out by Sp family oligonucleotides). Mutation tests showed polymorphism affected affinity for Sp family binding. 1-Oct-2005 OREGEC00002 OREGES00003 OREGET00001 smontgom Tested with antibodies to Sp1, Sp2, and Sp3 successfully. 1-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom 929 CD14 NCBI 81 POSITIVE OUTCOME 11698458 0 search_space GGCGCCTGAGTCATCAGGACACTGCCAGGAGACACAGAACCCTAGATGCCCTGCAGAATCCTTCCTGTTACGGTCCCCCTCCCTGAAACATCCTTCATTGCAATATTTCCAGGAAAGGAAGGGGGCTGGCTCGGAGGAAGAGAGGTGGGGAGGTGATCAGGGTTCACAGAGGAGGGAACTGAATGACATCCCAGGATTACATAAACTGTCAGAGGCAGCCGAAGAGTTCACAAGTGTGAAGCCTGGAAGCCGGCGGGTGCCGCTGTGTAGGAAAGAAGCTAAAGCACTTCCAGAGCCTGTCCGG 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000090 Sp1 / Sp2 / Sp3 (Sp family) Sp1 / Sp2 / Sp3 (Sp family) USER DEFINED REGULATORY POLYMORPHISM 1-Oct-2005 0 reference_sequence cttcctgttacggTccccctccctgaaacatc 0 false rs2569190 dbSNP GERMLINE 0 variant_sequence cttcctgttacggCccccctccctgaaacatc 0 false 2-Oct-2005 Leptin serum levels 50% higher than in AA than GA/GG genotypes. Two-fold increase in adipose tissue leptin secretion by AA vs GA/GG subjects. Population: 39 healthy female swedish subjects (10 GG, 18 GA, 11 AA) 2-Oct-2005 OREGEC00000 OREGES00010 OREGET00006 smontgom Cell line: U937 and subcutaneous adipocytes. Nuclear factors bound with higher affinity to A allele. Probe used is annotated as search space sequence. One protein complex formed in U937 cells as opposed to two in human adipose tissue. 2-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom 3952 LEP NCBI 82 POSITIVE OUTCOME 12189581 0 search_space GCGACAGGGTTGCGCTGATCCTCC 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000091 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 2-Oct-2005 0 reference_sequence tattcttcttttgttttgttttgcgacagggttgcGctgatcctcccgcctc 0 false rs7799039 dbSNP GERMLINE 0 variant_sequence tattcttcttttgttttgttttgcgacagggttgcActgatcctcccgcctc 0 false Flow cytometry showed a higher expression of human alpha-chain on plasmid carrying T allele. 2-Oct-2005 smontgom 2-Oct-2005 Cell line: PT18, and RBL-2H3. Luciferase activity higher from T allele than C allele (construct annotated as search space sequence). Similar results observed in KU812 cell line. 2-Oct-2005 OREGEC00000 OREGES00004 OREGET00002 smontgom Performed with overproduced GATA-1. T allele activity was ~4-fold higher than C allele (increased only 2-fold from previous assay). T allele responded better to GATA-1. 2-Oct-2005 OREGEC00002 OREGES00004 OREGET00002 smontgom Tested specific binding for GATA-1. GATA-1 bound T allele at lower potential than canonical binding sequence. Had two times greater affinity than C allele for GATA-1. 2-Oct-2005 OREGEC00002 OREGES00001 OREGET00001 smontgom Resequenced 54 Japanese individuals. 96.2% of patients with atopic dermititis had T/T/ genotype 2-Oct-2005 OREGEC00000 OREGES00010 OREGET00006 smontgom 2205 FCER1A NCBI 83 POSITIVE OUTCOME 12902495 0 search_space GCTAGCCATGCTCCTGAATATGTATAAACAGTACATCATATGACTAAGAGTTTGACTTAGGGGTTAGATTTTATGTGTTTGAACCCCAAATTAGTTATTTAATAGTTGGCACCCCAAAACAAGTTACTTAACCTCACTAAGATTCAGTTTTCCTGTTTATAAAATGTAGATAGTGATAGTATGTACTTTATAGGATTATTGTGAAAAATAAATGAAATATCAGATTTATTTAGGATAACACCTGGCATATGTTTGGTATTCAGTAATTAGTTGCTGCTGTTTTATTCTGCTCTCCCTTGCATCCCACTTTTCTAAGTTGTAAACTAAATAGTTGTACACAGATTGACAGATTAAGAAAGGCTTGTGATTGTGCTAGACCTATGCCTCTCTCTCACCAGATTCCAGGTGTATATGTGGAGGTGGGATAGGGAGTGGAGTAAGTGGGTAAATATTAAATTGCCCAGTTGGGCACCATCCTGAATATTATCTCTAAAGAAAGAAGCAAAACCAGGCACAGCTGATGGGTTAACCAGATATGATACAGAAAACATTTCCTTCTGCTTTTTGGTTTTAAGCCTATATTTGAAGCCTTAGATCTCTCCAGCACAGTAAGCACCAGGAGTCCATGAAGAAGA 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000092 2623 GATA1 NCBI REGULATORY POLYMORPHISM 2-Oct-2005 0 reference_sequence agctgatgggttaaccagatatgaTacagaaaacattt 0 false rs2251746 dbSNP GERMLINE 0 variant_sequence agctgatgggttaaccagatatgaCacagaaaacattt 0 false Authors noted variant causes new CCAAT box in mutant sequence. Mutation detected from 2 Chinese Type 2 diabetes mellitus patients. 2-Oct-2005 smontgom 2-Oct-2005 HeLa cells transfected. C allele had higher activity (15.7% +/- 4.1%) than A allele (5.7% +/- 2.9%). Used B-Gal assay. 2-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom T had slower shift mobility that WT C allele. Authors suggested role as possible repressor. 2-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom 231 AKR1B1 NCBI 84 POSITIVE OUTCOME 14515207 0 search_space CGCTAAAGCATTCGCTTTCCCACCAGATACAGCAGCTGAGGAACTCCTTTCTGCCACGCGGGGCGCGGGCGAGCGTTGGGGGCGGAAAGAATCCGCTGCCACTAGGACCAGGCGGAAGAAGCATCCCCGCCGACCCTTGGGGAAGGCCGCCGCGGCACCCCCAGCGCAACCAATCAGAAGGCTCCTTCGCGCAGCGGCGCGCCAACCGCAGGCGCCCTTTCTGCCGACCTCACGGGCTATTTAAAGGTACGCGCCGCGGCCAAGGCCGCACCGTACTGGGCGGGGGTCTGGGGAGCGCAGCAGCCAT 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000093 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 2-Oct-2005 0 reference_sequence cggaaagaatccgctgccaCtaggaccaggcggaaga 0 false GERMLINE 0 variant_sequence cggaaagaatccgctgccaAtaggaccaggcggaaga 0 false 2-Oct-2005 Cell lines: Calu-3, CF-PAC1, and HeLa. A allele had increased promoter activity by 60%, 66%, and 45% in the respective cell types. 2-Oct-2005 OREGEC00000 OREGES00004 OREGET00002 smontgom Oligonucleotides assayed harboring various cis-acting consensus sequences. Minimal promoter may act with SRF-like protein. 2-Oct-2005 OREGEC00002 OREGES00001 OREGET00001 smontgom Tested SRF-1 and YY1 protein. Factors could both occupy variant binding region. 2-Oct-2005 OREGEC00002 OREGES00003 OREGET00001 smontgom Supershift against transcription factors binding YY1 and CArG sites. Supershifted YY1 not SRF1 2-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom 1080 CFTR NCBI 85 POSITIVE OUTCOME 10652351 0 search_space GGCTGGGAGTCAGAATCGGGAAAGGGAGGTGCGGGGCGGCGAGGGAGCGAAGGAGGAGAGGAGGAAGGAGCGGGAGGGGTGCTGGCGGGGGTGCGTAGTGGGTGGAGAAAGCCGCTAGAGCAAATTTGGGGCCGGACCAGGCAGCACTCGGCTTTTAACCTGGGCAGTGAAGGCGGGGGAAAGAGCAAAAGGAAGGGGTGGTGTGCGGAGTAGGGGTGGGTGGGGGGAATTGGAAGCAAATGACATCACAGCAGGTCAGAGAAAAAGGGTTGAGCGGCAGGCACCCAGAGTAGTAGGTCTTTGGCATTAGGAGCTTGAGCCCAGACGGCCCTAGCAGGGACCCCAGCGCCCGAGAGACCATGC 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000094 7528 YY1 NCBI REGULATORY POLYMORPHISM 2-Oct-2005 0 reference_sequence gaaagccgctagagcaaatTtggggccggaccaggcagc 0 false GERMLINE 0 variant_sequence gaaagccgctagagcaaatAtggggccggaccaggcagc 0 false 3-Oct-2005 Cell line: MIN6. A allele showed a doubling of IAPP promoter activity compared to G allele. Effect demonstrated on basal transcription. 3-Oct-2005 OREGEC00000 OREGES00004 OREGET00002 smontgom No binding in G allele. Binding detected in A allele. 3-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Tested CRE, TTF-2, AP-1, GRE, and HNF3 oligonucleotides. Competition detected with CRE. Slight competition detected with TTF-2. 3-Oct-2005 OREGEC00002 OREGES00003 OREGET00001 smontgom anti-CREB, anti-CREM, and anti-CBP tested. Supershifted with anti-CREB. CREB peptide addition abolished complex. 3-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom 3375 IAPP NCBI 86 POSITIVE OUTCOME 15243700 0 search_space ACTTCTGCTGTGTATGACACACCATTAACTGCACAAGGACACTGTGTATTTGCTACGTTAATATTTACTGATGAGTTAATGTAATAATGACCCATCCGCTTCTGCTGCCTGTGAGGTACTTTCTATCTATAGGGATGGAAATTAATGACAGAGGCTCTCTGAGCTGCCTGATGTCAGAGCTGAGAAAGGTGTGAGGGGTATATAAGAGCTGGATTACTAGTTAGCAAATGAGGGGGTAAATATTCCAGTGGATACAAGCTTGGACTCTTTTCTTGAAGCTTTCTTTCTATCAGAAGCATTTGCTGATATTGCTGACATTGAAACATTAAAAGGTAAAGAATTTCCTATTTCTGGGAAAGTTTTATTTATTTAGAGAAATGCACACTTGGTGTTAAATTCATGGTTTATTTCAAAGAAAGGCTAAAGGGAGAATGTATTACAATATAAATGTTCAGATTGCTTAGAGAAGGAAATTGGGAAAGTAAAAATCTCGAAATTACTTGAAAAGTGGACAATATTAAGGGACTGTATCAATAAAAATTTTGATCCTTGTAAATTACGTTTTAAAAAGATGTTTCTTTTAAAAACTAAGCTCTAATTTAAAATTACATCAATTAGAACTGTAAGAAATCTCTTGATTTCAGTGCTGGATTATTCTTTGCAGAAAATTTGAGAAGCAATGGGCATCC 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000095 1385 CREB1 NCBI REGULATORY POLYMORPHISM 3-Oct-2005 0 reference_sequence tgacccatccGcttctgctgc 0 false rs11836625 dbSNP GERMLINE 0 variant_sequence tgacccatccActtctgctgc 0 false It was indeterminate as to whether this polymorphism caused a measurable change in transcription. It is suggested that it is not the causal polymorphism for lactase activity but may have some degree of association to the timing of downregulation of this gene among children. 3-Oct-2005 smontgom 3-Oct-2005 3-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom 3938 LCT NCBI 87 POSITIVE OUTCOME 10573012 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000096 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 3-Oct-2005 0 reference_sequence tttttcatagatgtttcCatattgtttga 0 false GERMLINE 0 variant_sequence tttttcatagatgtttcTatattgtttga 0 false 3-Oct-2005 261 Japanese women subject. 82 had G allel, 48 had A allele, 131 were heterzygotic. Bone mineral density (BMD) was 12% lower in lumbar spine (L2-L4) with the G allele compared to the C allele. 3-Oct-2005 OREGEC00000 OREGES00010 OREGET00006 smontgom G inhibition of binding weaker than A inhibition of binding in competition. 3-Oct-2005 OREGEC00001 OREGES00003 OREGET00001 smontgom Cell line: Caco-2. G allele activation was 30% less than A allele (with TK promoter fused to Cdx-2). G allele activation was 15% less than A allele (with native hVDR promoter) 3-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 7421 VDR NCBI 88 POSITIVE OUTCOME 11450701 0 sequence_with_flank EMPTY 0 false 0 sequence GTAAAAACTTAT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000097 1045 CDX2 NCBI REGULATORY POLYMORPHISM 3-Oct-2005 0 reference_sequence taggtcacaGtaaaaacttatttcttatt 0 false rs11568820 dbSNP GERMLINE 0 variant_sequence taggtcacaAtaaaaacttatttcttatt 0 false 4-Oct-2005 Cell line: HeLa (nuclear extracts). Both shifted by nuclear extracts. Binding greater in G allele than A allele. Both less than canonical AP2 binding site. Specific for AP2, unlabelled SP1 failed to exhibit this effect. 4-Oct-2005 OREGEC00002 OREGES00001 OREGET00001 smontgom A allele associated on haplotype more common in responder group. Direct association found with response to fluoxetine in response vs nonresponse. 4-Oct-2005 OREGEC00000 OREGES00010 OREGET00006 smontgom 6532 SLC6A4 NCBI 242 POSITIVE OUTCOME 15993855 0 search_space GCATCCCCCCTGCACCCCCAGCATCCCC 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000313 7020 TFAP2A NCBI REGULATORY POLYMORPHISM 4-Oct-2005 0 reference_sequence gcatcccccctgcacccccAgcatcccc 0 false rs25531 dbSNP GERMLINE 0 variant_sequence gcatcccccctgcacccccGgcatcccc 0 false Polymorphism nt is conserved only between human and chimp (against human, mouse, rat, dog, chimp comparison). 4-Oct-2005 smontgom 4-Oct-2005 Cell line: HepG2 - HB8065. -571 to +56 construct showed T allele decrease reported gene transcription by 38% (construct was extracted from patient with T allele). 4-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom Complexes formed with T allele less intense than C allele constructs. (Both constructs, noted in search space sequence, bound complexes) 4-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Addition of YY1 antibody removed complex 2 formation. 4-Oct-2005 OREGEC00002 OREGES00001 OREGET00001 smontgom 6949 TCOF1 NCBI 243 POSITIVE OUTCOME 16102917 0 search_space atctgctggagatgagtaaaacgcagacccagccatcagagaattaacaag 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000314 7528 YY1 NCBI REGULATORY POLYMORPHISM 4-Oct-2005 0 reference_sequence gagttcagagatgagtaaaacgcagaccCagccatcagagaattaacaag 0 false GERMLINE 0 variant_sequence gagttcagagatgagtaaaacgcagaccTagccatcagagaattaacaag 0 false Tested GATA-1, -4, -6, Oct-1, HNF-3gamma, HNF-4alpha, RXR-alpha antibodies. No change to EMSA or supershift. 4-Oct-2005 smontgom 4-Oct-2005 Carriers of this polymorphism were associated with higher quinine metabolic ratio (higher CYP3A4 expression). Population: 143 healthy, Tanzanians. 4-Oct-2005 OREGEC00000 OREGES00010 OREGET00006 smontgom Nuclear protein binds in close proximity to this polymorphism and the A allele has higher binding affinity than the G allele. 4-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom 1576 CYP3A4 NCBI 279 POSITIVE OUTCOME 16171783 0 search_space GAGACAAGGGCAGGAGAGAGGCGAT 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000099 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 4-Oct-2005 0 reference_sequence gagacaagggcaAgagagaggcgatttaatagattttatgccaatggctc 0 false rs2740574 dbSNP GERMLINE 0 variant_sequence gagacaagggcaGgagagaggcgatttaatagattttatgccaatggctc 0 false 4-Oct-2005 In 334 case and 375 control individuals. This polymorphism is associated to osteoarthritis. 4-Oct-2005 OREGEC00000 OREGES00010 OREGET00006 smontgom Cell line: OUMS-27 and Huh-7 cells. In both lines, the C allele showed greater than 2 fold activity compared to the T allele. (Search space sequence is -53 to +8 used in minimal construct) 4-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom Cell line: Huh-7. The T allele was more intense than the C allele. (More factors bound to the T allele) 4-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom RNA Difference Plot analysis used in vivo. The T allele showed decrease expression relative to C allele (1.09 difference) 4-Oct-2005 OREGEC00001 OREGES00007 OREGET00004 smontgom 801 CALM1 NCBI 314 POSITIVE OUTCOME 15746150 0 search_space gcgcaccatatatatatcgcggggcgcagactcgcgctccggcagtggtgctgggagtgtcg 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000146 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 4-Oct-2005 0 reference_sequence atatatatcgcggggCgcagactcgcgctcc 0 false rs12885713 dbSNP GERMLINE 0 variant_sequence atatatatcgcggggTgcagactcgcgctcc 0 false Tested supershift with anti-E2F-1 antibody. Results unsuccessful. 5-Oct-2005 smontgom 5-Oct-2005 Population: 42 Aspirin-induced asthma. 361 Childhood asthma; 313 adult atopic asthma; 88 adult non-atopic asthma. Japanese. Increased risk for AIA associated with C allele. 5-Oct-2005 OREGEC00000 OREGES00010 OREGET00006 smontgom Cell line: HEK293 and HeLa cells. Luciferase activity analyzed after 24hr of transfection. C allele had significantly higher activity than T allele (33%-98% increase). 5-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom Cell line: HEK293 and HeLa cells. In HEK293 cells, C allele band more intense than T allele band (21% increase) for nuclear factor complex. Also observed in HeLa cells. 5-Oct-2005 OREGEC00000 OREGES00001 OREGET00001 smontgom 30009 TBX21 NCBI 315 POSITIVE OUTCOME 15806396 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000100 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 5-Oct-2005 0 reference_sequence tgttccttaaggtacggagaaatggTgggtaaggtgttggggagg 0 false rs4794067 dbSNP GERMLINE 0 variant_sequence tgttccttaaggtacggagaaatggCgggtaaggtgttggggagg 0 false 5-Oct-2005 Cell line: K562 cells. DNA-protein complex detected and competed with excess unlabelled WT probe. Excess mutated probe (C allele) failed to compete with binding. SP1 probe was shown to effectively compete binding whereas NFkappaB could not. 5-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Anti-SP1 antibodies supershifted the G allele probe. (anti-SP3 and anti-EKLF antibodies di not supershift) 5-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom B gal plasmid used. Cell line: Jurkat and K562 cells. (Construct region annotated as search space sequence; -759 to +3). In Jurkat line, 40-fold expression difference for WT (G allele). Tested SP1 positively for promoter activity. 5-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 2235 FECH NCBI 316 POSITIVE OUTCOME 15850836 0 search_space GCGGCCTCCCGAGCCCTGAGTGCTGCCCTCAGCCCTCCCTTCTCCGCGACGCCCCTCGCCCGGTTGCTCGCAGCACCCCCAAGGCCGCTCCCCGAATCCCCCGGGCGCGAGGGCCCGGGCGCCAGCTGCCCGCTCTGCCCACGCCTTCTCAGGGATCCTGGCCCTGGCGGCCGCCGCGACAGACCCACTTACGCGGATCGCGGAGCAGGACGCCCGCGGCGCGCAGGGCCGCAGCCATGTTTGCGCCGAGTGAACGCATTGCCTGGGCAGCCTCGGCCCGAGTCCGGGCTCCTCCCGCGGCGGCGCGCCCAGGTGTCCGCCCAGCAGTGGCCGAGCCGGGTAGCGATCCCCACGCGCGTCCCCAGCCCCCTGACCTCGCGCCCTCCCGGCGCGCCCGCTCATTCGCTGCCGGGCCGGGGCGGGCGAGGCCAGGCAGAGACACGCCCCTCGCGGAGAGCCCGCCCCAGCTGGGCGCCGCTCCCTGCGTGAAAATGGGCCCGGGGGCTGAGCTAGAAGCCCGCTCCCCACCACCATCGCAGGTCACTGCAAAACCTGCTGGACTCCTAGTTGCGTGCCCTGTTTGCATCTGCCAAACTAGCGAAGTCAGGATCCTCAGCCATGACTCAGCAAATAACTTTTTTCGACGTTTCCATTACTATTATTTAGATATAAGGATGCTTTTGCCTCAGTTCTCCAGTTTGCCTGCCTAGTCACAACACAAGTGTGCAGATCCTGTTTTGTTTTGCTTTATTTTCAGAATAGA 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000101 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 5-Oct-2005 0 reference_sequence ggggagcgggcttctaGctcagcccccgggcc 0 false GERMLINE 0 variant_sequence ggggagcgggcttctaCctcagcccccgggcc 0 false Polymorphism detected from 98 DNA samples 2.3kb upstream resequencing in Caucasian population. 5-Oct-2005 smontgom 5-Oct-2005 Cell line: HepG2, Rat hepatocyte, Human hepatocyte. Increased promoter activity with C allele. (Construct annotated as search sequence space) 5-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom C allele detected a protein-complex band. T allele did not. Incubated with C/EBP protein. 5-Oct-2005 OREGEC00002 OREGES00001 OREGET00001 smontgom Incubated with TBP. C allele had weaker binding than T allele. Suggesting a TATA box is altered and a C/EBP box is created. 5-Oct-2005 OREGEC00002 OREGES00001 OREGET00001 smontgom Shorter transcripts dominate in C allele compared to T allele (longer transcripts). This is due to increased affinity for the TATA box at the -82 polymorphic site. 5-Oct-2005 OREGEC00002 OREGES00020 OREGET00004 smontgom 1555 CYP2B6 NCBI 317 POSITIVE OUTCOME 15722458 0 search_space TTAATTAGTGGCCACATGCAGCAAGTGACTATCACATTGGACAATGTAGCCCCAACCCACTGTATGACCTTGGGTAAGACTTGCAAACTGTCATTGCTTCAATATCTCCATCTATAAAATGGGGATGGCAACAATACCTCACTAAGAGTGTAAAGACTGAGTTACTGTGTGTAAAGCACTTCACGCCTCCCCATCGGTGCTTCACCCTGGGGCTGCAATGAGCACCCAATCTTAGTGTCAGATGACACAGCACAGCAAGACCGAGGCCCTTGGTTCAGGAAAGTCCATGCTGCCACCTCTTCAGGGTCAGGAAAGTACAGTTTCCACCTCTTACAAATAGGACTGTTTGTCTGCTCCTCCTGGGTCAAAGTAACTTCGGGTTCAGGTCCTGGATCCAGCAAAGGGTTTGCTTAACATTGCAAGAAAGATGTTGCCTCATGGTCAAAAGTCAGGCGTAGGATGAGACAGGCAGACACGCACACATTCACACCCACGTTTTGCAAAGATGGACTGACCCTGTCAGAGGATGTGTGGGTGAAGGTGCACAGTGAGGATAGAGACATATGGGAGTCCAGTAGACATCAATCAAACTGGACTCAGTTTGCACACACCTGGAGCTCAAGAGTCTCCAGGGGGAAAACAGAGACACAAAGTCAGACAGAGAGAGAGCCAGAGAAATTTCCTGCACCGTGAAGATAGTCAGAGGCAGGGAAGAAACTCCTTAGCACTAGTTAGAGTGATCAGAAACCAAGAGGACCTGATCGCTGTACCTGCCAGGTCTCAGTTTCTGTCTCCTTCCAACTGACCACCTCTTCCTCTGAGACTCACCAGTTCTGCATCTCTTGCTCCTCCTTCTGTTTCTCCGACCACTTCCACCTGTGGCTGTCACAGAAGGGCGGATGAAGGAGGGGACACTGGAGATAGACTCAGCATCTGCAGGCTTCCAAAGAGAGGGGCTAGGAGATCCACCAACACACCAGCACAAATACACCAGCACACACAGATACACACAATTGGTTCATGTATTGCTAGGTTACAGTTTGCTATGCTACAAAGGCAGTAGGCCAAATTTGATTGAATTGAATAATTCCTTATTTTCATCAGCTTCTCCTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTATTGCTGTGTCACCCAGGCTGGAGTGCAGTGGTGTAATCTTGGCTCACTGCAGCCTCCACCTCCCAGGTTCAAGTGATTCTCTTGCCTCAGCCTCCCGAGTAGCTGGGATTAAAAGTACCCACCATCACGCCCGGTTAATTTTTGTGTTTTTAGTACAGATGGGGTTTTGCCATGTGGGCCAGGATGGTCTCGAACTCTTGACCTCAATTGATCTGCCCCCCTCAGCTTCCCAACGTGCTGGGATTACAGGTGTGAGCCACCGCACCCAGCCAGCCTCTCAGTTTTGAACATGCACTACCACCACCTCCACAACACACAAATGTAAATGCACTTTCGTATATAAAACTGTATAAATACAAGGAAGCTCATACACATGCAAGGATACACACATAAGCACCCCCAGATTCAACCACAGAAATATACGCCAGTACATTTGCATAAATTCAAACACCCCTTTACATGTAAAAATCATATAAGCACATACAGGGATGCAAGCAGGCATGGACAAATGCATGCAAGCACAGACAAACAGACAAAGCTAAGTAAAAAAGTGCAAGCTCACCTATGCTTACAAAAATAGACATACATATACCCACAAACCCACACACCCACACATTCACTTGCTCACCTGGACTTTGATATCTCTACCACTGTATCCCTGCCAATATCTACAGAGTGGGTAAAGGGATAGGCATCAGGTCACTGGGTTGCCCAAGCAGGAAGTCTGGGTTCCCTAACAACTTTTTCTAAGCTAATGCTCCTGGATGATGATGAAAAAGGAGGTGGGGAATGGATGAAATTTTATAACAGGGTGCAGAGGCAGGGTCAGGATAAAAGGCCCAGTTGGAGGCTGCAGCAGGGTGCAGGGCAGTCAGACCAGGACCATG 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000102 TBP / C-EBP TBP / C-EBP USER DEFINED REGULATORY POLYMORPHISM 5-Oct-2005 0 reference_sequence aggtggggaatggatgaaatttTataacagggtgcagaggcagggtcagg 0 false GERMLINE 0 variant_sequence aggtggggaatggatgaaatttCataacagggtgcagaggcagggtcagg 0 false 5-Oct-2005 Cell line: HeLa and HUVEC. T allele demonstrated weaker shifts than C probe. Competition with unlabelled competitor demonstrated 10-fold greater affinity for C compared to T allele. 5-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Nuclear extracts from HUVECs used. Antibodies for SP1. Sp2, Sp3, and Sp4 used. Supershift of both Sp1 and Sp3 detected. Experiment confirmed in C11STH, HeLa, and NT2 cell lines. 5-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom Search space sequence is the -7137 to -8087 (950bp) construct. Cell line: HeLa. C allele had higher promoter activity for all tested retinoic acid concentrations. 5-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 5327 PLAT NCBI 318 POSITIVE OUTCOME 15466927 0 search_space GACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGAACTCAAGGTATCCGCCTGCCTTGGCCTCCTAAAGTGCTGAGATTACAGGCATGAGCCACTGTGCCCAGCCTACTCCTTATTTTAAATGTGCAAACTCTGCAAAGTGGCTGTGCTGAGGCACTTCCAAATGCCACCCAGGTGGTGCTCAAGCTCTGGTTTCTGCTCTATGAGCCCTTCTTCTTCTGGACCTGGTGCCACCAACCCTTGCAGCCTCCTATGGAGGATGGTGCGTGTTTCCTTTCAGCCTTTCTGGTCATTTCTTTTCTTGTTTTAAAATAACAACACCAGGCCAGGTGAGGTGGCTCACTCCTGTAATCCTAACACTTTGGGAGGCCAAGGTGGGAGGATTCCTTGAGCCCAGAAGTTTGAGACCAGCCTGGGCAACATGGCGAGACCCTATCTCTACAAATAATTAAAAAATTAGTCAGGTGTGGTGGCACATGCATGTAGTCCCAGCTACTTAGGAGGCTGAGGTGGAAGGATCCCTTGAACCTGAAAATTTGAGGTTGCAGTGAACTGTGATCCCATCACTGCACTCCAGCCTGGGAGACAGAGTAAAAGCCTGTCTCTAAAAATAAAAAATAAATAAACACATAAATAACACTGACAATAACCAAAACCAAGTGAATACAGATAATTCCTTCTGACCCCAGGGTGACCCCAGAGTCCCAGGCCATGGCTGTGTCTGGGGCAGGCTCCTTTGGGAGAGCGGCCAAAGCCCTATTCACCTCGGCAATGAGATCACTCAGACCTGGGGGGAGGCGCGTTCTGGGAGAGCGTGGTGACTTCCACAGCAGGGGCTCTTGCATCAGTTCTGGTTACCCACGGGAGACTGCATGTGCTCAGGGTGACAGGAACACCACTGTTTACATGGGACCCACCTCCCGCCATGGCATCACAGGACTCG 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000103 Sp1 / Sp3 Sp1 / Sp3 USER DEFINED REGULATORY POLYMORPHISM 5-Oct-2005 0 reference_sequence gctttggccgctctcccaaaggagccTgccccagacacagccatggcc 0 false rs2020918 dbSNP GERMLINE 0 variant_sequence gctttggccgctctcccaaaggagccCgccccagacacagccatggcc 0 false Identified in 56 Italian individuals. T(0.78)/G(0.22) 5-Oct-2005 smontgom 5-Oct-2005 Cell line: U2OS, COS7, and HeLa cell lines. T allele had higher affinity than G allele. 5-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Supershift removed with addition of anti-Sp1 and anti-Sp3 antibodies. 5-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom (Construct annotated as search sequence space -474 to +42). G allele had lower expression activity. Cotransfection with Sp1 overexpression also demonstrated higher affinity of T allele. 5-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 6696 SPP1 NCBI 319 POSITIVE OUTCOME 15479859 0 search_space TAAGCTTGAGTAGTAAAGGACAGAGGCAAGTTTTCTGAACTCCTTGCAGGCTTGAACAATAGCCTTCTGGCTCTTCAATAAGTACAATCATACAGGCAAGAGTGGTTGCAGATATTACCTTTATGTTACTTAAACCGAAAGAAACAAAAATCCATTCTATTTAATTTTACATTAATGTTTTTCCCTACTTTCTCCCTTTTTCATGGGATCCCTAAGTGCTCTTCCTGGATGCTGAATGCCCATCCCGTAAATGAAAAAGCTAGTTAATGATATTGTACATAAGTAATGTTTTAACTGTAGATTGTGTGTGTGCGTTTTTGTTTTTTTTTGTTTTAACCACAAAACCAGAGGGGGAAGTGTGGGAGCAGGTGGGCTGGGCAGTGGCAGAAAACCTCATGACACAATCTCTCCGCCTCCCTGTGTTGGTGGAGGATGTCTGCAGCAGCATTTAAATTCTGGGAGGGCTTGGTTGTCAGCAGCAGCAGGAGGAGGCAGAGCACAGCATCGTCGGGACCAG 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000104 Sp1 / Sp3 Sp1 / Sp3 USER DEFINED REGULATORY POLYMORPHISM 5-Oct-2005 0 reference_sequence ctcatgacacaatctcTccgcctccctgtgttggt 0 false GERMLINE 0 variant_sequence ctcatgacacaatctcGccgcctccctgtgttggt 0 false Background controlled by using site-directed mutagenesis. 5-Oct-2005 smontgom 5-Oct-2005 5-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 173 bypass patients (GG=115, GC=56, CC=2) vs 454 health caucasian controls. Associated to phenotype: lower CRP levels (C-reactive protein) with C allele. 5-Oct-2005 OREGEC00000 OREGES00011 OREGET00006 smontgom 5743 PTGS2 NCBI 320 POSITIVE OUTCOME 12377741 0 search_space AAGTCGGAGTACTGGGATAGACCCAGGAGGTCAGAGCGGAAACTCTGCCCGGGTGCGTGGAACCGGAGTCCCCGGTGCGCGGCGCCAGGTACTCACCTGTATGGCTGAGCGCCAGGACCGCGCACAGCAGCAGGGCGCGGGCGAGCATCGCAGCGGCGGGCAGGGCGCGGCGCGGGGGTAGGCTTTGCTGTCTGAGGGCGTCTGGCTGTGGAGCTGAAGGAGGCGCTGCTGAGGAGTTCCTGGACGTGCTCCTGACGCTCACTGCAAGTCGTATGACAATTGGTCGCTAACCGAGAGAACCTTCCTTTTTATAAGACTGAAAACCAAGCCCATGTGACGAAATGACTGTTTCTTTCCGCCTTTTCGTACCCCCCACAAATTTTTCCCTCCTCTCCCCTTAAAAAAATTGCGTAAGCCCGGTGGGGGCAGGGTTTTTTACCCACGGAAATGAGAAAATCGGAAACCCAGGAAGCTGCCCCAATTTGGGAGCAGAGGGGGTAGTCCCCACTCTCCTGTCTGATCCCTCCCTCTCCTCCCCGAGTTCCACCGCCCCAGGCGCACAGGTTTCCGCCAGATGTCTTTTCTTCTTCGCAGTCTTTGCCCGAGCGCTTCCGAGAGCCAGTTCTGGACTGATCGCCTTGGATGGGATACCGGGGGAGGGCAGAAGGACACTTGGCTTCCTCTCCAGGAATCTGAGCGGCCCTGAGGTCCGGGGGCGCAGGGAATCCCCTCTCCCGCCGCCGCCGCCGTGTCTGGTCTGTACGTCTTTAGAGGGTCGAGGAAGTCACGTCGGGACAGACTGGGGCGAGTAAGGTTAAGAAAGGCTGACATGTTTTATGTTTTAGTGACGACGCTTAATAGGCTGTATATCTGCTCTATATGCAGCACATACATACATAGCTTTTTAAAAAACTCTTATTTTGTGGAATGAAATAGCTACCTTCAGTGTACATAGCTGTAATTTATCTTTGTAGCTAAGTTGCTTTCAACAGAAGAAATACTGTTCTCCGTACCTTCACCCCCTCCTTGTTTCTTGGAAAGAGAGGCGGGAAAGGTAAATTCTCCTCATAATACTGGTCCTAAGCAGTTACCCTGTAAATAGTTAATGTGAGCTCCACGGGTCACCAATATAAAGTTTCCTGCCTTCTGATGGACAAAGGAAGCGGCGATGGCCAGAATTTGCAGGGACGCTAAATGTCCAAAACGTATGCCTTAAGGCATTTCTCTCCCTGATGCGTGGATTATTTTGGTTACTAGCCCTTCATAGGAGATACTGGTAAAATAAATTCGAGTTTTAAAGTTCACTCTTTTGTCTTTTCTGTCCACTTTTCCAAGATTATGAGTTGTGACCATGGATCAAAGTACAACATAGCATTTACTTTTCAGTTGCCTGGGCTTATTGGGGCTAATTTTCTATTCTCGTTTTGGAACATAGTTGGATGAGGAATTAATTAGATGGAAGGGAGATTTTGACAGTTGGAATTTCATCTTTGCTTTTGTTTAACATCTATCATGGGTAGTGCTCAGGGAGGAGCATGTGAGGGTGAGATACTAAAAAATATATATATGTATATGTGTGTGTGTATATATACATATATATATACACACACACCAGAAAAGAAGTGGAAAATAGAAAATTCAGTTATGTCCTAAGTCCTTAGCATTACAGGAAAATGACAGCATAAAACCTGAAATAAAACTACACCAGGTACCTCAATTTGTAGAAGTCTTATAAGAAAAAAATAAATAAGAGACTCACTTGGAGGTTTTTTTTTTAACTGTTTTGCTTAGTGTACACATCTGATTCTTCATGAGACACGGATGACTAAAATTCCATCTCATCTAGGAAGCCTTTCTCCTCCTCTAGTCATATTTCATCATTCCATTTATGGCACTCCTATTTATTGCATGGAATCTTAC 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000105 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 5-Oct-2005 0 reference_sequence attatgaggagaatttacctttcccGcctctctttccaagaaacaagg 0 false rs20417 dbSNP GERMLINE 0 variant_sequence attatgaggagaatttacctttcccCcctctctttccaagaaacaagg 0 false 5-Oct-2005 Cell line: Jurkat. A allele binds a unique complex compared to G allele. Similar activity tested in Raji, HepG2, HeLa, and U937 cell lines. 5-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Cell line: Jurkat cells. In Jurkat, G allele cause 3 fold repression of SV40 promoter activity. In U937, in double copy, G allele causes 1.95fold enhancement of activity (against control). A allele generally increased transcription 2-fold higher than G allele. Site-directed mutagenesis used to control background. 5-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 7124 TNF NCBI 321 POSITIVE OUTCOME 9293772 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000106 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 5-Oct-2005 0 reference_sequence gttttcaggggcatgGggacggggttcagcctccagggt 0 false rs1800629 dbSNP GERMLINE 0 variant_sequence gttttcaggggcatgAggacggggttcagcctccagggt 0 false This mutation was suggested to counteract the decreased expression effects of a linked (AT)n repeat polymorphism. 6-Oct-2005 smontgom 6-Oct-2005 Cell line: Jurkat, THP-1 cell line. Mutagenesis used to introduce variants into construct (329-bp fragment, genomic DNA). T allele associated with higher activity (8.13 +/ 0.46 vs 6.87 +/- 0.49). 6-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 1493 CTLA4 NCBI 322 POSITIVE OUTCOME 12058260 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000107 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 6-Oct-2005 0 reference_sequence ctccaagtctccacttagttatccagatcctCaaagtgaacatgaagcttcagtttcaaa 0 false rs5742909 dbSNP GERMLINE 0 variant_sequence ctccaagtctccacttagttatccagatcctTaaagtgaacatgaagcttcagtttcaaa 0 false Cross-referenced in rSNP_DB as rSNP00J0001. http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-id+EnIK1R58CA+-e+[rSNP_DB:'rSNP00J0001'] Binding tested as mutually exclusive between HNF-1 and HNF-6. 6-Oct-2005 smontgom 6-Oct-2005 HNF-6 bound DNA. This was competed successfully with probe possessing the canonical HNF-6 binding site. Also tested in Cell line: COS-7. Competed binding of complex with addition of probe possessing the HNF-6 binding site. 6-Oct-2005 OREGEC00002 OREGES00003 OREGET00001 smontgom Supershift of HNF-6 by anti-HNF-6 antibody. 6-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom C allele had reduced affinity for HNF-6 complex. This binding could be competed by T allele. 6-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Cell line: HepG2 and COS-7. C allele had reduced activity and transactivation by HNF-6 was abolished. 6-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 5624 PROC NCBI 323 POSITIVE OUTCOME 9553065 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000108 3175 ONECUT1 NCBI REGULATORY POLYMORPHISM 6-Oct-2005 0 reference_sequence caagcaaatatttgtggttatggaTtaactcgaactccaggctgtcatgg 0 false GERMLINE 0 variant_sequence caagcaaatatttgtggttatggaCtaactcgaactccaggctgtcatgg 0 false Allele was shown to associate to cebral malaria in African population (OR 4.6, 95% CI 1.3-15.7, P=0.016). Cross-referenced in rSNP_DB as rSNP00J0002. http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-id+EnIK1R58CA+-e+[rSNP_DB:'rSNP00J0002'] 6-Oct-2005 smontgom 6-Oct-2005 Cell line: MonoMac6. Detected protected region from -404 to -374 6-Oct-2005 OREGEC00001 OREGES00015 OREGET00003 smontgom Complex binding detected. Was competed only by A allele probe. 6-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Complex formation was inhibited by oligonucleotide probes corresponding to Oct-1 binding site. 6-Oct-2005 OREGEC00002 OREGES00003 OREGET00001 smontgom Supershift with antibodies against Oct-1. 6-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom Cell line: MonoMac6 cells. Used 1.2kb promoter sequence (annotated as search space sequence). Used site-directed mutagenesis to introduce A mutation. A allele showed 35% increase in expression compared to G allele. 6-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 7124 TNF NCBI 324 POSITIVE OUTCOME 10369255 0 search_space GAGGGACAGAGGGCTCAAAGGGAGCAAGAGCTGTGGGGAGAACAAAAGGATAAGGGCTCAGAGAGCTTCAGGGATATGTGATGGACTCACCAGGTGAGGCCGCCAGACTGCTGCAGGGGAAGCAAAGGAGAAGCTGAGAAGATGAAGGAAAAGTCAGGGTCTGGAGGGGCGGGGGTCAGGGAGCTCCTGGGAGATATGGCCACATGTAGCGGCTCTGAGGAATGGGTTACAGGAGACCTCTGGGGAGATGTGACCACAGCAATGGGTAGGAGAATGTCCAGGGCTATGGAAGTCGAGTATGGGGACCCCCCCTTAACGAAGACAGGGCCATGTAGAGGGCCCCAGGGAGTGAAAGAGCCTCCAGGACCTCCAGGTATGGAATACAGGGGACGTTTAAGAAGATATGGCCACACACTGGGGCCCTGAGAAGTGAGAGCTTCATGAAAAAAATCAGGGACCCCAGAGTTCCTTGGAAGCCAAGACTGAAACCAGCATTATGAGTCTCCGGGTCAGAATGAAAGAAGAAGGCCTGCCCCAGTGGGGTCTGTGAATTCCCGGGGGTGATTTCACTCCCCGGGGCTGTCCCAGGCTTGTCCCTGCTACCCCCACCCAGCCTTTCCTGAGGCCTCAAGCCTGCCACCAAGCCCCCAGCTCCTTCTCCCCGCAGGGACCCAAACACAGGCCTCAGGACTCAACACAGCTTTTCCCTCCAACCCCGTTTTCTCTCCCTCAAGGACTCAGCTTTCTGAAGCCCCTCCCAGTTCTAGTTCTATCTTTTTCCTGCATCCTGTCTGGAAGTTAGAAGGAAACAGACCACAGACCTGGTCCCCAAAAGAAATGGAGGCAATAGGTTTTGAGGGGCATGGGGACGGGGTTCAGCCTCCAGGGTCCTACACACAAATCAGTCAGTGGCCCAGAAGACCCCCCTCGGAATCGGAGCAGGGAGGATGGGGAGTGTGAGGGGTATCCTTGATGCTTGTGTGTCCCCAACTTTCCAAATCCCCGCCCCCGCGATGGAGAAGAAACCGAGACAGAAGGTGCAGGGCCCACTACCGCTTCCTCCAGATGAGCTCATGGGTTTCTCCACCAAGGAAGTTTTCCGCTGGTTGAATGATTCTTTCCCCGCCCTCCTCTCGCCCCAGGGACATATAAAGGCAGTTGTTGGCACACCCAGCCAGCAGACGCTCCCTCAGCAAGGACAGCAGAGGACCAGCTAAGAGGGAGAGAAGCAACTACAGACCCCCCCTGAAAACAACCCTCAGACGCCACATCCCCTGACAAGCTGCCAGGCAGG 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000110 5451 POU2F1 NCBI REGULATORY POLYMORPHISM 6-Oct-2005 0 reference_sequence tgaagcccctcccagttctagttctatctttttcctgcatcctgtctggaaGttagaaggaaacagacca 0 false rs1800750 dbSNP GERMLINE 0 variant_sequence tgaagcccctcccagttctagttctatctttttcctgcatcctgtctggaaAttagaaggaaacagacca 0 false rSNP_DB crossreferenced: rSNP00J0003 http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-id+EnIK1R58CA+-e+[rSNP_DB:'rSNP00J0003'] 6-Oct-2005 smontgom 6-Oct-2005 Cell line: HEL cell line. C allele had more CAT activity. In G allele, the activity was reduced by 84% (+/- 13%). (Construct is annotated as search space region). 6-Oct-2005 OREGEC00001 OREGES00019 OREGET00002 smontgom Used 24-mer sequence, TGTGCTATCTGCCGCTGCAGCGCG. Nuclear extracts from CHRF-288, HEL, or HeLa cells. Protein bound to C allele but not G allele. C allele could not be competed off by less than 35-fold excess of unlabelled oligo-nt whereas 1.5-fold excess could compete off G allele. 6-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Supershift detected with monoclonal antibody to GATA-1 not with GATA-2. 6-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom 2812 GP1BB NCBI 361 POSITIVE OUTCOME 8703016 0 search_space TTGTGAATGCCGCGTCCTGTCCTGGTGACAGGAGAACAATGTTGGTGAACGTCGCAGCGGGTGTCCGAGTGCTCCGTGTGCCCCTGAGAGCGGGTGGGAGCGGAAGCCTGAGCGGCCTGCGGCCTCCGGCGATAGTGTGCTATCTGCCGCTGCAGCGCGCGTCCGCGCGGCCTCTGGGCTATTTCTGGCCAGGCCGCAGCACTGTGGTCGGTGCGGGCGTGGCAGGGGCGGGGCGGCCTTATCGCTCGGCTCTCCCGCCTACGCCTCCCGCTGCAGAGTAAGCCGGGCTGCCGTCTTCTCGCCATGGGCTCCGGTGAGTCTGGAGTCCGGTCGGGCCCCCGGCTGCTCCCTAGGCCGACCCGGGTTGAGAGGAGCTCTGGTCGTT 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000363 2623 GATA1 NCBI REGULATORY POLYMORPHISM 6-Oct-2005 0 reference_sequence ccggcgatagtgtgctatCtgccgctgcagcgcgcgtcc 0 false GERMLINE 0 variant_sequence ccggcgatagtgtgctatGtgccgctgcagcgcgcgtcc 0 false This polymorphism is close to rs13434811 which has a reduced yet similar affect on YY1 binding. rSNP_BIB Cross-reference: http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-id+2eRHV1R75Ax+-e+[rSNP_BIB:'RFrSNP0J0004'] 11-Oct-2005 smontgom 11-Oct-2005 Rat liver nuclear extract. A thrid complex binding the oligonucleotide was abated with the A allele compared to the WT G allele. 11-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Tested HNF3, GATA, HNF1, C/EBP, Sp1, AP1, SRE, and ANF. SRE in 40-fold excess competes protein band formation. 11-Oct-2005 OREGEC00002 OREGES00003 OREGET00001 smontgom anti-YY1 causes supershift with protein complex. 11-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom 6999 TDO2 NCBI 393 POSITIVE OUTCOME 10580097 0 search_space TGCCAAATAATGGCAGATAAGAATAGGGAG 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000403 7528 YY1 NCBI REGULATORY POLYMORPHISM 11-Oct-2005 0 reference_sequence ttatatataatgccaaataatgGcagataagaatagggagaaaaagaattacaaagctaa 0 false rs16998970 dbSNP GERMLINE 0 variant_sequence ttatatataatgccaaataatgAcagataagaatagggagaaaaagaattacaaagctaa 0 false This polymorphism is within 3 bases of rs16998970 which has a greater affect on YY1 binding. rSNP_BIB Cross-reference: http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-id+2eRHV1R75Ax+-e+[rSNP_BIB:'RFrSNP0J0004'] 11-Oct-2005 smontgom 11-Oct-2005 Rat liver nuclear extract. A third complex binding the oligonucleotide was decreased with the T allele compared to the WT G allele. 11-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Tested HNF3, GATA, HNF1, C/EBP, Sp1, AP1, SRE, and ANF. SRE in 40-fold excess competes protein band formation. 11-Oct-2005 OREGEC00002 OREGES00003 OREGET00001 smontgom anti-YY1 causes supershift with protein complex. 11-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom 6999 TDO2 NCBI 394 POSITIVE OUTCOME 10580097 0 search_space TGCCAAATAATGGCAGATAAGAATAGGGAG 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000404 7528 YY1 NCBI REGULATORY POLYMORPHISM 11-Oct-2005 0 reference_sequence ttatatataatgccaaataatggcaGataagaatagggagaaaaagaattacaaagctaa 0 false rs13434811 dbSNP GERMLINE 0 variant_sequence ttatatataatgccaaataatggcaTataagaatagggagaaaaagaattacaaagctaa 0 false This was a cuasative allele of HPFH (hereditary persistence of fetal hemoglobin) in a Japanese family based on linkage and resequencing analysis. rSNP_BIB Cross-reference: http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-id+2eRHV1R75Ax+-e+[rSNP_BIB:'RFrSNP0J0006'] 11-Oct-2005 smontgom 11-Oct-2005 Cell line: HeLa, RPMI, K562, KU812, and MEL cells. In all extracts, C allele had two shifted bands, T allele had one. 11-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Competed binding with CP1 oligo-nt. 11-Oct-2005 OREGEC00002 OREGES00003 OREGET00001 smontgom Protection pattern showed that binding of Cp1 is higher affinity to distal CCAAT motif. 11-Oct-2005 OREGEC00001 OREGES00015 OREGET00003 smontgom 3048 HBG2 NCBI 395 POSITIVE OUTCOME 1698280 0 search_space CATGGGTTGGCCAGCCTTGCCTTGACCAATAGCCTTGACAAGGCAAACTTGACCAATAGTCTTAGAGTATCCAGTGAGGCCAGGGGCC 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000405 50820 CP1 NCBI REGULATORY POLYMORPHISM 11-Oct-2005 0 reference_sequence cttccccacactatctcaatgcaaatatctgtctgaaacggtccctggctaaactccacccatgggttggccagccttgccttgacCaatagccttgacaaggcaaacttgaccaatagtcttagagtatccagtgaggccaggggccggcggctggctagggatgaagaataaaaggaagcacccttcagcagttccacacactcgctt 0 false GERMLINE 0 variant_sequence cttccccacactatctcaatgcaaatatctgtctgaaacggtccctggctaaactccacccatgggttggccagccttgccttgacTaatagccttgacaaggcaaacttgaccaatagtcttagagtatccagtgaggccaggggccggcggctggctagggatgaagaataaaaggaagcacccttcagcagttccacacactcgctt 0 false Mutation detected in French-Canadian patient with low-levels of VII:Ag and VII:C. rSNP_BIB Cross-reference: http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-id+2eRHV1R75Ax+-e+[rSNP_BIB:'RFrSNP0J0007'] 11-Oct-2005 smontgom 11-Oct-2005 Cell line: HepG2. Transfected +1 to -185 sequence (annotated as search space sequence). Mutant promoter (G) allele exhibited 5.8 +/- 2.2% of WT promoter activity. 11-Oct-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom Cell line: HeLa. Oligo-used GTGTCCTCCCCTCCCCCATCCCTCT. Binding to SP1 oligo could be competed away with WT oligo but not mutant oligo. 11-Oct-2005 OREGEC00002 OREGES00003 OREGET00001 smontgom 2155 F7 NCBI 396 POSITIVE OUTCOME 9716591 0 search_space AGTGGCTGGGCAGCAGGGGATGCATGGCCACTGGCCGGCCAGGTGCAGCTCTCAGCTGGGGTGTTCAGAGGACGCCTGTGTCCTCCCCTCCCCCATCCCTCTGTCACCCTTGGAGGCAGAGAACTTTGCCCGTCAGTCCCATGGGGAATGTCAACAGGCAGGGGCAGCACTGCAGAGATTTCATCA 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000406 6667 SP1 NCBI REGULATORY POLYMORPHISM 11-Oct-2005 0 reference_sequence gaggacgcctgtgtcctcccctccCccatccctctgtcacccttggaggcagagaacttt 0 false GERMLINE 0 variant_sequence gaggacgcctgtgtcctcccctccGccatccctctgtcacccttggaggcagagaacttt 0 false Tested unsuccessfully, AP1 and NF-E2 as transcription factors. Polymorphism was found in Sardinian pedigree for Delta-thalassemia; was not found in larger population (90 chromosomes). 11-Oct-2005 smontgom 11-Oct-2005 Cell line: HeLa and noninduced and DMSO (dimethyl sulfoxide)-induced K562 cells. Mutant A allele displays higher affinity for erythroid-specific binding. 11-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom 3045 HBD NCBI 397 POSITIVE OUTCOME 1309671 0 search_space CTCTACAGATAGGGAGCA 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000407 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 11-Oct-2005 0 reference_sequence gtaagaaggttcctgaggctctacagataGggagcacttgtttattttacaaagagtacatgggaaaaga 0 false GERMLINE 0 variant_sequence gtaagaaggttcctgaggctctacagataAggagcacttgtttattttacaaagagtacatgggaaaaga 0 false Mutation only detected in 3 Japanese delta-thalassemia patients. Not detected in 58 healthy Japanese. rSNP_Bib Cross-reference: http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-id+2eRHV1R75Ax+-e+[rSNP_BIB:'RFrSNP0M0010'] 11-Oct-2005 smontgom 11-Oct-2005 Cell line: MEL (mouse erythroleukemia). GATA-1 binds to normal (T allele) and mutant (C allele) weakly. This binding was competed out by canonical GATA-1 oligo. WT probe: ATGAAACCCTGCTTATCTTAAACCAACCTG. MT probe: ATGAAACCCTGCTCATCTTAAACCAACCTG 11-Oct-2005 OREGEC00002 OREGES00003 OREGET00001 smontgom 11-Oct-2005 OREGEC00001 OREGES00019 OREGET00002 smontgom 3045 HBD NCBI 398 POSITIVE OUTCOME 1515647 0 search_space TCTGCCCTGCCTTTTATGCTGGTCCTGTCCTCCCTGCTCCAGTGAGCAGGTTGGTTTAAGATAAGCAGGGTTTCATTAGTTTGTGAGAATGAAAAATGAACCTTCATTCCACTATTCCCTTAACTTGCCCTGAGATTGGCTGTTCTGTCATGTGTGTCTTGACTCAGAAACCCTGTTCTCCTCTACATATCTCCCCACCGCATCTCTTTCAGCAGTTGTTTCTAAAAATATCCTCCTAGTTTCATTTTTGCAGAAGTGTTTTAGGCTAATATAGTGGAATGTATCTTAGAGTTTAACTTATTTGTTTCTGTCACTTTATACTAAGAAAACTTATCTAAAAGCAGATGTTTTAACAAGTTGACTCAATATAAAGTTCTTCTTTGCCTCTAGAGATTTTTGTCTCCAAGGGAATTTTGAGAGGTTGGAATGGACAAATCTATTGCTGCAGTTTAAACTTG 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000408 2623 GATA1 NCBI REGULATORY POLYMORPHISM 11-Oct-2005 0 reference_sequence tttttcattctcacaaactaatgaaaccctgctTatcttaaaccaacctgctcactggagcagggaggac 0 false GERMLINE 0 variant_sequence tttttcattctcacaaactaatgaaaccctgctCatcttaaaccaacctgctcactggagcagggaggac 0 false rSNP_BIB Cross-reference: http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-id+2eRHV1R75Ax+-e+[rSNP_BIB:'RFrSNP0M0010'] 11-Oct-2005 smontgom 11-Oct-2005 40bp 5' sequence + 36bp of first exon were transfected and showed increased (15-20 fold) activity with estrogen treatment. This demonstrated the presence of an ERE (Estrogen-Responsive Element). 11-Oct-2005 OREGEC00002 OREGES00019 OREGET00002 smontgom Used WT oligo, protein complex bound. Was supershifted with anti-ER. 11-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom Cell line: HepG2. Cotransfection of alleles. C allele has reduced activity compared to A allele (~16-fold reduction). Under Beta-estradiol treatment 11-Oct-2005 OREGEC00001 OREGES00019 OREGET00002 smontgom Looked at basal transcription. C allele has 2 to 3-fold increase over A allele. Suggested role of MLTF binding. 11-Oct-2005 OREGEC00001 OREGES00019 OREGET00002 smontgom Cell line: HepG2. C allele bound stronger complex. This was competed out with MLTF oligos. 11-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom MLTF antibody supershifted competed by C allele. No supershift with non-specific antibody NF-1. 11-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom Cotransfection with MLTF expression vector. C had 3- to 4-fold increase compared to A allele. 11-Oct-2005 OREGEC00002 OREGES00019 OREGET00002 smontgom 183 AGT NCBI 399 POSITIVE OUTCOME 9931090 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000409 ERE / MLTF ERE / MLTF USER DEFINED REGULATORY POLYMORPHISM 11-Oct-2005 0 reference_sequence ccccacccctcagctataaatagggcAtcgtgacccggccgggggaagaagctgccgttgttctgggtac 0 false rs5050 dbSNP GERMLINE 0 variant_sequence ccccacccctcagctataaatagggcCtcgtgacccggccgggggaagaagctgccgttgttctgggtac 0 false Mutation observed in 3 black individuals possessing the Fy(a-b-) phenotype. Not found in 100 randomly-selected Duffy + Japanese. rSNP_BIB Cross-reference: http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-id+2eRHV1R75Ax+-e+[rSNP_BIB:'RFrSNP0J0014'] 11-Oct-2005 smontgom 11-Oct-2005 Cell line: HEL and HMvEC cells. HEL cells showed disrupted promoter activity for C allele vs T allele. 11-Oct-2005 OREGEC00001 OREGES00019 OREGET00002 smontgom Supershifted by anti-GATA-1 in HEL cell. The probe is annotated as the search space sequence. 11-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom 2532 FY NCBI 400 POSITIVE OUTCOME 8651934 0 search_space CCCTCATTAGTCCTTGGCTCTTATCTTGGAAGCACAGGCGCTGACAGCCGTCCCAGCCCTTCTGTCTGCGGGC 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000410 2623 GATA1 NCBI REGULATORY POLYMORPHISM 11-Oct-2005 0 reference_sequence gcgtggggtaaggcttcctgatgccccctgtccctgcccagaacctgatggccctcattagtccttggctcttaTcttggaagcacaggcgctgacagccgtcccagcccttctgtctgc 0 false rs2814778 dbSNP GERMLINE 0 variant_sequence gcgtggggtaaggcttcctgatgccccctgtccctgcccagaacctgatggccctcattagtccttggctcttaCcttggaagcacaggcgctgacagccgtcccagcccttctgtctgc 0 false rSNP_BIB Cross-reference: http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-id+2eRHV1R75Ax+-e+[rSNP_BIB:'RFrSNP0J0015'] 11-Oct-2005 smontgom 11-Oct-2005 Cell line: HeLa and K562 cells. G allele enhanced the intensity of binding. 11-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom anti-SP1 supershifted protein-DNA binding complex in mutant allele not WT allele (C allele) 11-Oct-2005 OREGEC00002 OREGES00002 OREGET00001 smontgom 3048 HBG2 NCBI 401 POSITIVE OUTCOME 1688466 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0000411 6667 SP1 NCBI REGULATORY POLYMORPHISM 11-Oct-2005 0 reference_sequence cagcagtatcctcttgggggcCccttccccacactatctcaatgcaaatatctgtctgaa 0 false GERMLINE 0 variant_sequence cagcagtatcctcttgggggcGccttccccacactatctcaatgcaaatatctgtctgaa 0 false This polymorphism was chosen because of disconcordant frequencies in african and european populations at this position. 31-Oct-2005 smontgom 31-Oct-2005 Cell line: HepG2 (used nuclear extract). Bound strongly to G allele compared to T allele probe. T probe labelled as search space sequence. 31-Oct-2005 OREGEC00001 OREGES00001 OREGET00001 smontgom Each probe was competed with an unlabelled competitor (the probe with the alternative allele). Differential binding patterns were observed. 31-Oct-2005 OREGEC00001 OREGES00003 OREGET00001 smontgom 80781 COL18A1 NCBI 1997 POSITIVE OUTCOME 16229994 1-Nov-2005 1 obig 0 search_space AGACTGAGGCCGGGAAGGAGTATGCATTCCTGCCCTGGTCC 0 false 0 sequence_with_flank EMPTY 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0001732 UNKNOWN UNKNOWN USER DEFINED REGULATORY POLYMORPHISM 31-Oct-2005 0 reference_sequence accggatccttttgtggacggggagactgaggccgggaaggagTatgcattcctgccctggtcccgggctccgtctctgc 0 false rs755548 dbSNP GERMLINE 0 variant_sequence accggatccttttgtggacggggagactgaggccgggaaggagGatgcattcctgccctggtcccgggctccgtctctgc 0 false Promoter description: testis derived transcript (3 LIM domains). This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.416502947 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 5.178597039 HeLa: 5.717058082 HT1080: 4.884851538 MRC5: 3.291587284 JEG3: 5.993174926 U87: 4.504337514 G402: 3.818663379 HCT116: 5.774321884 CRL1690: 3.927734702 AGS: 5.642756966 Panc1: 4.064194284 HMCB: 4.253541987 MG63: 3.406070104 Snu-182: 3.747317265. Number of positive cell lines: 14. Mean: 28.17177311. Mean(log): 4.586014783. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 26136 TES NCBI 1998 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CCTGAGAATTTTAGTCGCAAGGAATGAAAAAAACTGTTTTCTCATTTCGAGTTTTTATTGGTCAATAGCTTCCTAACCGAAAACTCTGCAGTCCTAACACAATATTTTGTATCCATTTTCAAAAATCCAGTTCTGGGCATAAAATAGAATTAATGCTCAAGTCAAAAACTTTGTGTTTAGAAGATAAAATATTAGGAACCATGAGTATGAGAAAAACAAAAACTGTTTTCTGTATTTTTCCCTTCCTCTCTCTGCAAAACTTCTCTATTTGATAAGGGACAGCTAGCTTAAATTTACCACAAAGTAAAACATGAGCAAATCCCCTGGAACGAGGAGAACTTTCGCACAGGGCAATTCACTCGAATGTGACATCAGCATTCCTTCTGAGTCATAGTCTGGTCCCCACCCTTTTCTCCCAGGCGACACCAGGCTCCGCATAACCCGGGAGTGGCTCAGGTAGGGCCGTCGGTTCCAGTGCCTGCGAGGCAGCAGCCAAGCTGAAAATGTCT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003433 REGULATORY REGION Promoter description: "capping protein (actin filament) muscle Z-line, alpha 2". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.559414991 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 6.108844296 HeLa: 4.138436445 HT1080: 4.871262384 MRC5: 3.910455679 JEG3: 4.215337692 U87: 3.788578991 G402: 4.576638579 HCT116: 3.353065931 CRL1690: 3.282791422 AGS: 4.885228028 Panc1: 4.67900208 HMCB: 6.130147374 MG63: 5.663409796 Snu-182: 2.068010165. Number of positive cell lines: 14. Mean: 26.65898572. Mean(log): 4.405086347. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 830 CAPZA2 NCBI 1999 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence tttttccccctcaacactgtatccccagagactaacacagtgccccgcaccccgttaaagaaccaaaaaatatttgttggatgaataaaGGAGTATATCAAGAGCAATCTTTCAATTATGGAGAGGGTCGTGATGTGTATTTTAATGAAAGCCAACTATCTTCTCTAATATTTGAAAAAACAATGTTTAAAAGGCTTCTATTTGTACACCTTTTCACATTTTAGCTGGCAGAGTTCAGGACTTGATGGAAACATAACGAAGGGCTCAGAATGTACTCATCGCAGACTGAGCCCATATGGTCACAGTGGGGAGAGCACGCTGCACTCAAGATGCTAGCAAGCCTGCAGCAGGCGGCCCAGCGAGACACGGTCCCCCGCCCGGCCACCAGGCGCCCGCGCACGCGCACAGCCGCGCTCAGTCCGCGAGGGCCGGGTCGAGGGAGGCGGGGCTCCCGGGGTGCGCGTGCGCGGCGGCCTGAGCGGCGGGCCCCTCCCTTAGCGGGGGCGCGCGGCGCTGAGGACCGCACGGAAACGGGGAAGTCAGGTGg 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003434 REGULATORY REGION Promoter description: suppression of tumorigenicity 7. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.5 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.76804931 HeLa: 0.946824394 HT1080: 0.598276956 MRC5: 1.064335366 JEG3: 1.635222791 U87: 0.992085746 G402: 0.997255864 HCT116: 0.866408763 CRL1690: 0.756619734 AGS: 1.053205147 Panc1: 1.05909984 HMCB: 1.423150656 MG63: 0.818300657 Snu-182: 1.14509123. Number of positive cell lines: 0. Mean: 1.046811708. Mean(log): 1.00885189. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 7982 ST7 NCBI 2000 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TAAATAGCATCTGCCACCCAAATCTTGCTGAATAGAGTGATTTATCTTCAGGCCTACTAGCCGGCGACAGGAGCGCACCTCCTCCCTTCTCCTAGCTGTCCCGGGTTTATTCATTCCCTGAGCCTGAATCCTGATAAGGGagcagagtagggtttaagacctcggaccccagaatacaccactgcaattgaattttggttccaccttaaggtaaactacgcagctgctgtgagcctcagtttccctacctatagaaagaggatcgtagtggggaattgttgcaggggttaaatgagattgtacggatcgtggagcagcgcctggcgtgtggtaaacgctcaacttatgcgggttgtAACTGCCTGAGGCGTTTCCTTCGGCGCGCCACTTGGCCTTCTCTTTCTAAATATTAGCATAATAAATATAAATGGACCCAGAACGCGAGGGGGCAGGGGCCACGTGATCGCTCCACGAAAGCCACTTGTAGGGACCTTTAGAGAGTTAGCAATAAGGCTGGAGAAGGA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003435 REGULATORY REGION Promoter description: suppression of tumorigenicity 7. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.453703704 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.17552254 HeLa: 0.828561058 HT1080: 0.360968085 MRC5: 0.912438127 JEG3: 0.427796261 U87: 0.824405198 G402: 0.829148051 HCT116: 0.625789124 CRL1690: 1.085900526 AGS: 0.512290659 Panc1: 0.300935294 HMCB: 0.518373209 MG63: 0.491523976 Snu-182: 0.986931909. Number of positive cell lines: 0. Mean: 0.579190015. Mean(log): 0.63432743. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK055405 AK055405 USER DEFINED 2001 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence aattctcccaaggatggaacattctagataggagggatagaagcaaatcattctatacgttggaagcattggggcttcgtattcttgtggaaccttgttgagaagggcAGGTGTCATCCAGGAAAGAAGGGACCACAGTACTTTGCTGTGCAGCATGGGGAAAAGGGAGCATTTATGGACATCAACCAGGATGAAGCTTTCCTCCTGATTTTCAGAGGCTTCACTTTTGTGCTTTTTATCCAAGTCAGGTTAGTGCCCAAAACAAAGCAAACAAATAAAGGCCTTTATTTTAAGCCAACCTTGTAACATCTCCATTCATTCTACAGCTCAAGGTGAGGCTCCCCGAGGACCCCACATTTTAGTGTGTGTGCATCACCCAGAGTACAGACTTTGAGCGATGCCTGTTATCTAGCTGCGCTGGCTCATGTTCAGCAGTTGCAACAGCTCCATGGCTGCAATGGCTCAATATCAGCAGTTCCTTCCCCACTCAACCACAACTTCAACAGTTCTAAATCTGTTTTTGGCCAAGTCTTCAGGATA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003436 REGULATORY REGION Promoter description: "Clone IMAGE:782833 ST7OT2 mRNA, non-coding transcript". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.411067194 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.084644735 HeLa: 0.718500467 HT1080: 0.403341314 MRC5: 1.133014951 JEG3: 0.285999295 U87: 0.47877901 G402: 0.504361568 HCT116: 0.556187488 CRL1690: 0.902010749 AGS: 0.252689773 Panc1: 0.539494748 HMCB: 0.835926311 MG63: 0.920990726 Snu-182: 0.875909281. Number of positive cell lines: 0. Mean: 0.553604539. Mean(log): 0.606560744. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 93654 ST7OT2 NCBI 2002 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence GGATCTAATCAAATCCCCCAAAATGTCCCAACAAAGTATACATTTGTCATAGTCCACAAAAAGATCAAGAAGTCACTACTTAAGATAACAATGaataggtgctctctcaaatgtaacatgttcaaaactgaactcgtaattttctctcaaaaaacctctctcaccccagacttccacatcttagctgacacaaactccttccctttcaaggcaaatatttagaatcagccctgacttctcttttttcttgtactgcatatctgattaattagcaaattctgctagtcctgccttcaaaatatatctagaatctgatcacttcacaccaccttctctgctaccactctggcctgagctgccattgtggcttgccaagattaatacaagagcctgctgaccgactcctccgcttctctgctgctacacagcagcctgtaaaaattaagactggtcatgtcactcctctgttcaaaaccttgcaaagctctccatttcacccagagtaa 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003437 REGULATORY REGION Promoter description: wingless-type MMTV integration site family member 2. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.596566524 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.176452742 HeLa: 1.005570503 HT1080: 0.653508115 MRC5: 0.358071304 JEG3: 0.426802524 U87: 1.12838215 G402: 0.476369998 HCT116: 1.030105525 CRL1690: 0.842762899 AGS: 0.501143636 Panc1: 0.653273332 HMCB: 0.698301658 MG63: 0.447780843 Snu-182: 0.715456043. Number of positive cell lines: 0. Mean: 0.597601582. Mean(log): 0.650998662. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 7472 WNT2 NCBI 2003 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence GCAGCTCCAAATTTACAAGTGCTAGCTCTTCATCCCAGCTTCAGGGAGAGAAGCGAAGCAATGAGTTGAGAATCATCTCTGGATTCTTGTATCCCATGCATAGTAATCTCCTTATCCCCTGGCCCCCTTCCTCGTTTCCTCACATTGCACGCTCAGGGACTTGTTTGCCAGCGGATGGCCTCGGCAATCCGGAACGCACGCTCCGAGAGCCCACGGATGCTCTTTGGCCTGGAGCTTCCCTAAAGGTTCCTGTATTCGCGTGTGCTCGTAACCATGCAGCGATGTTCCCCCTTCCCCGCCTCACCTCATCCCCAGACATCTCTTGCCATCATTTCATGCACCCGTGTCTAAAACCCCGCGTTTCTCCCCACCCCCGCCAGGCGCAGCACCCCCTCCCTCGGCTGCGCCCGGAGGGGAGCAGAGCGGACGGGGCGCGCGGGAGGCGCGCAGAGCTTTCGGGCTGCAG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003438 REGULATORY REGION Promoter description: GASZ. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.613686534 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 3.812587023 HeLa: 2.956919142 HT1080: 2.960026902 MRC5: 1.505322929 JEG3: 3.886560891 U87: 3.544352397 G402: 2.376899823 HCT116: 1.831696783 CRL1690: 4.847127819 AGS: 2.881226735 Panc1: 1.827876847 HMCB: 3.735752565 MG63: 3.308321587 Snu-182: 2.527363487. Number of positive cell lines: 11. Mean: 8.738610408. Mean(log): 3.000145352. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 136991 ASZ1 NCBI 2004 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TTGCCGTTAAATCCTAGTGTGCTCCTGCCACAAGTAAGGCATTCCTTGCAGAGCAAGAATTTCATCATTTCATCAAGCAAATACTTTAAAGAGGTCGAAAGGTAAGTCCCTGAGAGGAACTGGAAGTGCCAGCAGAAGCCTGGCGCACGAACTTCGTCACCAGTGTCAGACACGCCAGGTTTTCACCTCAAGAAGCCTCAAGGTTAGGGAGGGACGGGGCAGGGAGGAGAGCAGCGCGCCGCTGTGCGCCTGCGCTGGAGGGCTCCAGACTGGAGCGCTTCCACGGCGCTCCTTCCCGCGCATCTCTACGTACGCCCCACCCCGGTGCGCATGCGCCCGGAGAGCTGAAGGGCGCGCGGTGCCGACAGGGAGCTTCCTTGGCTGGCATGGCGGCGAGCGCGCTGCGAGGCCTGCCAGTGGCTGGCGGAGGCGAGAGTAGCGAGAGCGAGGATG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003439 REGULATORY REGION Promoter description: testis derived transcript (3 LIM domains). This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.408536585 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.36228178 HeLa: 1.00078111 HT1080: 0.821637382 MRC5: 1.149873629 JEG3: 0.841161064 U87: 2.106949969 G402: 0.855003593 HCT116: 1.142790133 CRL1690: 2.326104189 AGS: 0.719609008 Panc1: 1.007020504 HMCB: 0.712255869 MG63: 0.809303814 Snu-182: 1.038084222. Number of positive cell lines: 2. Mean: 1.25030269. Mean(log): 1.063775448. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 26136 TES NCBI 2005 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence AATCTACTCATCCCCTCACCCATGTATTATGATGGGTTACCCCTGAAGAAATAATACCATAGCCTTTAGGCATCGCAAGAATGATCGCAGTATTCAAGTTTGGGGATAAAGAGCCTTAATTAAGACCTCTCAAAGCAGCTCTCTGTGGGATCCACCCTTTAGAAGCAGCTGTGGAGATAGTGACACAAGACCAAATTAGGAATGGTTGCCATGATCCAGATTCTTTTATGGAACTCCTACAGATGCGTTTTGGAATCAGGTTTTTAAAGTCCCTTTTATAGCAAATAAATAGGAGGTTTTGAGGGCTGTTTATGAGCGCATTCCATTACAGTGTCTTTCAGCGGAGCCAGAGCTCAGCCAATCCTAATTAAGAAGCAATTTCAGCTGCAGTCATTGCTTATTATAATAATTGTGACATTTTTATAGCCCTACATTGTCTTTCTCAAAGTAACGGATTCAGGAGGAGTCCTTTTCTGAGTAGAGTCCACAGAA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003440 REGULATORY REGION Promoter description: testis derived transcript (3 LIM domains). This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.617760618 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 5.394805881 HeLa: 3.363369664 HT1080: 3.195598323 MRC5: 1.669832587 JEG3: 4.458263232 U87: 1.649508639 G402: 3.417623014 HCT116: 3.509062471 CRL1690: 2.081854237 AGS: 5.060350231 Panc1: 3.74699469 HMCB: 2.218391601 MG63: 4.673849557 Snu-182: 1.876233017. Number of positive cell lines: 11. Mean: 13.05532074. Mean(log): 3.308266939. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 26136 TES NCBI 2006 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence AGGAATCCCTAACGATCCCTACAATCTCTCTCTCTCTCTTTTTTTTCTCTCTTTACCCTGAAAATAAACTGAGAAGTTAGTATTGGGATAACTATTCCCCTTGACCCAAATAAAAAGTCCTGGGCAAACACAGGTACAAATTGCCAAATGGAAAAAGTTCTTCTCCATCTTCAGCTAGAGGGAGGCTGGGGATCCCAGCTCTTTAGAAGCCGGCCCGTGGACGCCCAGAGAATCCCTTCGGAGACCAGGTCAGGGTCACTGAGCTTGCCCAGCAGGGCGCCGCCTCGGACGCCGCCCCGCCTCTCACCTTGCCAGCGCCGCGCTCGGGCCGCGAAGGTGCGTGCGGCGCTCGGTGATTGGCGGCGGCCCGGAGCTGCCCGGCTGCCATTGGCTGCCCGGCCCCCTTTGTTCCCGGGTCCGGGCCGCAGGCCCGCTGCGGCGGACTGGGCGGCGGAAGTTCGACGGCGCCGGGCGAGTGGCTGTTGAGCGGCGCCGCGGGAGTTCCGCAGGTTTCCCGT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003441 REGULATORY REGION Promoter description: cortactin binding protein 2. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.351145038 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.788537824 HeLa: 0.963095526 HT1080: 0.491360752 MRC5: 1.059020403 JEG3: 1.184157265 U87: 0.720678186 G402: 1.000980861 HCT116: 0.718020558 CRL1690: 1.007105922 AGS: 0.615915883 Panc1: 0.632983238 HMCB: 0.69616979 MG63: 0.664024637 Snu-182: 0.648932627. Number of positive cell lines: 0. Mean: 0.757037178. Mean(log): 0.799355962. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 83992 CTTNBP2 NCBI 2007 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence tgtgggtgctgacactcagtaattttttattcttctttATATATACCAAAATTTCCATAATGAAATGCATTACTGTTTTAACCACGAACAAGCTAAATAAGCATTGACAAAATTCCACATAAAGAGCATCTGCAAAGGATAATATAGAAAAAGTTACAGAATTTCTGGAAGGGACAAAATGAACTTGGAACTGTGTGTCTCAGCTACCCTGCAGACCCTCGCTATGGAAAATAGAGGGAAAAAATGTGTTTTTTTATAAAGTATCAGCTCTTGCTAAGTACCCTTTGCCCATGTTTCACATTCAAATGAGAGTACAGGTGTCCAATGATAAAGCTAATCTCTAAAATATTGTTTTTAATCTTTTGAAAGTATGAGGACAATCAAAAAAGAATTCCACACCTGTGTACCACTTTTTTCTCTCATCAATTTAGCATCTTCACCCTAGCTCTCTACTTGGTTTGTTAATAGGTTGAGCAATATCATAATGTCATTTTCCACGGCCCAGAAGGAAGCTTGCAAGACTA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003442 REGULATORY REGION This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.38021978 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.563326462 HeLa: 1.321707045 HT1080: 0.652596387 MRC5: 1.205772084 JEG3: 0.903248308 U87: 1.130217286 G402: 0.713627071 HCT116: 1.172210121 CRL1690: 2.496230518 AGS: 1.101603316 Panc1: 0.792379045 HMCB: 1.405392542 MG63: 1.275577992 Snu-182: 1.095959706. Number of positive cell lines: 1. Mean: 1.323994944. Mean(log): 1.13070342. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK097428 AK097428 USER DEFINED 2008 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ccctctagagaaccctggctaaACActtatttcatttttgtctataacacttatacaacctggcttatataaatctgttttgttattcattcattgttgtcacgtcaacaatagtaatattcatagttcaggcacattgtgtattttgttcactgctgtaaaactaaaatgatacttggcacagagttgacactcagaaatatgtgttgaataagtaaatTCTGGTGTGGCATAGAGTTCTGGCTGTGGTCCCATCCTGCAGAAGCAAAATTCTTTTAGTATTGTGAGGTCACAGAGTCATGGCATTCTCACTCGCATCTTCCATGGGGAGACAGGTGGAATGGTGAGGTACCCTTGGAAGGTTAAGAGAAAAATTTAGTAAACACTTTTGAGTATATAGACTCTTGCTGCATGATCCCACTGTGTAAGAATTTGCTTATTTCCAGGGCTTCATA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003443 REGULATORY REGION Promoter description: caveolin 2. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.509090909 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.412411551 HeLa: 0.558865959 HT1080: 0.40680367 MRC5: 0.781259636 JEG3: 0.577182937 U87: 0.688469893 G402: 0.549719551 HCT116: 0.860112502 CRL1690: 0.509803094 AGS: 0.91770813 Panc1: 0.649428017 HMCB: 0.573912567 MG63: 0.404770966 Snu-182: 0.782493741. Number of positive cell lines: 0. Mean: 0.546066596. Mean(log): 0.619495872. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 858 CAV2 NCBI 2009 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence aactctgccacacacacacaaacacacacacacacacacacacggtgtagtttaggaagtaaaaaaaaaaaaaaaaaaaaaaTCAGATCTCCCCTCACACCTCAGATCTGAAGGCACAAACTCTAGGGCCAGGGCGTTCGCCTACCCAACTCCACATGCACTTGCAGGTCACCTAGCACTCAGGTACCTAGCACTCAGGTACATTGTGGCTCCTTACCTCTCACGACAGCAGCAACAACGTTGATTGGAAGTTTATCACTGTGTGTTACGGGccatgggccatgtgtgttagaattttatgtgaaattaacatttaattctcacggacacccctgaaacagatgccacagcccccattttgccaacgaggcagctgaggttcccagaggctcaataccagcaccatgagccgcagcacgcaaggcaaacacagccggaggtgagcacatacctgcttcgcaccccatgcGCCTAACCACAAGGTTCCCTCCCTCCAGGAAGGCCGTTGTCTTCCCTGGGACGACTTGCCAGCTCTGAGGCATGACAGTAC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003444 REGULATORY REGION Promoter description: "caveolin 1, caveolae protein, 22kDa". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.539784946 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 1.433380028 HeLa: 2.954213628 HT1080: 3.953471804 MRC5: 2.399875539 JEG3: 1.708151981 U87: 5.122469863 G402: 4.18650762 HCT116: 3.175008529 CRL1690: 2.425563905 AGS: 3.095620199 Panc1: 2.156807563 HMCB: 1.668060727 MG63: 2.832016555 Snu-182: 0.928005036. Number of positive cell lines: 9. Mean: 8.081722361. Mean(log): 2.717082356. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 857 CAV1 NCBI 2010 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CTTAAGTTTCCATCCACACCGACTAGATGTAAACGAGTGTCACCAAAAGTACACCACAGGCACCCACACAGATTCCTTCCATAAGGGATCCACAAAGTTTAGATGTGAAATGTACCTAAAGGTTCCTAGCCGTCTTTCATCCCTCCCTCTGTGAAACAGGGAGACACATGTGTTTTAAGGCAGAGATGGAACTTGGGCGATGGGCGGGGGGTGGGGGAGGTGGGAAGGGACGGCTTAGGACAGGGCAGGATTGTGGATTGTTTCTGCCGCCTTGGTTGCCCATACTGGGCATCTCTGCAGGCGCGTCGGCTCCCTCCACCCCTGCTGAGATGATGCACTGCGAAAACATTCGCTCTCCCCGGGACGCCTCTCGGTGGTTCAGAGCAGGGAAAATGTTGCCTCAGGTTTAAAATAATCTGCCCAAGCACCCCAGCGCGGGAGAAACGTTCTCACTCGCTCTCTGCT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003445 REGULATORY REGION Promoter description: met proto-oncogene (hepatocyte growth factor receptor). This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.375 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 3.336965463 HeLa: 1.16273559 HT1080: 2.314718707 MRC5: 1.685257173 JEG3: 3.127069988 U87: 1.501889375 G402: 2.49405368 HCT116: 2.719299919 CRL1690: 0.596462109 AGS: 2.845981165 Panc1: 1.901040932 HMCB: 1.993643818 MG63: 1.092080871 Snu-182: 1.264083099. Number of positive cell lines: 6. Mean: 3.662516876. Mean(log): 2.002520135. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 4233 MET NCBI 2011 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TTGGGAGGCTTTCTTCTTCTTTTACAAGTAATGTAAAATTGTAGTGAAGCTATTGGAAAAGAAAAGGATAGAAACATGTTAGTGCTTTGACACAGCGGGAGAGAATTTTGGAAGAGATATTCTACCAACTACAGATGGAATCTTCATCATCATGTAGACTTCAGATATTCTTTTAGAAAACTTTACATTTACTTATAATCTAAACCTTACTTGTTTAAACAAGTCATGAAATGTATAGCTTAATAATTGCCTTTAAGAAAATTGTTGCCCAAAACAGAAACCGTATTGAGTATGTAAAGCCAAGTTTAGTTACCAAGACCTACTGATTTCCTTTCATATATGTATGGTCACATCTCTCACCTCATCTGTCCTGTTTCTTGTTTTACTAGTGGTCCTTTGGCGTGCTCCTCTGGGAGCTGATGACAAGAGGAGCCCCACCTTATCCTGACGTAAACACCTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGACTCCTACAACCCGAATACTGCCCAGACCCCTTGTAAGTAGTC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003446 REGULATORY REGION Promoter description: met proto-oncogene (hepatocyte growth factor receptor). This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.352422907 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.133449275 HeLa: 0.874347117 HT1080: 0.375004542 MRC5: 0.683709303 JEG3: 0.52666674 U87: 0.912792529 G402: 0.943548131 HCT116: Bad Txfn CRL1690: 0.745237091 AGS: Bad Txfn Panc1: 0.256343171 HMCB: 0.484529722 MG63: 0.342691919 Snu-182: 0.931024442. Number of positive cell lines: 0. Mean: 0.543692631. Mean(log): 0.600778665. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 4233 MET NCBI 2012 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence AAAAACCCACTGTTTGAGAATGATGCTACTCTGATCTAATGAATGTGAACATGTAGATGTTTTGTGTGTATTTTTTTAAATGAAAACTCAAAATAAGACAAGTAATTTGTTGATAAATATTTTTAAAGATAACTCAGCATGTTTGTAAAGCAGGATACATTTTACTAAAAGGTTCATTGGTTCCAATCACAGCTCATAGGTAGAGCAAAGAAAGGGTGGATGGATTGAAAAGATTAGCCTCTGTCTCGGTGGCAGGTTCCCACCTCGCAAGCAATTGGAAACAAAACTTTTGGGGAGTTTTATTTTGCATTAGGGTGTGTTTTATGTTAAGCAAAACATACTTTAGAAACAAATGAAAAAGGCAATTGAAAATCCCAGCTATTTCACCTAGATGGAATAGCCACCCTGAGCAGAACTTTGTGATGCTTCATTCTGTGGAATTTTGTGCTTGCTA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003447 REGULATORY REGION Promoter description: acyl-CoA synthetase long-chain family member 6. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.454365079 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.476725101 HeLa: 1.100931399 HT1080: 0.471687016 MRC5: 0.99507231 JEG3: 1.281773178 U87: 1.798893518 G402: 0.811240053 HCT116: 1.201988783 CRL1690: 0.562981649 AGS: 0.806520685 Panc1: 0.572094644 HMCB: 0.651177289 MG63: 0.625258678 Snu-182: 0.973998086. Number of positive cell lines: 0. Mean: 0.905201291. Mean(log): 0.880738742. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK122702 AK122702 USER DEFINED 2013 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TTGCAGAAGTGCTTTACCATTCAAGCTCTGTGCAGTACAGCTCCGTTTATGACCAAAACACTTATGTTCCATAACTTTTATAATTCACAAACTCCTAAAAGAGAAAACAAAAGAGTAAAGTTGGGGAATGAAACTGGCATGGCTCTTCAGGCTGCAGATGGGGACTGGCCTGAGGCTGGCCCTGAGACAGGCCTTGTGGAAGTACAGAGGGAGTGGGAGGAGGAATCCATATGTGATTATGGAGACAAGGAATTCTCCATATATGTGTCACTCAAGGGACCAGCATATGAAAAAACTGTGTCTTCTAGGCCTTTCCCATTTTGCCTTGGGGGAGGTCTTATGTAATAGTgcaggtaaggccgtggcatctggagagcatgctttccagctttccagacctggattcaatgccagcaattactgtaaattagttttgtgaccctgggcaagtcatgtaacctctctgagctttgtgttccttacctgtagaaatgccacttccct 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003448 REGULATORY REGION Promoter description: acyl-CoA synthetase long-chain family member 6. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.597042514 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.334269119 HeLa: 0.90724889 HT1080: 0.328175165 MRC5: 0.995055505 JEG3: 0.375245461 U87: 0.718533933 G402: 0.716504834 HCT116: 0.780587711 CRL1690: 0.822505433 AGS: 0.600955565 Panc1: 1.243402107 HMCB: 0.799319171 MG63: 0.661561477 Snu-182: 0.940678262. Number of positive cell lines: 0. Mean: 0.684474495. Mean(log): 0.73028876. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 23305 ACSL6 NCBI 2014 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TGCCACATACAGTTGTGTACGAAGATCATGATTTCCTCATGAGACACCTGTGATTCCATGTGGCTGCCTGTGACCATGTTACTACTGGTGAACACATATGGCAGCCTGTGATCACACTGAGTCTCCTGTGACCTTGCGTAGCCTCAGACCTGAACTCGTGCGTCCCCAGATGATCTGGGCACTATCTGGTCTAGCTGCCTGATTTGTCAGAGCCTAGGTGAACACTTGCCACTCCCTCCCCTCACTGGTTTGCAGAGGTGGCACCCGGAGGCTCCCCATGTCTGCAAACTCGGGTCCTAGGGGGCGTTGGTGTCAGCGGGCAACAGCCCACAGGAGTGTGCACCTCCTAGGACAGGTAACCGCGACCCGGCTGCCATTCGAGCCTGCCCAGCCATAAAACCCAGGCTGCGAGTCGCGCGGGGGCAGGGTCGCGTGTTGATGGGGTGGGTGGCGGCGGGGTGGGCTCAATGTCACGCTCTGGCGCTCGTCGCCCGTGCTCCCCCTTCCAGCCGGTTTCCGCAGAATGCCAGGTACTGACGTT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003449 REGULATORY REGION Promoter description: "solute carrier family 22 (organic cation transporter), member 4". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.712273642 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 5.085358285 HeLa: 3.891436073 HT1080: 4.426644737 MRC5: 3.082627743 JEG3: 4.23881512 U87: 3.57631529 G402: 4.61657637 HCT116: 3.765953624 CRL1690: 3.05130134 AGS: 3.925342202 Panc1: 4.264035517 HMCB: 3.411019716 MG63: 4.03187061 Snu-182: 1.658403766. Number of positive cell lines: 14. Mean: 14.75423024. Mean(log): 3.787550028. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 6583 SLC22A4 NCBI 2015 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CCTAAGCTCAGCCTCCAGATTGGAGGAGACCGCGGAGGGAACCCTGCTGGGGTCTGGGCCCGGGGCCACGCGGCCCGAGCAGATCGAGGGCCGACCCCTCCGAGAACTCGCTCTCTGGCCTCGGCTCCTCCCTTGCGCCCGCCCTCCCACGTGGGGCCCAGGTCTGGGAATCAGCGCTCGGGGGTGGCTGGGGACAACCGAGAACGAGCTTCTTCCCCGGCACGCGGGCGGAATGGCTGAGCCCAGCCTGGAAGCCCCCGTCAGGTCCTTGGGGGCGGGCGGGCGCGCGAAGCACAGGGCGGAGACAGCCGGGAGCCCAGCCTCCCGGGCTGGGCCGCCCTCCCCTTCCCCGCGCCCGGCCGGGGATGGGGGTGTGGTCCCAAGTGTACAGTGGCATCAAGCTCAGCGCGAGCTCCCGGGAACGCTCCAACGCCTTCAGCCTGTTTCCCAGGAACGGTCCCCGGCTTCGCGCCCCAATTTCTAACAGCCTGCCTGTC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003450 REGULATORY REGION Promoter description: "solute carrier family 22 (organic cation transporter), member 4". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.709923664 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 4.100779431 HeLa: 2.760463277 HT1080: 3.019162523 MRC5: 1.719923633 JEG3: 0.733292849 U87: 1.417154396 G402: 3.09673145 HCT116: 3.323494991 CRL1690: 1.137979419 AGS: 3.42592602 Panc1: 3.345376846 HMCB: 2.341139135 MG63: 2.755365062 Snu-182: 1.112723599. Number of positive cell lines: 10. Mean: 5.809104376. Mean(log): 2.449250902. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC043424 BC043424 USER DEFINED 2016 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence GTGGACAGGTAGACGTCCTGACTGAACTCCCAGCCATCCAGACAGCTCTCCTGCTCCAGCTGCCCCAGGTCCACGTCGCGCCCCGGCTCCAGCCCAAGCGCCGAGAAGTTGGCGATGGTGGCGAGCCGGTAGCGGCGGCAGCTGTGGGGCACCTCGCGGCCGTCCCGCAGCCGCAGTGGGACAGTGTGGTTGCGCCAGGCGCTGCTCAGGTTCGCGGCGTCCGGCACCCGGCAGCGGTGCTCCGGGGTCGCTATCAGGAACACGGAGGACAGGCCGGTGAAGCCATTGGGGATGATGCTGGCGCTGAGCAGGAAGAAGATGAGGCGCTGGAAGGGCCCCCACTCGCCCAGGAAGGCGGTCACCTCGTCGTAGTCCCGCATGCCGCCCTCAGAGGCCCACAGAGCGCGGCCTGGGGTCGGGGAACGCGGCGGGCTTTGCGCGTGCGCGCGGGGCACCCGCCGCCGACCAGGCAAGCCAGGCAGCAGGCGACCCAAGACCGTCCGCGGAGGGTAGGCTCGCGAGCT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003451 REGULATORY REGION Promoter description: "CDNA FLJ44796 fis, clone BRACE3040504". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.45540797 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.093677049 HeLa: 0.562436438 HT1080: 0.587781431 MRC5: 1.190332393 JEG3: 0.451439033 U87: 0.978737257 G402: 0.362890967 HCT116: 0.549983997 CRL1690: Bad Txfn AGS: 0.362587009 Panc1: 0.599495778 HMCB: 0.658288035 MG63: 0.317591141 Snu-182: 1.045744896. Number of positive cell lines: 0. Mean: 0.546680954. Mean(log): 0.596998879. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK126749 AK126749 USER DEFINED 2017 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence tagccgactgacacctcatacaggcaggtgcccctctgggatgaagcttccagaggaaggatcactcagcaatatttgctgttctgcaatatttgctgttctgcagcctctgatggtgatacccaggcaaacaggtctggagtagacctccagcaaactccaacagacctgcagctgagggacctcactggtagaaggaaaactaacaaacagaaagaaatagcatcaacatcaacaaaaaggacatccacaccaaaaccccatctgtaagttaccaacatcaaagaccaaaggtagataaaaccacaaagatggggagaaaccagagcagaaaagctgaaaattctaaaaaccagagcacctcttctcctccaaaggatcacaactccttgccagcaatggaacaaagctgggtggagaatgactttgacgagctgacagaagtggacttcagaaggtcagtaataataaacttctcccagctaaaggaggatgttctaacccatcgcaaggaagctaaaaacctt 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003452 REGULATORY REGION Promoter description: "Clone IMAGE:4795753, mRNA". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.489035088 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 1.545778307 HeLa: 1.116764849 HT1080: 1.383328644 MRC5: 1.166219679 JEG3: 1.238583761 U87: 1.283338952 G402: 1.597090542 HCT116: 2.494478362 CRL1690: 1.582457991 AGS: 1.672156301 Panc1: 1.736915889 HMCB: 1.488745305 MG63: 1.189505418 Snu-182: 1.130850708. Number of positive cell lines: 1. Mean: 1.870527757. Mean(log): 1.473301051. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC033946 BC033946 USER DEFINED 2018 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence atgatcctggaagacaagagctgagcaggctctcagcattctccttgcttcccactgccatttctaaatcataactccttcaccttcacatacataaaagacctgctcaggtttgtgctgtgccctcctggttgctgttaccaacatctgcctggttggttatccacattctgtgagctctctgacacccagcccaaggtgctggtgacttttgtgctcaggaagatgagtagtgctacaccttagcctcgcagtacttgaccttcacctatacttcacactcttgctgctgaggacacaccctgggcctctcatcagtcacaacagctccatctcactctaggacctttgttttcctcccaactcttcagctctcacctgatatcatttcctttccctttcagtttataccttGTGATCCCTCCAGCCCATTCATACTCTTGCCACTACCCCAGT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003453 REGULATORY REGION Promoter description: "solute carrier family 22 (organic cation transporter), member 5". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.490384615 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.916832281 HeLa: 1.186406346 HT1080: 1.209145945 MRC5: 0.949371031 JEG3: 0.857427083 U87: 3.918546065 G402: 1.185613187 HCT116: 1.362097997 CRL1690: 1.020461186 AGS: 0.781099455 Panc1: 0.622798052 HMCB: 1.030710506 MG63: 1.047671956 Snu-182: 1.173103017. Number of positive cell lines: 1. Mean: 1.988397949. Mean(log): 1.232948865. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 6584 SLC22A5 NCBI 2019 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ACCACACAGCCAGGTACTCTCTCTGACCCAGAGGGCAGGGAGCCAGGCTTCGGGAGGAATACTTAGAGGCCTCCTTGGAATGTGGCCACCGACAGGAATATGTGGGGGTGCAGTGAGGAAGCTGTCAGCCTGGGCCTCTGTCTTCCTGTACCCTTGAGGGACTGGTCACTTACTTTTCCTCATTTTCATTCACTCTGATTTGTTACTGACAAGGCCTAGGGAAGTTTTCACAGCCTAAAACACAGTCAGTATACTTACTGTTCTTAGAAACGTAACACTCCCCGACGCTGAGATGCAGACAGCTAAGATGCCAGGGATTCAAGTATGTTATTGTGTGCTCTGAGTCTCTGACCACCTCTTCTTCCCATACACTTATGATGTTGTTCCTGCAGTTACAAGACCTAAGTTCCAAGAAGCAGCAGTCCCACAACATTCTGGATCTGCTTCGAACCTGGAATATCCGGATGGTCACCATCATGTCCATAATGCTGTGGTATGTAAAAGAGACCTGCCTGAGGCT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003454 REGULATORY REGION Promoter description: "solute carrier family 22 (organic cation transporter), member 5". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.666666667 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 4.616696842 HeLa: 2.971722939 HT1080: 2.923859155 MRC5: 1.272095364 JEG3: 2.59102608 U87: 1.9970741 G402: 2.680009262 HCT116: 4.077135007 CRL1690: 2.235304525 AGS: 4.751995761 Panc1: 3.489534461 HMCB: 2.897894789 MG63: 2.525386593 Snu-182: 1.269053009. Number of positive cell lines: 11. Mean: 8.585287845. Mean(log): 2.878484849. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 6584 SLC22A5 NCBI 2020 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence AAGTCATAGCTCCCAGCCTCTCTACTAGGGTAGTTAACAGTCCCAGGTTCAAAATAATCCCCGTCCCTCTTATAAGATTAGGCGGTGTCAAGAGCAACTATCTGTGAGACCCTGGGCCAGTGACTTTCTCCTTACCTCCGCCCCCAAGTAGGCCTTGCAAAAAGCTGGGAGGGGTGCGTTTTCAACACTGGAGCTTCGCGGCCGCTCTCCCACTCGCTCCCCGCCCGGCGCTAGAGGAGCGAGTTCGGACTCGGACCCCAAGGCCTCGAGTCCCGCTGCCTTCCTAAGCCGAGCCCGGGCTACCTCGGTCGTCCCCAGCAGGCTTGGCTGGCAGAGGCCGGGCCTCGCCAGGTCCCCAGGACAGGCCCCGCCCGGGCCTCAGGTGCACTcccggcccgccccgcgccctcgcgtcccgccccagctccgccttcgccggcgccgctctgccTGCCAGCGGGGCGCGCCTTGCGGCCCAGGCCCGCAACCTTCCCTGGTCGTGCGCCCTATGTAAGG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003455 REGULATORY REGION Promoter description: "CDNA FLJ46914 fis, clone SPLEN2027852". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.524680073 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 2.671444775 HeLa: 1.03359527 HT1080: 0.48841119 MRC5: 1.039241222 JEG3: 0.312245342 U87: 0.932750448 G402: 0.45830389 HCT116: 0.663869398 CRL1690: 0.337024061 AGS: 0.760400091 Panc1: 0.701009631 HMCB: 0.805161397 MG63: 0.281878799 Snu-182: 1.142601312. Number of positive cell lines: 0. Mean: 0.981306593. Mean(log): 0.830566916. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AF086145 AF086145 USER DEFINED 2021 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CTTCTCTGACCAGTGACAGCCCTCACAGGCAAAGCCTCACCCTCTAGGGCCTGTCCCTTCCTGTCTGCCAGTCCCCACAGGGTCTGCGGGGTACCCAATCTCGCCAACCAGACTGGAAGCTCCCCAGGGGCAAGCAGCTTATCTCTTCCATATTCTCACAGTGTTCAGCCAGGATTGGCACTTCAGAGCATCTCCTGCTGCTCAGCAGAGATGTAGTTAGCATCTCTCTATAGTAGCACTTTCTGAGTCCCTCCCCTGGGGGAACCAGGCTAGACTCTGGGGTCCAGAGGAGCAGGCAGGCTGAGAGGCAAAAAGGGCACAGAGGAATAACCAACCCTGCCCCTGCAGTAGAGCCCTGGGCAAAACAGGCCATGACCAACCAGCAGCCAAGGTCAAAGTCCCCAGAACAAGGGCCAGTGTGTGCATGACATGCAGCATGACCGCTTGTCTCTTTTCGGCAGTACTGGAGATAGAAGGCTGAGTCATTAACAACTTTCTTTTATTAAAAATGTACATAAGTAAAAGGAACATGGTTTAATTGTGCAAA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003456 REGULATORY REGION Promoter description: "CDNA FLJ46914 fis, clone SPLEN2027852". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.496062992 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.21416765 HeLa: 1.219107168 HT1080: Bad Txfn MRC5: 1.039194903 JEG3: 0.353031077 U87: 0.655252643 G402: 0.689065749 HCT116: 0.708263328 CRL1690: Bad Txfn AGS: 0.81259141 Panc1: 0.700270117 HMCB: 0.649725402 MG63: Bad Txfn Snu-182: 0.980136696. Number of positive cell lines: 0. Mean: 0.68764032. Mean(log): 0.729164195. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK025221 AK025221 USER DEFINED 2022 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ttagtagagtcggggtttcaccatgttggccaagctggtctcgaacttctgatctcaagtaatccaccctcctcatcctcctaaagtgctgggattacaggcatgagccaccgcgcctggccCCATTTGAtttttttaagagacagggtatcacttcatcgcccagactggagtacagtggtgtgaccatagctcactgcagcctcaaactcctgggctcaagtgatcctcccacctcagcctcctgagtagctgagactccaggtacacaccaccacacccagccaattttttttttaagacagggtcttgctatgttgcccaggctggtcttgaacttctggactctaatgatcctcctgccttggcctaccaaagtgctggaattataggcgtgagccactgcacctggccCCATTTGATTTCTAGACTAGCATTTTAGTGGTGCTTCAGGAGAGAAAGGAAACTAGGAGTGTAAATAACTGATGTGTTGAACTGGAAACCCTGT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003457 REGULATORY REGION Promoter description: "Clone IMAGE:5745162, mRNA". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.546845124 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 2.500168505 HeLa: 1.259613855 HT1080: 2.202079733 MRC5: 1.730617379 JEG3: 0.442160374 U87: 1.493189184 G402: 2.14912853 HCT116: 1.059215006 CRL1690: 1.213710329 AGS: 2.464468828 Panc1: 1.950377853 HMCB: 2.352520202 MG63: 1.804866073 Snu-182: 1.07097284. Number of positive cell lines: 3. Mean: 2.505027904. Mean(log): 1.692363478. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC044238 BC044238 USER DEFINED 2023 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CTTGGTTAAGGGCACATTTTCTGGCAAATTTGGTAAATAGCTGAATATTCTGGCATCCCCATAGTCTGACAAAATTCCTCTTCTGAATGCCTCAAGAAGAAACAAATCTGAATTTCCTCCAGTTTAGCAAAAGGCTGTGCTGGTCAACGGGAATCTGCCACCTCCTGAATCCCCCCTCTGGAGGTCAGGCGGCACAGCAGCTGCAGCCTTAAGCTGCTCTCCCTCCGGCAGCAAGCGGTCAAGTTCTGCTGTTGGCCTGTGAGAGCCTACAGTGTCCACAGAGTTAACATTAGACTGGAGCGGCCCAGCCCTCAGCGGGCAGGAGCACTGGGAACTCAGGCCTCCTTTTCAAGGCCAGGATGAATGGGAAATATGCAAATGGCCGCCTCCCAGGAGCGGCAGGGGAGGGCCTGCTGCTGGCAGGAGGGCATCACTCCACTTGGGTCTGTCACATGAAAGGGTTTGTATTCCTGCCGCTGGCCGGCTCCTGGCCAGGCTGGGGCTGTTCTCACCAGAAAACAAA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003458 REGULATORY REGION Promoter description: MRNA; cDNA DKFZp686D10250 (from clone DKFZp686D10250). This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.521317829 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.099091881 HeLa: 1.265239616 HT1080: 0.273808983 MRC5: 0.983465587 JEG3: 0.287283354 U87: 0.764576441 G402: 0.627740701 HCT116: 0.562031758 CRL1690: 0.196303225 AGS: 0.295672006 Panc1: 0.355230636 HMCB: 0.500000196 MG63: 0.58372746 Snu-182: 1.096368936. Number of positive cell lines: 0. Mean: 0.521797931. Mean(log): 0.563610056. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AL713721 AL713721 USER DEFINED 2024 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ATGAATCTTCTCTAGCCCCGAACAGCACAGTGAATGGATAGGGCAGCAGATGAGCTCTGCCCCACGCCGGCCCTGTTTCAGAACAGCACTCCAGAGTGCCGCACTGCTTGCTGAACCACAGCTGTTACTGCAGATTGAGGAGCCTCAGAGGGAACAGAAGATAAAGATCATTATGGAATTTAGGATTGCAGGACATTCTTTGACATTTCATAACAGCCAGGGGAGATCAACTGTGGTCAGGGGACAGGGGCAGGAAGAAACCATGGCCAAGGCCTGTCTGGCAGGACTTGAAGGGGCAGAGGGACCCTTGCAAATGACCCTGCCTGGAACCCACCCCCAGTTGGCCCCTGTATAGCACTGATCCAGCTGGGGCTTTTATCCCAGGATACCCTCTTCAGGGATGCCTGTATTTGTTGATTATCTGCCATATGCCTGGTCACTGCAGAATACAAGGAAGAAAATAGCCTTCAGCAGAAGCTGAGACAGGAGCCTAGAGGATGGACAGTAAGGAGTCGA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003459 REGULATORY REGION Promoter description: interferon regulatory factor 1. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.73271028 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 8.506092937 HeLa: 7.445610598 HT1080: 7.571415752 MRC5: 6.26430447 JEG3: 6.643954136 U87: 7.781392056 G402: 6.275061875 HCT116: 6.281352312 CRL1690: 6.170393215 AGS: 7.505453689 Panc1: 6.214931291 HMCB: 7.154058206 MG63: 8.476641995 Snu-182: 4.479567493. Number of positive cell lines: 14. Mean: 151.0835964. Mean(log): 6.912159288. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 3659 IRF1 NCBI 2025 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CACCTGCGTTCGGGAGATATACCCCCGCCCCCGCCCCGCCAGGAGGGTGAAAAGATGGCCCCAGGAGCCAGCCGGCTGGGACAAGGCGGAGTGAGAGGACAGGCTGGGGCCAGGGGCGCTGGGCTGTCCCGGGCAGCCCTCCTCCGGGCAAGCCGGAGCAGGGGTGGATTGGGAGCGCTcggggcgggcccgcggtggccccggggcggtggcgcccggccggAGAGGGTGGGGCGGAGCAGCCGCCCTGTACTTCCCCTTCGCCGCTAGCTCTACAACAGCCTGATTTCCCCGAAATGACGGCACGCAGCCGGCCAATgggcgcccgcgcggctgtccgggggcggggccggccAGGGCTGGGGAATCCCGCTAAGTGTTTGGATTGCTCGGTGGCGCCGCTGCCCTGGCAGAGCTCGCCACTCCTTAGTCGAGGCAAGACGTGCGCCCGAGCCCCGCCGAACCGAGGCCACCCGGAGCCGTGCCCAGTCCACGCCGGCCGTGCCCGGCGGCCTTAAGAACCCGGCAACCTCTG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003460 REGULATORY REGION This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.410351201 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 26-Apr-2007 OREG0003045 bcb Cell lines tested and results, HepG2: 0.25330029 HeLa: 0.453702419 HT1080: Bad Txfn MRC5: 1.115239321 JEG3: 0.490537929 U87: 0.63539898 G402: 0.549378103 HCT116: 1.02280565 CRL1690: Bad Txfn AGS: 0.299301197 Panc1: 0.974953918 HMCB: 0.362046978 MG63: Bad Txfn Snu-182: 0.933127384. Number of positive cell lines: 0. Mean: 0.59747574. Mean(log): 0.644526561. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AL137501 AL137501 USER DEFINED 2026 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence tctcacaccagttagaatggcaatcattaaaaagtcaggaaacaacaggtgctggagaggatgtggagaaataggaacacttttacactgttggtgggactgtaaactagttcaaccattgtggaagtcagtgtggcgattcctcagggatctagaactagaaataccatttgacccagccatcccattactgggtatatacccaaatgactataaatcatgctgctataaagacacatgcacacgtatgtttattgcggcattattcacaatagcaaagacttggaaccaacccaaatgtccaacaacgatagactggattaagaaaatgtggcacatatacaccatggaatactatgcagccataaaaaatgatgagttcgtgtcctttgtagggacatggatgaaattggaaaccatcattctcagtaaactatcgcaagaacaaaaaaccaaacaccgcatattctcactcataggtgggaattgaacaatgagatcacatggacacaggaaggggaatatcacactctggggactg 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003461 REGULATORY REGION Promoter description: "interleukin 5 (colony-stimulating factor, eosinophil)". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.325 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.130438083 HeLa: 0.327974976 HT1080: 0.267082301 MRC5: 0.700272914 JEG3: 0.415398016 U87: 1.085691033 G402: 0.481150744 HCT116: 0.509043426 CRL1690: 0.141535029 AGS: 0.653353205 Panc1: Bad Txfn HMCB: 0.516585685 MG63: 2.648167591 Snu-182: 1.119106205. Number of positive cell lines: 1. Mean: 0.846182618. Mean(log): 0.691984554. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 3567 IL5 NCBI 2027 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TCCATTTCAATCACTGTCTTCCCACCAGTATTTTCAATTTCTTTTAAGACAGATTAATCTAGCCACAGTCATAGTAGAACATAGCCGATCTGAAAAAAACATTCCCAATATTTATGTATTTTAGCATAAAATTCTGTTTAGTGGTCTACCTTATACTTTGTTTTGCACACATCTTTTAAGAGGAAGTTAATTTTCTGATTTTAAGAAATGCAAATGTGGGGCAATGATGTATTAACCCAAAGATTCTTCGTAATAGAAAATGTTTTTAAAGGGGGGAAACAGGGatttttattattaaaagataaaagtaaatttattttttaaGATATAAGGCATTGGAAACATTTAGTTTCACGATATGCCATTATTAGGCATTCTCTATCTGATTGTTAGAAATTATTCATTTCCTCAAAGACAGACAATAAATTGACTGGGGACGCAGTCTTGTACTATGCACTTTCTTTGCCAAAGGCAAACGCAGAACGTTTCAGAGCCATGAGGATGCTTCTGCATTTGAGTT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003462 REGULATORY REGION Promoter description: RAD50 homolog (S. cerevisiae). This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.588235294 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 7.483265452 HeLa: 7.406738922 HT1080: 8.852894706 MRC5: 5.584960419 JEG3: 7.737469724 U87: 7.799116431 G402: 5.8946232 HCT116: 5.904754909 CRL1690: 8.799139147 AGS: 8.883665435 Panc1: 5.912970997 HMCB: 9.711390548 MG63: 6.968820709 Snu-182: 2.657289903. Number of positive cell lines: 14. Mean: 239.1769499. Mean(log): 7.114078607. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 10111 RAD50 NCBI 2028 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence atacacatgcgcacattccattaaccgccactgcaatggcgtcatcacatgttatgtgatcactggaaattactacacgaacgttagagagagaatgagaatgaaaaggaaaataGTTTTGACACGAACTGACCCCGCTTCCTGGGTCTCCAATCCACCCCACCACTACCCCCATTCCAGGAGTCCCAGGATCAAGCTTTGGGAAGCGCCATCCGTCACAGGTCTTGGTCTCCCCTTCCAAAAGTCAGTGCCTCTCCAGGCTGCCCATCCCCAGCAAAGATCCGGAAGTCCGCTGCCCCTGGCAACAGCACCCAGCACCTAGCCCTCTGCTTCGCCGTACCGCACCCGGAAGTCGGAGCTGCGCACGCACCGCGGGACTCTGATTTCCCGGCGTGCCCCAGGAGAGCGGCGTGGACGCGTGCGGGCCTAGAGGCCCACGTGATCCGCAGGGCGGCCGAGGCAGGAAGCTGTGAGTG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003463 REGULATORY REGION Promoter description: interleukin 13. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.511070111 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.166054354 HeLa: 0.350294018 HT1080: 0.485285865 MRC5: 0.911259755 JEG3: 0.366355564 U87: 0.860099721 G402: 0.494975099 HCT116: 0.611660108 CRL1690: 0.679594177 AGS: 0.96512365 Panc1: 0.433779056 HMCB: 0.823543712 MG63: 0.158280418 Snu-182: 0.771882068. Number of positive cell lines: 0. Mean: 0.515486593. Mean(log): 0.577013397. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 3596 IL13 NCBI 2029 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence AAATAAAACTCCCCAAATTCCCATAGCTGGTAGACTGTGGTCACAGCCACAGTGCACTAAGACTATCTGCTCAGCACTTCTGGTGACCCAAAAGGGTCTGAGGACAGGAGCTCAGAGTTGGGTCAGCTGTCCAGGTACTCAGGGTTGTCACAGGCAAAACTGCTGGAACTCAGGGCAGCATTGCAAATGCCACGCCGCTCTCAGGGCCCCTTGCCTGCCGCTGGAATTAAACCCACCCAGATCTTGGAAACTCTGCCCTGGACCCTTCTCAATAAGTCCATGAGAAATCAAACTCTTTCCTTTATGCGACACTGGATTTTCCACAAAGTAAAATCAAGATGAGTAAAGATGTGGTTTCTAGATAGTGCCTGAAAAAGCAGAGACCATGGTGTCAGGCGTCACCACTTGGGCCTATAAAAGCTGCCACAAGACGCCAAGGCCACAAGCCACCCAGCCTATGCATCCGCTCCTCAATCCTCTCCTGTTGGCACTGGGCCTCATGGCGCTTTTGTTGACCACGGTCATTGCTCTCACTTGCCTTG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003464 REGULATORY REGION Promoter description: interleukin 4. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.463917526 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 2.235271559 HeLa: 1.713377016 HT1080: 1.343827245 MRC5: 0.838348433 JEG3: 2.080716444 U87: 1.456616986 G402: 1.387862185 HCT116: 1.96147727 CRL1690: 0.998799496 AGS: 2.064184898 Panc1: 1.214438972 HMCB: 1.185330517 MG63: 1.380940395 Snu-182: 1.247902275. Number of positive cell lines: 0. Mean: 1.968190343. Mean(log): 1.507792406. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 3565 IL4 NCBI 2030 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ccctgatcacaacattgcatttcagcctgggtgacagagtgagaccctgtctcagaaaaaaaaaaaaaaaaGTCATTCCTGAAACCTCAGAATAGACCTACCTTGCCAAGGGCTTCCTTATGGGTAAGGACCTTATGGACCTGCTGGGACCCAAACTAGGCCTCACCTGATACGACCTGTCCTTCTCAAAACACCTAAACTTGGGAGAACATTGTCCCCCAGTGCTGGGGTAGGAGAGTCTGCCTGTTATTCTGCCTCTATGCAGAGAAGGAGCCCCAGATCAGCTTTTCCATGACAGGACAGTTTCCAAGATGCCACCTGTACTTGGAAGAAGCCAGGTTAAAATACTTTTCAAGTAAAACTTTCTTGATATTACTCTATCTTTCCCCAGGAGGACTGCATTACAACAAATTCGGACACCTGTGGCCTCTCCCTTCTATGCAAAGCAAAAAGCCAGCAGCAGCCCCAAGCTGATAAGATTAATC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003465 REGULATORY REGION Promoter description: "CDNA clone IMAGE:4831161, partial cds". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.365269461 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.103228134 HeLa: 0.695611598 HT1080: 0.557254058 MRC5: 1.059438567 JEG3: 0.397110144 U87: 1.108497416 G402: 0.484434659 HCT116: 0.503103703 CRL1690: 0.742452905 AGS: 0.597512185 Panc1: 0.446298573 HMCB: 0.621100591 MG63: 0.251158665 Snu-182: 1.140613773. Number of positive cell lines: 0. Mean: 0.572880489. Mean(log): 0.621986784. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC033341 BC033341 USER DEFINED 2031 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TGCTTTGCAAATGAAACAGCTTAAGACAGAGAAATTGAGATAATAATTAATAAATGTGTTTGGAAGGCTCCTCCAGCTCGCTTTAAGTTCAGGCTGTGGCTTCAGAACTGTGTTAACTCCTTCTGTAAAGGCACAGGCTAACGGTGGTCTTCAGTGATTTTTACTCTACCTTGTTTTAAAAATGGATTCAAAGTGATTTATTGGAAAAGATTAAGACAGAAAATAACATTATTAGGACCAAAGCAGAAAGGGAGTAGGAGGAAATGATGATCCAGAGAAAAATAAGACTATAAGCAGGTCATCAGATATTATAGTCCTATCAGCAAAAGCACAGTGGAAAACGCATTATTTTACTTCACTCTTTTTATATATGCGGGGAGAAAATAGTCTGATATAATAATCTGGTACTTAGCTTTAAAAGAAATTTCTCGAGAATCTTCACAAGATGATAGGATGGACAATGTCTTCAGCAGCATCCCGACAACACAGGCAGTAACAGAC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003466 REGULATORY REGION Promoter description: kinesin family member 3A. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.554865424 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 7.978088965 HeLa: 7.115487125 HT1080: 7.102486415 MRC5: 4.981572835 JEG3: 7.046804431 U87: 7.431472482 G402: 6.259547353 HCT116: 5.752684519 CRL1690: 5.985701353 AGS: 7.183442786 Panc1: 5.402865304 HMCB: 8.243756057 MG63: 4.732978907 Snu-182: 2.952957923. Number of positive cell lines: 14. Mean: 112.1209086. Mean(log): 6.297846175. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 11127 KIF3A NCBI 2032 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence gggctctggagatagatgtgagaatactaacaatctccttaagagagctcactttctaatggtaagacaGGTCATGAGGAAGTTAGCAATCAAGCGAGGTCAGGTAGGTAAGGTCTTCAATTCTTCGGATGAGACAAAATGTACAATTGCTATTACTGATTTTAATATTCCGGGTATTGCAAGGGCCAGAAGACGGGCCTAAGAGCAGCTCCTCCTCCCAACCCCGGGCTGCCAGGTTACCTCCGCCTCAGTGCGTGCCACATTTCTAGCGCAGCAGAATGGCAGCATTGCGCACGCGCGGCCTCAGTCTGGCGTCCTAGGAGATGGACTCGGAAAGCCTCCGCGCAGGCGTAATTCAAGGGCCGAGAGAGCCTGAGACTGGGCTTGGGGCGGGGCGAGCTCGGAATGCGGCTGCGCACTGGGCGCTCTCGCCCGAGAAGCCGCAGTCTCGAGAGCGTCAACGAGGTGTTTCGGTAGTCTCTG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003467 REGULATORY REGION Promoter description: septin 8. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.582969432 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.842872954 HeLa: 1.584571822 HT1080: 1.869533816 MRC5: 1.022442744 JEG3: 1.198371044 U87: 2.059651957 G402: 2.695157619 HCT116: 2.356452764 CRL1690: 1.365173737 AGS: 1.716987203 Panc1: 3.315027909 HMCB: 1.82057795 MG63: 2.596325797 Snu-182: 1.306385345. Number of positive cell lines: 5. Mean: 3.029145956. Mean(log): 1.839252333. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 540614 LOC540614 NCBI 2033 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TTTGGGGATCAGATCAATAAGGATGAGAGGCAAGAGGCGGGAAGGGCGGCCCCACCCAGCCTCCTCCCACCCCACCTACATTGGCCCCTATAACAGTAGCCCAGCCCTCACACTGCAGGGGGCCAGGGAGGGCCTCTTGGGGAATATCTGAGGCTCTGTGGTCACCAACAGACCAGTTACTCCTTTAGGTGTCTGGAGAAGGGGTCAGCTGCCTGTATCCAGTCAGGGATCTCAGGCAGAAGCTGTTCCCAGAAAGAAAAGGCCAGGGGGCAGCCTGGCTTGGCCCCGAGCCCTGAGCCCCCCAAGCCCCAAGCCCCTGATCTCAGCTGGCAGCCTCCTGGGTGATGGAGCTGTCTGTAGTTACAGGCCCATAGTTGACTACATCGATGCGCAGTTTGAAAATTATCTGCAGGAGGAGCTGAAGATCCGCCGCTCGCTCTTCGACTACCATGACACAA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003468 REGULATORY REGION Promoter description: septin 8. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.567901235 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.830303199 HeLa: 1.167367501 HT1080: 1.049412087 MRC5: 1.295561336 JEG3: 1.262074393 U87: 1.762915167 G402: 1.425479481 HCT116: 1.347917881 CRL1690: 0.950182854 AGS: 1.143123016 Panc1: 1.524870854 HMCB: 1.315959757 MG63: 1.260917199 Snu-182: 0.981570092. Number of positive cell lines: 0. Mean: 1.389377782. Mean(log): 1.236975344. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 540614 LOC540614 NCBI 2034 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TTCCCAGAAAGAGCAGAGAGAAAGGCAGAGGGAAGAGAAAGAAACGGGGTTTCAGAGGATTTGGGAGCTGCTTTTGTATAGATTGTCAGTGAGAAGGATACAGAACCTCCTGAGGCCTCCGACCCTGGCGTAAGTGTTAATTTTCTGAACGTTTTGAGCAGTGACATTAGCGGAGAGAACGTGCACGCACTGGGAGTGGTCATCCTCTTTGCACAATGGTGGAACCATTAAGACGTTGTCCCAAGCCCTTGGGACAGGCAGGGTGATGGACACTTGCAATCTGACGCCTTGACCGTCGAGCTCCGCTTTTCTATTGCAGGAATCCCAGCCTAAACTGCGCATCCTGCTCGTTGGTTGCACAAGGAGCCGAAGGCTGGTCCCTTGCCCGGGAAGGCCGCCTGGCCGGACGCGCGGGTCCCGCCGGGGTTCCCGCCTTAGCTCCGGCCGGAGCATCAGGTGGGGCCCAAGACACCCGCAGACTAGGCT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003469 REGULATORY REGION Promoter description: apical protein 2. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.540892193 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.22325663 HeLa: 0.652114321 HT1080: 1.005200373 MRC5: 0.887428301 JEG3: 0.356191783 U87: 1.07637907 G402: 0.899083612 HCT116: 1.303438086 CRL1690: 0.914908207 AGS: 0.821843043 Panc1: 0.767378185 HMCB: 0.77998444 MG63: 0.611103441 Snu-182: 0.95155275. Number of positive cell lines: 0. Mean: 0.775109657. Mean(log): 0.803561589. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom NM_133456 NM_133456 USER DEFINED 2035 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ttccctctcagaacctcattgtccttgtctgtaaaatgcagacagcagttgcaacgatcaaaataaatatttatataaagcacctggaacataacaggcacagagGGAGGGAGGAAGGCTGTGAAGCTGCCTCTGCCCCTTGCCCTGGGTCTTCCCCCACCCCTCCTTTCTTAGCTCCCCTGAGGTCACAAGAGTGTTCTTGACCATTGTTTATCAGGGAAAGATCACATGGAGAAGCCAACAGAACGGCCAGGAAGCAGCCTGGGTGGAACAGGGTTGGGGAGGAAAGGAACATGGGTACATTCTCAGCGTTCCAGGAGGTCTCAGGGTAAAGGCTGCTTGTGTGGGCAAGGGGAGCCTGGCAGGGAATGAGCTGGTCCCAATTCCTTCCCCTGAGCTGGGCCCTCAACCTTCAGAGGTGCTCCCTGGGACTGGTCCTACTTCCTCTGCCACCTCTGATCCCAAGGTGACTCTGCCAAAATCTGGGGGATGCCAGCGCTTGTGACGGTGTGACCAGGGAGGGGAAGTGTAAGTGTCT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003470 REGULATORY REGION Promoter description: growth differentiation factor 9. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.406882591 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.193607646 HeLa: 0.47439339 HT1080: 0.48027394 MRC5: 1.147912978 JEG3: 0.470109289 U87: 1.12396395 G402: 0.735919587 HCT116: 0.82417701 CRL1690: 0.390809364 AGS: 1.486142417 Panc1: 0.552621851 HMCB: 0.671402023 MG63: 0.459965352 Snu-182: 1.161376508. Number of positive cell lines: 0. Mean: 0.709188846. Mean(log): 0.726619665. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 2661 GDF9 NCBI 2036 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence GCCTTAGAAGTTTCAGCAAGCACCTAGCGAACATCTTAATCCAAATTTCTCAAAAAATGAGAGATTTTATTTAAGATCATTCCTCAATTTATCTTAGACTTTCAGCTACATAGTTAGTCCGGTAGTGTAACAGTAACGGGTTTTACGTAAATGCCAGGGGAAAAGAGAGGAAAGCTAAATAACCAAGTAAATCTGTATCTAATTAACAAATTGGCTAAATAAGGTGTTATCAGCTGCTTGATATAGAGCTGATAAAATCTTCAGCTAGGCATACTTGAGGCCTGATTACAGAAGTGACCGTAGTCCACCCACACACCTGAAATTTATTTAAGAGACCAAGCTAGGCTCTTCCTGGCCTTTAGGAAGAGGACTGGCATGGAGAAATATGTTCCTCACTAGTTCTCCCAAGCCATGGCACGTCCCAACAAATTCCTCCTTTGGTTTTGCTGCTTTGCCTGGCTGTGTTTTCCTATTAGCCTTGGTTCTCAGGCTTC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003471 REGULATORY REGION Promoter description: low molecular mass ubiquinone-binding protein (9.5kD). This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.621900826 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 9.567755078 HeLa: 8.835929937 HT1080: 9.717385188 MRC5: 7.270095055 JEG3: 10.47664533 U87: 10.04330927 G402: 6.806393463 HCT116: 7.522809329 CRL1690: 9.786151579 AGS: 10.80922439 Panc1: 6.194615991 HMCB: 10.16764906 MG63: 9.039309518 Snu-182: 5.976741944. Number of positive cell lines: 14. Mean: 675.9837823. Mean(log): 8.729572509. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC064949 BC064949 USER DEFINED 2037 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CTGTCTACAGCTGGGAAGACTCGCAGGCCCCAAGCTCCTGGCCAGCGCTGCCCCGGAGGTCGGCAGGCCCCTTCCTCGTCACCTTTTTGTTCCCTCCCCCGCCTCCCGCATTCGGCCGCTTCCTGACTGGGATTCCACAGAAAAGCCGAGGGCTGAGGAGAAGTGTGAGCGCCTCCGCCTGTCCACTGTCCCCCAAAGTCAGTTCAATCCCCGACGTCCTCCGCTAGGCTCCACCCCACCGGCCCGGGCAGGGCCTCCAAGGCACCTCCCACCTACGGGTCACCCAGTCAGCCCACTTCTTTCTGGGACAAAGGCGTCATCCCTTAGAGACAGTAGGAAAATGGTATCTCCCGGAAGTTACCTCACGACCTCCAAGAGCGGCTTCCAACCTTGCCGGAAATGACGAACGAGTCAACCGGATCGGTGACTGTGGAGGGCGAGCTGAGCCCTGTGCGTGAGTGGGGTCTGGTTGTGCAGTGTTCGT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003472 REGULATORY REGION Promoter description: liver-expressed antimicrobial peptide 2. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.488469602 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.291649932 HeLa: 1.054477963 HT1080: 0.751191021 MRC5: 1.021797646 JEG3: 0.488407357 U87: 1.465086727 G402: 0.817065291 HCT116: 1.057722576 CRL1690: 0.790928854 AGS: 0.614256534 Panc1: 0.818148708 HMCB: 1.042319713 MG63: 0.712618638 Snu-182: 0.953410193. Number of positive cell lines: 0. Mean: 0.834332034. Mean(log): 0.848505797. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom NM_052971 NM_052971 USER DEFINED 2038 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence AGGCAGAAATGGAGGATTAGGAGAATTACTCATCTTTTGGATGAACAGTTTCCAAATCCCATTTGGCACATCACTCTAGACTGGTAAAGGGGAGGCTGACACTGAGGCCACAGACCCAACTGGCTCTAGGACATCACGTTGTTCAGTCCTTTGCTTATCTAATCATTTGTGTTCTTACCCAGTGCTCACTAGGTCACCCACATAGCCACTTCCCCTCCCAGCAAAAGTTCCCAGTTTAGGCACCTGTCTGGGATCATCCAGTATCCAAGCTTAGGGGTGAAGGGAGGGAGCAGAGAACTAGTCTCAACTGGTTCGTTGGTATATAGGTCTCTTCTCAATGTTCCTAAAGTGCATGCAGTGGCATCCCCCTCAAGGCCTGGCTCCATGATTCTGAGAGGACTAGAATCAGGACAGTCAGATCTGTGGTCACATCCTGCCCAATTCCAGCTCTGAGGTCCATCAAACCATCTGCTTCTC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003473 REGULATORY REGION Promoter description: ALL1 fused gene from 5q31. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.339181287 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 1.170235255 HeLa: 0.705697404 HT1080: 0.59415296 MRC5: 0.932381858 JEG3: 1.111591709 U87: 0.962418396 G402: 0.807628935 HCT116: 1.021424403 CRL1690: 1.194764637 AGS: 1.220457061 Panc1: 1.116508147 HMCB: 0.882254385 MG63: 0.948713256 Snu-182: 0.796109261. Number of positive cell lines: 0. Mean: 0.963314686. Mean(log): 0.961738405. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 27125 AFF4 NCBI 2039 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TTAATGTTCAAGGGTGCAATGTGTATTCCTTTAGATTGTTAAAGCTTAATTACTATGATTTGTAGTAAATTAACTTTTAAAATGTATTTGAGCCCTTCTGTAGTGTCGTAGGGCTCTTACAGGGTGGGAAAGATTTTAATTTTCCAGTTGCTAATTGAACAGTATGGCCTCATTATATATTTTGATTTATAGGAGTTTGTGTCTGGGTCCCAGGAACATCTACTGGGGATGACTGTTAGGCAGCTTGTGATGATGTTTTTTAAAAAACCTAAGTAACTTGGGGAGACAGAGCATTTCAAACCCATATAGACACCTATCATACCTGTATATCCCCTAATACATGGAACATAAATTTCATTTCAGCTTTATGCATTAATGTATTGAAGAGGCAGGCTTTTTTTCCAGTAATAATACTGTACATCTAAGGTTGCTATTCAGTAAAACTAATAGAAGAGATAATTATTGAATACCTTGGAATATGTAGTGAGAAGAGGCCAAATTTTTCATGTTTGT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003474 REGULATORY REGION Promoter description: ALL1 fused gene from 5q31. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.307692308 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.40467723 HeLa: 0.401824624 HT1080: 0.56848237 MRC5: 1.168210172 JEG3: 0.622259356 U87: 0.990729429 G402: 0.405972953 HCT116: 0.682440698 CRL1690: 0.207198092 AGS: 0.638609973 Panc1: 0.357111156 HMCB: 0.846423107 MG63: 0.500114407 Snu-182: 1.167889421. Number of positive cell lines: 0. Mean: 0.591635013. Mean(log): 0.640138785. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK129636 AK129636 USER DEFINED 2040 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence caagtttatcttgccaaatcccaggtcatttagatttggcattgtgtttttttctaaagattttatagctctagcttttacatttataggtctttgatccttcttgagttttttgttttgttttgttttgtttttaatatgatgtgatataaaggcccagctttattttgcccatggatattcagtttgtccagcaccgttgttaaaaagactattctttcccatataatggtcttggcatcctcttggaaaatcagttgaGTGTAGAAATAGGTTTTTAATGTTTTTTAACCGCAAAACTATATTTTAGCTTTCTAACTATTTGGATTGTTCTTTCACAGACAATTCTGTAACTAAAGGAAGATTATGCTTATTTTTAAGTAAGCTTTTAGGAATATTTGTATAATTTTAGTGCTACATCTTGTATCCAGATTTAATTTTGAGAAATGCATAGTTTGCACATATGGAACAGCTGTTCTGGTCATGAAAATTGA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003475 REGULATORY REGION Promoter description: "interleukin 3 (colony-stimulating factor, multiple)". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.55179704 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.423515044 HeLa: 1.465054399 HT1080: 2.46789168 MRC5: 1.338403549 JEG3: 1.135855936 U87: 3.32432624 G402: 1.401731754 HCT116: 2.408386081 CRL1690: 1.778915016 AGS: 2.574528184 Panc1: 1.506131853 HMCB: 1.962447358 MG63: 0.748487854 Snu-182: 0.989294593. Number of positive cell lines: 4. Mean: 2.722820634. Mean(log): 1.680354967. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 3562 IL3 NCBI 2041 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CGGCTACCAGACAAACTCTCATCTGTTCCAGTGGCCTCCTGGCCACCCACCAGGACCAAGCAGGGCGGGCAGCAGAGGGCCAGGGTAGTCCAGGTGATGGCAGATGAGATCCCACTGGGCAGGAGGCCTCAGTGAGCTGAGTCAGGCTTCCCCTTCCTGCCACAGGGGTCCTCTCACCTGCTGCCATGCTTCCCATCTCTCATCCTCCTTGACAAGATGAAGTGATACCGTTTAAGTAATCTTTTTTCTTGTTTCACTGATCTTGAGTACTAGAAAGTCATGGATGAATAATTACGTCTGTGGTTTTCTATGGAGGTTCCATGTCAGATAAAGATCCTTCCGACGCCTGCCCCACACCACCACCTCCCCCCGCCTTGCCCGGGGTTGTGGGCACCTTGCTGCTGCACATATAAGGCGGGAGGCTGTTGCCAACTCTTCAGAGCCCCACGAAGGACCAGAACAAGACAGAGTGC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003476 REGULATORY REGION Promoter description: colony stimulating factor 2 (granulocyte-macrophage). This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.570576541 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 1.24197825 HeLa: 0.947245852 HT1080: 3.810574992 MRC5: 1.576447004 JEG3: 0.487496139 U87: 3.421514652 G402: 1.266512191 HCT116: 2.756370393 CRL1690: 1.915390427 AGS: 3.716137108 Panc1: 1.68978451 HMCB: 1.474859549 MG63: 1.442497696 Snu-182: 0.933243224. Number of positive cell lines: 5. Mean: 4.009568068. Mean(log): 1.905717999. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 1437 CSF2 NCBI 2042 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CCCTCACACTCAAGTCTCTCACAGTGGCCAGAGAAGAGGAAGGCTGGAGTCAGAATGAGGCACCAGGGCGGGCATAGCCTGCCCAAAGGCCCCTGGGATTACAGGCAGGATGGGGAGCCCTATCTAAGTGTCTCCCACGCCCCACCCCAGCCATTCCAGGCCAGGAAGTCCAAACTGTGCCCCTCAGAGGGAGGGGGCAGCCTCAGGCCCATTCAGACTGCCCAGGGAGGGCTGGAGAGCCCTCAGGAAGGCGGGTGGGTGGGCTGTCGGTTCTTGGAAAGGTTCATTAATGAAAACCCCCAAGCCTGACCACCTAGGGAAAAGGCTCACCGTTCCCATGTGTGGCTGATAAGGGCCAGGAGATTCCACAGTTCAGGTAGTTCCCCCGCCTCCCTGGCATTTTGTGGTCACCATTAATCATTTCCTCTGTGTATTTAAGAGCTCTTTTGCCAGTGAGCCCAGTACACAGAGAGAAAGGCTAAAGTTCTCTGGAGGATGTGGCT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003477 REGULATORY REGION Promoter description: "procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.558333333 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.576606195 HeLa: 0.795983058 HT1080: 1.292209055 MRC5: 1.307593006 JEG3: 0.689413451 U87: 1.384909711 G402: 1.020224155 HCT116: 1.284731907 CRL1690: 1.173943511 AGS: 1.165198414 Panc1: 1.592741549 HMCB: 1.372562274 MG63: 1.689324044 Snu-182: 1.105590566. Number of positive cell lines: 0. Mean: 1.308718148. Mean(log): 1.175073635. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 8974 P4HA2 NCBI 2043 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence AAGTCTTTTCTCCCCCAGACATCCTTGTGGAACCAGCGTTGTTTTTCCTTGGCAGCTGCGGAGACCCGTGATAATTCGTTAACTAATTCAACAAACGGGACCCTTCTGTGTGCCAGAAACCGCAAGCAGTTGCTAACCCAGTGGGACAGGCGGATTGGAAGAGCGGGAAGGTCCTGGCCCAGAGCAGTGTGGTGAGCGCTGTGCTGGAAGGGAATGCGGGCAGTGGGTACTTGGTAGAGCACTGACTGCCTCCGGCCAGAGGACTTCCCGGAGGAGGTGACCCATGAGCTGGAGTGGTCAGAGGAAGGCTGGCAAAAGGGCATCGTGGACAGAGGAACAGCCTATGTGAGTGGGAGCAGAGACCTTGGCCAATGCCATTCCTTATGGCCTTGTAGTGGAAGCAAGGTGATGGGGAAGGAACACTGTAGGGGATAGCTGTCCACGGACGCTGTCTACAAGACCCTGGAGTGAGATAACGTG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003478 REGULATORY REGION Promoter description: "procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.743636364 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 6.149162706 HeLa: 4.802430284 HT1080: 5.438170142 MRC5: 4.316000741 JEG3: 4.7788327 U87: 4.605608252 G402: 4.968886356 HCT116: 4.300849832 CRL1690: 3.662433751 AGS: 4.450705959 Panc1: 4.991518657 HMCB: 4.82102634 MG63: 4.626144745 Snu-182: 1.529002987. Number of positive cell lines: 13. Mean: 26.65459393. Mean(log): 4.531483818. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 8974 P4HA2 NCBI 2044 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TAACAGCCTCCTTGTGGTGGTGCTGGGAAGAAGGGGCCCGTGTACCCGGCAGGGCCCCCCAGGCAATGGGCATGAGCGCAGGCAGGGAAATCCGTCAGCCTCCAGGGACGCTCTCCCTACAGCCCCGGCGAGGGGATCGGGTCGTGGCGACCTCTCCAGACGCCCAGGGGCTGGGCAGGAGGGCGGGCCAAGGCCCGCAGGTGGGGGCGCCAAAGCCAGGCGGGCGCGGAGTACGTGCGGTGGGCTGCGGGCGGCATGAAGGGCGCGGGCGGCCAGCTCCGGCTCCGGCTCCGGCTCCGGCTCCCGCGAGGCCGGGTAGCCTGGGCGTTCCCAGGGGTCGCAGAGGACGGCGAACCCCGGCGGAGCCACCGGAGCTGGGGACCAGGACGCAGGCAGGCGTGTGGAGCGTGAGGTGGGGACGTGGCGGCGGCTCAAGTGGGCGGAGCCCCGGCAGCGGCCCGAGGCGGAGTCGCCAAGGGAGGAGGCGCCGAGCTGACCGGGCGACGCCGCGGGAGGTTCTGGAAACGCCGGGAGCTGCGAGTGTCCAGGT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003479 REGULATORY REGION Promoter description: PDZ and LIM domain 4. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.733059548 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 2.937871764 HeLa: 1.805311616 HT1080: 2.792074732 MRC5: 1.653564005 JEG3: 0.910379751 U87: 1.609698132 G402: 1.562533021 HCT116: 1.578347643 CRL1690: 1.236307026 AGS: 2.021877758 Panc1: 1.416216824 HMCB: 2.574886125 MG63: 2.602532933 Snu-182: 1.060762249. Number of positive cell lines: 5. Mean: 2.95038007. Mean(log): 1.840168827. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 8572 PDLIM4 NCBI 2045 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TCATAGGGTTCTTGGTTCAGAGGGCTCCTCACACGGCAGGATGGGCCGCAGGTGTGCCAGTCGGGCCCATGAGGAGGTATCTGAGCTGGGGCAGCCCCATCCCCCAAGTGGGCCCTCCATCCCTCCTCGGGCTGGAGCACCGCCCCTAAAAGCGACTTCAAAGGGCCGGTGTCGACAGCTGGGTTTGGGTCCGCGGCCTGCAGATCCAAGGCCCGAGCAGGATCCAGGCCGTCGGGGCCGTCCGAACGCGGGGATCTCTGAGAGCTGAGTGGGGGTGCCGGGTTGCCGGCAGCCGGGGCTGAGGGCGGGTCCTCAGAGCCCCCCGAAGTGGGAGGGTCGGGCTGGCCGCGGGGCCAATCCAGGCGCACAgggagcgggggcgggggctgggccgagtggggacaggggcgggcgggccgggggcgggcgcggCGTCCAggcggcggcggcggctgcggcggcggcggcTCCTCCTCAGAGTCCGGCT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003480 REGULATORY REGION Promoter description: hypothetical protein MGC13125. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.656387665 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 7.003557916 HeLa: 5.642434964 HT1080: 6.81542125 MRC5: 3.881425776 JEG3: 5.668638945 U87: 6.826540353 G402: 4.083496689 HCT116: 4.660125954 CRL1690: 6.489046682 AGS: 6.512880796 Panc1: 4.51629849 HMCB: 9.056370535 MG63: 5.142896329 Snu-182: 1.95001935. Number of positive cell lines: 14. Mean: 90.99020568. Mean(log): 5.589225288. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom NM_032725 NM_032725 USER DEFINED 2046 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence cagtattcaaactcggctacgctgcagcccgtggccctccactTTCTTGCTCGTGCTCTGGAGTTTAGGCGGCCGATGGGGGCGGGGTCCTTTGGGTCAGGTTGTGGCCTCATAGAACAGCGCTTGCTGCGGTtggatggatgggtgggtgggtgggtgagtgAATGAAGAGAAGAAACCTGGTGGCGTCGTCCCAGGGCTGTGGAGCGCCCCGAAGGTGCGCACGTCCCTGGCTAGCCTGCGAGCGCGTCCCGGTGGCCGCACCTGCCAGCCGCGCGATTCTTAGCACTCTCCGCCACTTCCGGCCGTGGCCCCGCCCTGTCGGGTGGCTGGCGTCCGTTACGCGTTGAGGCATTTTGTCCCCAGCGCCGACCCGTCTCTCTGCCCCCGCCGCTGCCATGGCGGCAGCTCCGCCGCTTTCCAAGGCCGAGTATCTGAAGCGTTACTTGTCCGG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003481 REGULATORY REGION Promoter description: "Clone IMAGE:5288763, mRNA". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.427368421 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 1.718115734 HeLa: 1.298819232 HT1080: 0.911561556 MRC5: 0.998989122 JEG3: 1.894541651 U87: 0.904511984 G402: 1.267970482 HCT116: 1.264472322 CRL1690: 0.913869493 AGS: 1.295732911 Panc1: 1.235012939 HMCB: 0.998645492 MG63: 1.317510989 Snu-182: 1.090938828. Number of positive cell lines: 0. Mean: 1.381724044. Mean(log): 1.222192338. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC042385 BC042385 USER DEFINED 2047 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TGGCGAACTTTAAAACCATCAGTGATTTGAGTTAATTCTACCTGTTTTACCTTATTTTTCACCAGTGTGTGTTTCCTCACTGCCTCATTATATTGCCACATTTAATCTTTCATTAAAACAAACAAACAAACACAACTCTTggctgggtgtggtggctcacacctgtaatcccggtactttggaaggctgaggtgggaggattccttgagttctagaccagcctggtcaacatagggagattctctctctcctgaaaaaaaaaaaaaaaaaaaaaaattaaccaagcatggtggcacacatctgtagtcccagctactcaataggcaaagtgagaggattgcttgagcctgggaggttgaggctgcagtgaacatgatcaaaccactgcattccagcctggaggacagagcgagaccctgtcttacaaaacaaaaCAACAACTCTTGGAATttctcttttcccctcccttcttctt 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003482 REGULATORY REGION Promoter description: "Clone IMAGE:5730164, mRNA". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.488372093 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: Bad Txfn HeLa: 2.659656589 HT1080: Bad Txfn MRC5: Bad Txfn JEG3: Bad Txfn U87: Bad Txfn G402: Bad Txfn HCT116: Bad Txfn CRL1690: Bad Txfn AGS: Bad Txfn Panc1: Bad Txfn HMCB: Bad Txfn MG63: Bad Txfn Snu-182: 1.13018838. Number of positive cell lines: 1. Mean: 3.253849708. Mean(log): 1.894922485. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC035670 BC035670 USER DEFINED 2048 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ttacaggtgacaaaacagcctcagagaggttaCTTCCAGAAGGAAGCAGAGCTTTTTttttttttttttttttttttttttttttttgagacggagtctcactctgttgcccagactggagtgcagtggcgtgatcttggctcaccacaacctctgcctcccaggttcaagcgattctcttgcctcagccttctgagtagctgggactacaggtgcacgccaccatgcctggctaattttttttttttttttttttttggagacagtcttgctctgtcacccaggatggagtgcagtggtgcgatcttggctcactgcagccttgcctcctgggttcaagcaattctcctgcctcagcctcctgagtagctgggattacagacgcccaccactgcacccagctaatttttgtatttttagtagagatggggtttcaccatgttggtcaggctggtctcaaacccctgacctcgtgatccacctgccttggcctcccaaagtgcagggattacaggc 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003483 REGULATORY REGION Promoter description: zinc finger protein 259. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.597916667 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 9.402312863 HeLa: 8.272028735 HT1080: 7.974991839 MRC5: 6.552261215 JEG3: 8.734222141 U87: 8.829613033 G402: 5.343445087 HCT116: 6.514770632 CRL1690: 8.30972651 AGS: 9.271411015 Panc1: 5.182201445 HMCB: 8.027831946 MG63: 8.396107902 Snu-182: 4.422423533. Number of positive cell lines: 14. Mean: 280.07212. Mean(log): 7.516667707. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 8882 ZNF259 NCBI 2049 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence GAACAGAAAGGGACAGAGGGATTCAGGGATTGTGAGAGAGGGGAAGAGGCTGAGCCACCCGGAGGGGCGACCTAGCACGCAAGCAGTATGTGGCCCAACACTGGAACCAAGCAGCCCGGCTCCGGGCGCACCTTCTCAGGGATTCCTCAGGGACAAGTCCAGCCCCTTGTCGTCAAGGCTCTTGTAGACCGACGTAGGGACCAATAGAACCCCGTGCGGTGGAGCTATTGTGAAGGAGCAAAAAAGTGCCCTGGTTCTAAGAGGACGTCTTAGGGGAAGTGACGGCTGAGTTGAGGTGGATCCGGCTGGCGATGTAAGGTTCGAGCCATATAAACCCGGGAACCGGGAGCCCTTGACGACATTGTTCCCCGAGTGCCCGGAGTCTGCGGCTTTTTTTGGGGTGGTGGCAGCTGGCGGAAGTGACGGGAGAGGGGTGGGGCCGCGAGAGCGGCGGAAGTAGGAAGCCGAGGTCTGAATTGC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003484 REGULATORY REGION Promoter description: apolipoprotein A-V. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.582120582 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.915819604 HeLa: 0.433704691 HT1080: 0.379321447 MRC5: 0.881052486 JEG3: 1.167306956 U87: 0.583874974 G402: 0.715210778 HCT116: 0.88279258 CRL1690: 0.916482704 AGS: 0.708984486 Panc1: 0.34234911 HMCB: 0.677154037 MG63: 0.773576907 Snu-182: 1.280730613. Number of positive cell lines: 0. Mean: 0.724166177. Mean(log): 0.761311527. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 116519 APOA5 NCBI 2050 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TCTTGGAACATTTTGGCAGAGTTGCCTCTTCGCCCTCATTATGGCTCAGTTTTTCCACCATGAAATGGGAGGGAGGGAGACAGGTGGGCAGGGGAGAGGTGGTAGAAGTGGCCTAGAGAACTGTTCCTGGGGTCTGGGACCTTTGCGAAGGGGTTAGAGCACCACGCTCCCTGCTATGTGACTGAGGTAGCAAGAGCACGCCCTCTTCCCATGTCTGAGGAAGACACCCTAGCCTCCTTGACTCACCTAGGTCAGTCCTCTTGAGCCCCAACAGCTCTGTGCTCCCCAGCCCAAGGAAGGGGTAACAGGATTTCGGGCAGTTGCCCCTGCAGAGGCCCCCTGGGCAAGTCCCCTGCGCCATGTCCCTTCGTCTCCTTCTTCCCCTAACCAGGCCTCCCTCCACCTGTCTTCTCAGAGCAGGTAATGGCAAGCATGGCTGCCGTGCTCACCTGGGCTCTGGCTCTTCTTTCAGGTGGGTCTC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003485 REGULATORY REGION Promoter description: apolipoprotein A-IV. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.600840336 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 2.262998308 HeLa: 2.062093656 HT1080: 3.596407869 MRC5: 2.597641006 JEG3: 2.525981233 U87: 4.938386196 G402: 4.37804075 HCT116: 4.707572259 CRL1690: 3.83718316 AGS: 4.389766969 Panc1: 2.834929273 HMCB: 2.197993883 MG63: 2.793315707 Snu-182: 1.886686076. Number of positive cell lines: 11. Mean: 11.00550839. Mean(log): 3.21492831. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 337 APOA4 NCBI 2051 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CACTGGGGTAGACAGAGGAGATGTGGACTTTGCCCCCCATGAGCCCGGCACAAACCCAGAGCCGCCAGCAGGGCCTCGAGGCATCAGTCCCGGGCTCATGGGCTCCCTGAGGTGTTTCTCCTACTGTTTTCCGTTCCCCTCCTCCCTTCCATGCTGAGGTTGGTGGGGTGGGGGTGGGGGTGCCCACGCACGGAACAGCCACCACTTCTAACTATCGCCTGAGCCCTGATCTGCTGTCAGCTTCCACGTAGTCTCAGGGTCACAAAAGTCCAAGAGGCCTCTTGGGAATGTGTCACCTTCCAGCGTGGAGTCACACTGAGGAAGGAGGAGGGGAGGGCAGCCAGGGGGGTGGCGATAGGGAGAGAGTTTAAATGTCTGGCTGGCTCTGAGCTTCAGTCAGTTCCCACTGCAGCGCAGGTGAGCTCTCCTGAGGACCTCTCTGTCAGCTCCCCTGATTGTAGGGAGGATCCAGTGTG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003486 REGULATORY REGION Promoter description: apolipoprotein C-III. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.613537118 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 2.638472718 HeLa: 1.728416633 HT1080: 2.033489258 MRC5: 1.539692959 JEG3: 2.385366696 U87: 2.35167165 G402: 2.334979113 HCT116: 2.301912993 CRL1690: 1.057184419 AGS: 2.119572055 Panc1: 1.591109098 HMCB: 1.704625272 MG63: 2.631773812 Snu-182: 1.087788806. Number of positive cell lines: 5. Mean: 3.133515549. Mean(log): 1.964718249. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 345 APOC3 NCBI 2052 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TGTTCTCAAGTCTGAAGAAGCCCCTCACCCCTCTACTCCAGGCTGTGTTCAGGGCTTGGGGCTGGTGGAGGGAGGGGCCTGAAATTCCAGTGTGAAAGGCTGAGATGGGCCCGAGGCCCCTGGCCTATGTCCAAGCCATTTCCCCTCTCACCAGCCTCTCCCTGGGGAGCCAGTCAGCTAGGAAGGAATGAGGGCTCCCCAGGCCCACCCCCAGTTCCTGAGCTCATCTGGGCTGCAGGGCTGGCGGGACAGCAGCGTGGACTCAGTCTCCTAGGGATTTCCCAACTCTCCCGCCCGCTTGCTGCATCTGGACACCCTGCCTCAGGCCCTCATCTCCACTGGTCAGCAGGTGACCTTTGCCCAGCGCCCTGGGTCCTCAGTGCCTGCTGCCCTGGAGATGATATAAAACAGGTCAGAACCCTCCTGCCTGTCTGCTCAGTTCATCCCTAGAGGCAGCT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003487 REGULATORY REGION Promoter description: apolipoprotein A-I. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.626 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 7.734055597 HeLa: 2.826770438 HT1080: 3.492404187 MRC5: 2.004008787 JEG3: 1.951000297 U87: 3.125281844 G402: 3.289976238 HCT116: 2.643197494 CRL1690: 1.759152107 AGS: 2.81830397 Panc1: 3.200588438 HMCB: 3.505374474 MG63: 2.589905753 Snu-182: 1.570539742. Number of positive cell lines: 12. Mean: 20.70445509. Mean(log): 3.036468526. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 335 APOA1 NCBI 2053 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence AGGGGAGTGAAGTAGTCTCCCTGGAATGCTGGTGGTGGGGGAGGCAGTCTCCTTGGTGGAGGAGTCCCAGCGTCCCTCCCCTCCCCTCCTCTGCCAACACAATGGACAATGGCAACTGCCCACACACTCCCATGGAGGGGAAGGGGATGAGTGCAGGGAACCCCGACCCCACCCGGGAGACCTGCAAGCCTGCAGACACTCCCCTCCCGCCCCCACTGAACCCTTGACCCCTGCCCTGCAGCCCCCGCAGCTTGCTGTTTGCCCACTCTATTTGCCCAGCCCCAGGGACAGAGCTGATCCTTGAACTCTTAAGTTCCACATTGCCAGGACCAGTGAGCAGCAACAGGGCCGGGGCTGGGCTTATCAGCCTCCCAGCCCAGACCCTGGCTGCAGACATAAATAGGCCCTGCAAGAGCTGGCTGCTTAGAGACTGCGAGAAGGAGGTGCGTCCTGCTGCCTGCCCCGGTCACTCTGGCTCCCCAGCTCAAGGTTCAGGCCTT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003488 REGULATORY REGION Promoter description: KIAA0999 protein. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.44375 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 3.045617686 HeLa: 2.150530385 HT1080: 2.106632075 MRC5: 1.204832364 JEG3: 2.524683575 U87: 1.940151173 G402: 2.197791875 HCT116: 2.871575978 CRL1690: 1.442531987 AGS: 2.332943141 Panc1: 1.849774488 HMCB: 1.95292883 MG63: 2.622243897 Snu-182: 1.173162528. Number of positive cell lines: 5. Mean: 3.603689745. Mean(log): 2.101099999. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC063887 BC063887 USER DEFINED 2054 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence aatgagggcaaggtctatgtctgtaaattcacattttatccTGTAACAGTAAGCATTTGGCTATTTGTTAGATTAATAAATGAATGAATGAAGATAAATAAGAGGAAGAAATTCTAATTAGTATTACCTAAGCAAGGTAAAAATGGAAAAATAGGTATATGAAAATCCTGTATAACCCAGGAGTCTAGAAAAGTTCTGTAAATAAGAAAGTTAACAGAAAGTCCTGCCCCAAGCCCAGTTACTAGAGTAAGAGGCATGACAGAATAAGCTGCCACCTTGAGCTTTTCCTTCCTGTCTCTCTTCAGGCAGTGCCAGCAGTTACCCCTGTGGACGAGGAGAGCTCAGACGGGGAGCCAGACCAGGAAGCTGTGCAGAGGTAATGTGACATCTGGCAGTGCTTGCAGAAGCCCCTGGGCAGGCTCCCCTGCAACCAGCGAAAGGTCACCTCTGCCCAAGGAGGTGGTAGAGTGCAGCTTCAAC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003489 REGULATORY REGION This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.41356674 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.21638067 HeLa: 1.009079117 HT1080: 0.253882431 MRC5: 0.961006615 JEG3: 0.3981989 U87: 0.927392265 G402: 0.594517319 HCT116: 0.608064141 CRL1690: 0.570202099 AGS: 0.524940355 Panc1: 0.363464141 HMCB: 0.698542719 MG63: 0.15036299 Snu-182: 0.978541961. Number of positive cell lines: 0. Mean: 0.534335764. Mean(log): 0.589612552. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK122838 AK122838 USER DEFINED 2055 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CAAATGAGCAACTGCATCAGAACCGTTCCTCTGAGGTTACTGTGCTGGACTGACCTGGGTATCAGTCTCTTCACAACCTGAGCTTCTGAAAAAGTCATGAAATACCTGGACCTGGGATTTTCTGTGATGGGAGAGAATTATTTTTGTGCAGAAAGACTGTATTGCTACTTGAAGAACATGGCTTTCTGAGGGGATCAGAAACATGTCCATTTCAGAAAACATTGAAAGCATAGGAATCAAATTTTAGGAGAAAATAGTACTTACTTGCTTCTACTTCAACCTGAAGTAGAAACAGAAATGACAAGTTATAAGGAAATGCTTCTCAACACAGCCTTCATGATCCCTGTTCCTGGATTGTGGCCCGCCAAATTCATTTGTTTTTTGTGTTGCTGAACCAAATACATGTTCGTGCTCATTTCATTAGCTCACTGCTGGGTCAAGCCTCAGGTAGAGTCTG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003490 REGULATORY REGION Promoter description: KIAA0999 protein. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.511904762 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.398295335 HeLa: 0.61654993 HT1080: 0.93236559 MRC5: 0.888059455 JEG3: 0.561587536 U87: 1.08702517 G402: 1.054655963 HCT116: 1.075186977 CRL1690: 0.606710536 AGS: 0.651358574 Panc1: 0.88963639 HMCB: 1.164584755 MG63: 1.020063938 Snu-182: 1.170284592. Number of positive cell lines: 0. Mean: 0.847221638. Mean(log): 0.865454624. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK022302 AK022302 USER DEFINED 2056 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence agggaacttgttggaaacacaaattcttaggggcccatcctgacctactgaatcagagtttgaaacagaattatatagataggacccaggaatcttctgtttaacaagttctccagacttgtcctatgctcagtgcagtttgagaagcactgTTCTAGCTGGTATGTCGTCTGAGTATTCTCATTAGCTCTCATTACTTCTGGCTGGCTGGTGGCCTGGGCACTTGGTCACTCTGAGGTTCCTTTCTCTCCAGGGGCTGCATCTTCTTCCCAGTTTCAAGGCTTACCTTCCCGCAGTGCAATCTTTCAGCAGCAACCTGAGAACTGTTCCTCTCCTCCCAACGTGGCACTAACCTGCTTGGGTATGCAGCAGCCTGCTCAGTCACAGCAGGTCACCATCCAAGTCCAAGAGCCTGTTGACATGCTCAGCAACATGCCAGGCACAGCTGCAGGCTCCAGTGGGCGCGGCATCTCCATCAGCCCCAGTGCTGGTCAGATGCAGATG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003491 REGULATORY REGION Promoter description: KIAA0999 protein. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.408839779 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 2.50703912 HeLa: 2.169739838 HT1080: 2.539579283 MRC5: 1.15199757 JEG3: 2.570637081 U87: 1.95547235 G402: 2.128208774 HCT116: 1.849147569 CRL1690: 0.952321536 AGS: 2.153360791 Panc1: 1.731839153 HMCB: 1.505615538 MG63: 1.446453966 Snu-182: 1.155929671. Number of positive cell lines: 3. Mean: 2.822310535. Mean(log): 1.844095874. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC035583 BC035583 USER DEFINED 2057 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CCATCAGCTCCAGAGGTATGAGTCATTTTGTGTTGTGCCTAAGCCATTGTCTCGATAGCCTGGTACCCTTGGCTTGACTCACTGGGAGATATGGACTGACTTGAGCATTCATCTTGCAAGAATCTATTTGAAAAGGAGAGAAACCACTGTAAATTTCAGGAGCCTTCTTGAAATCCCAACTTCCTGTGCCACTTCATTTCCTTAGCCCCATGAGCAAAGTAATCTGATATCTAATACAGGAGCCAGACATAGGCCCACAATGAACTCTGCCATTTTGGCTGAGTTCTTTTCAAACAAGATGTAGATAGGTTTTAAATACACTGTGGTGGATGGCTTATGTATATTTTTCTAACATGAGGCTTATCAAAGTAAAAAAAAATAGTTTCCACTGATATATGTTGTATGGCTGAAACTTAAGATTGTACTGTCACCTTAGGAAGCTTCTTTGTGTATCTCTTTTGTTATTTTTAAGGTTAAGGATTCAGCCTTCAAGCCCACCCCCCAACCACCCCAACAACCATCTCTTCAGGCAGCCCAGTAATA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003492 REGULATORY REGION Promoter description: "CDNA FLJ25293 fis, clone STM07384". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.390852391 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.191859198 HeLa: 0.481230879 HT1080: 0.626506236 MRC5: 1.187111553 JEG3: 0.41081162 U87: 1.127491913 G402: 0.574256272 HCT116: 0.566686005 CRL1690: 0.637019512 AGS: 0.46823744 Panc1: 0.303774266 HMCB: 0.626419874 MG63: 0.321444885 Snu-182: 1.139868279. Number of positive cell lines: 0. Mean: 0.572358716. Mean(log): 0.618765567. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK058022 AK058022 USER DEFINED 2058 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ttcctaaccttaagcgatcctccctccttgacctccatgagccactgcgcccagccAGCaaacaatttttttaaaaaagcaaaacttaccttactatgtacagtgcatttcaatatattttattctattccattttaaaaaatgctgatttcgacttactaaattgatctcCTATCTGCTATTTCAGAAACAATGACATAGAAATACCTTTATAACCTGACTCCTGCCTAGCTCTTCAGCCCCAGCTCCCACTCTCCCACCAGTCACCCTAATTTTCTTCTCGTTCCCTGAACAAGTTCTGTTTTCTGGAGCATTTCCCACTGCCGAGAATACATCTTCCCTATCCCACCCCACTCCACCCACTCCTGTATTCTAGAATTCAGAATAAAAAAAATTAGATTGGATAGAAATAAGAATCTAGATAATTTCTATTCACTCTTCATGTCTCTAAACTTTCTCTTATCGTGGTGCTTACCAAGCT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003493 REGULATORY REGION This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.471349353 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 2.251623288 HeLa: 1.977960879 HT1080: 1.478933451 MRC5: 1.210251808 JEG3: 2.238482654 U87: 1.723764577 G402: 1.842043092 HCT116: 1.96287029 CRL1690: 0.93126922 AGS: 1.311046576 Panc1: 1.403862182 HMCB: 1.487066383 MG63: 2.023014737 Snu-182: 1.310042413. Number of positive cell lines: 0. Mean: 2.263537079. Mean(log): 1.653730825. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 9681 DEPDC5 NCBI 2059 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ACTTCTGCCTTCCTCCTCTTTGTGGTTGCCTTGCTCAGGACATTGGCAGCAAAACGAGAATGGTGGGAGTGTCTCTTAAGTCTCGAgtgaccttgagcaagtcccttgcccggagtcacactttcatcatctacaaaatgagtgggctaacctcttttaagatctcttTACTATTTGGGTGTTATTGGTGTAGATGGAGACAAGGTGATGAGCACCCATTCAGCGCAATGCTTCCCCTATGGGGGTGTGATAGAATATCTTCTCCTAGGTTTGACTAGCCCCTGGCCCGAATTCCCCTTAGTTCCTGGATTCTGTGGTTCTATTTGTTCTCCATCGCTCCTTGTAACTGGAGGAGTGACTTCTTCCGAGAGTCACTTGGCACCACTTCACAGCAGAGGAACACCAGTATCTTCACTGGCCTAAAATCAAAGAGTGGTTGCAAGGAAAAATCTGACATTCCAACCTTTTCGTTTGTATTTCTGTGGCAGGGAGGCAAGATGACTTCTCTGCCCCAAGCTTGGAACAGCTAAAGGGAAAAACA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003494 REGULATORY REGION Promoter description: KIAA0645 gene product. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.698947368 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 7.912607423 HeLa: 7.560187359 HT1080: 7.800827867 MRC5: 5.135153871 JEG3: 8.561375119 U87: 7.057165596 G402: 4.826535451 HCT116: 6.363054941 CRL1690: 7.204575135 AGS: 8.578846881 Panc1: 4.716717661 HMCB: 8.54434633 MG63: 7.851041482 Snu-182: 4.383338075. Number of positive cell lines: 14. Mean: 176.9084046. Mean(log): 6.892555228. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 9681 DEPDC5 NCBI 2060 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence AGATCACTGAGTCGGAAACGAAGCTCTGTGGCCATGGATCTACTTCGGATAGACTAGGAGGAAATGGATTTCCTCCGTGGGGCGGGAGGCTCTAGTGCTCGAGGGCAGGAAACGCCAGGAGGTGGCCCAAGGAAGAGGCCGCACACGACGCCCCGCCCCCGGCTCGAGCCCCGGATGAGGAAGTGGTGCGGCCACCGAGACGAGACGGAGGCCCGGCGAGAGCGGCGCGGGGGCGCGAGGGCGGGAAGGAGGCGGGGCCCCGGGGCGGAGCCACCGGAGCGGCGCGGGTTCTCAGGTGAGCGCTACACGGTCGGGGCGGGCCTAGTAGGCGCTTCAGGCTTAGGGGCGGAACAGCGCGGGCCGCGCGGGCGTAGGCGGGGTATCTGGAGGAGGCGCAGGGAACCTGGAGAGGGTCCAGCCCTCAGTGCCCCGGCCAGAGGCGGGAAGGGGCTCTAGAGCTTCGGTGAGTGGAGCT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003495 REGULATORY REGION Promoter description: "CDNA FLJ41905 fis, clone PEBLM2006113". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.520912548 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.153719993 HeLa: 1.158402558 HT1080: 0.853140688 MRC5: 0.606383825 JEG3: 0.312066924 U87: 0.755351185 G402: 0.966115254 HCT116: 0.564835718 CRL1690: 0.424781476 AGS: 0.470712829 Panc1: 0.572279142 HMCB: 0.559026962 MG63: 0.389088796 Snu-182: 1.075717726. Number of positive cell lines: 0. Mean: 0.581526306. Mean(log): 0.632973077. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK123899 AK123899 USER DEFINED 2061 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ggcctcgtctctaccgctactattaataataaactagctgggcatagtggcatgtgcctgaaatctcagctactcggaaggctgaggtgggagaattgcttgagtccaggaagtcagctgcagtgagccaagatcgtgccactgcaccccagcctgggtgacagagtgagaccctgtttcaaaaataaaagaaagaaGGGGTGCCCAGGCCACAAAAGGGCATTTTGTGAGATGTGGGCACATTCCTGGCACATCTGTCTCCAGGGAGTTTACTAATTCCTGGGGAATAAGGAATGCCACTCTCTGGTGGAGAGGAAGAGACTCACAGAGAAAAACAGTTTATGAggccgtgtgcggtggctcacgcctgtaatcccagcactttgggaggccgaggcgggaggatcacctgaggtcaggagtttgagaccagcctggccaacatggggaaaccccatctctactaagaatacaaaaattagccaggtgtggtggctcatgcctgtaatcccagctactcgagagg 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003496 REGULATORY REGION This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.529296875 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 1.108801796 HeLa: 0.561781819 HT1080: 1.301165628 MRC5: 1.383799287 JEG3: 0.767617278 U87: 0.569766766 G402: 1.172518215 HCT116: 2.317103675 CRL1690: 1.181482947 AGS: 2.926505444 Panc1: 1.214037828 HMCB: 0.929888682 MG63: 0.625201349 Snu-182: 0.869080941. Number of positive cell lines: 2. Mean: 1.613953922. Mean(log): 1.209196547. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom NM_015372 NM_015372 USER DEFINED 2062 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence cgcccgaatttctgaatgtataggtctaaggcggagttcaagGGGATCCTCCCAGGTCTCAGGAGGTTGTACACTGAACATAGGTTGGTGGTCGCAGTTGTTCTACCACTGTGTGACCTTGACGCAGGGAGAGGAAATATTCATTTACAGAAAACGTAAAATAACGTGGAGAGAGAGTGAGATGGTAACCGGAACTCAGAAATGCAGGTGGTGTGTGACCCACGGTATTTTGCTAGGGTGTGGCTGGGCACGACTCATCCACCGGAGAAGCTGCAGAATCGATTTATGAGGGTCTCAGGAATGCAAAGACACACAGATTCGTCTCACCTAGAAGTCACGTTTCATTTTAATCTCCAAGCAGACAGCGCAGCAGCAAACCTGGGGCTGTGGAGTGGGGCCCCACACCCTCCGCCCACTCTCCCGCCCCCGTCCACGCCTAGACTGCAGGAAAGGGGTCTTCGCACACAAAGCCAGACCCCCAGGCGTGGGAAGATGGAACCAGAACAATTCGA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003497 REGULATORY REGION Promoter description: "solute carrier family 5 (sodium/glucose cotransporter), member 1". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.646365422 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 1.158083197 HeLa: 1.51955166 HT1080: 2.121386779 MRC5: 1.349398463 JEG3: 0.682896137 U87: 1.58526003 G402: 2.222850081 HCT116: 3.371821284 CRL1690: 1.170560581 AGS: 4.055416229 Panc1: 2.788334493 HMCB: 2.839622321 MG63: 1.357149497 Snu-182: 0.92679822. Number of positive cell lines: 4. Mean: 3.930773459. Mean(log): 1.939223498. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 6523 SLC5A1 NCBI 2063 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence GAAGAGTGCTGCACCCATTTTACAAGCGGACAAGCCAAGTCCTTAGAAGGCATGGGACTAGTCCAAGGATGGGTGGCAGGTGATCTGAAGCCTCTAGGCTCCTAGCCCCAGGTGGCCTGTTCCCTCAATGGAGCCACTCCAGCTCTGGCAAGGGCAGGTGTGGTGGCGCTGCTGGTGCCTGCTGTGGGAGTACAGTGGGCCTTTGTGCCAGGCGGGCACCACCCCCTGGCTGGCCCCTCCCCATTCGCAGGACAGCTCTTACCTGCCGGGCCGCCGCCCCAGCCAACAGCTCAGCCGGGTGCTCCTTCCTGGGCTCCACGCCCGGAGCTGCTTCCTGACGGTGCAGCCGCAAGGCATCGCAGGGGCCCCGCGCTACTGCCCTGCTCCCTCAAAGTCCCAGGTCCCCTCCCCTGGTGCTGATCATTAACCAGGAGGCCGTATAAGGAGCTAGCGGCCCTGGCGAGAGGGAAGGACGCAACGCTGCCACCATGGACAGTAGCACCTGGAGC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003498 REGULATORY REGION Promoter description: hypothetical protein LOC150297. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.503636364 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 2.370986483 HeLa: 3.267156962 HT1080: 5.014079932 MRC5: 2.424264871 JEG3: 2.298441794 U87: 3.684310503 G402: 4.067885513 HCT116: 3.708685057 CRL1690: 2.186543523 AGS: 3.405897455 Panc1: 4.520662823 HMCB: 4.199373489 MG63: 4.273613371 Snu-182: 1.263497521. Number of positive cell lines: 11. Mean: 11.73717525. Mean(log): 3.334671378. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC040263 BC040263 USER DEFINED 2064 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CAGTCATCACGCTTTATCGAGAGTGGGACCAGGGCTCTAGGAGTTGCTGTGGTCAAGTTGAAGACAAAAAGTAACACTTGTAAGACAGGAGAGAAGCATTTACTTACAAAGCAGTCCGAAATTTGTGTATAACTACATTTGGTGAGCAAACGAAAGCTGCCAGACTCAGAAAAACAGAGATGCTAATGGAACTGACTTTAGTAACCAGGGTTTTCTATTGAGTTCATTGCCCAGGGTGACTTCCAATAACAACCTCCAACCCCTGCACTTTTCTCAGGACTGGAAAGCTCAGGCAGCCCAGGATGAATAATGCAGTCACCACAGAGGGACAGGGTGGCCACAAGGTGGGCAGCAGCAGGGATGGGCATTGTGAGGCATTTGGTGGGTCTGTGGGGTCGGCCATTGTGAGCCACTAGCCTGACTTGGTTGTTTCCTGGCAACCAGGTGACATAGGAGGTTTTGTGGTTACTAGGCAACGGCCAGGGCCAGCAGCCTTCAGTCGGTAGCTGGCCGTAGAAGGAGGAGGAGCTCCGACTACATTCTGTCCTTG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003499 REGULATORY REGION Promoter description: ret finger protein-like 2. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.646271511 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.262584339 HeLa: 1.638160126 HT1080: 1.288915702 MRC5: 1.031169292 JEG3: 0.264606395 U87: 1.543834129 G402: 1.378289571 HCT116: 1.297363925 CRL1690: 1.062663732 AGS: 1.691652597 Panc1: 1.564910765 HMCB: 1.213081253 MG63: 0.954430916 Snu-182: 0.755420729. Number of positive cell lines: 0. Mean: 1.299694566. Mean(log): 1.139077391. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 10739 RFPL2 NCBI 2065 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence gtaaggagcagtagtgcgtgttgcattgctcatggcgggggagggttgggtgcgttatcccgggcgtcatttcccacagcggcgggggtcagtggaggggcttgttgagggcgctatccatggctgcactggtcgctgaggggcaaggattgggggcgctacctgggacatcagtgccatggtggggaacttgttgggtgtgttatccgaggcatcactccccatggctgggggctggttgggggcgctacccatgggctgcactgcccacagccaggagcgtgtatgggacattatcgggggcggactgccagtggctgggtggggaggcgggttggatgctatgtggggttgcactgcccagcagggagtgagttcggtgcgctatctggggttgcactgccggcggtgggtggcagattgggtgccctatcgctacactgccgcggcgagtaccgggttggcggcgctatcctgggctacaccgccggtggcgggaggcgttttaggggcgctatctggt 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003500 REGULATORY REGION Promoter description: ret finger protein-like 2. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.509846827 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 1.231683069 HeLa: 3.458496248 HT1080: 2.889370626 MRC5: 1.747180907 JEG3: 1.921554557 U87: 2.783065356 G402: 2.141334964 HCT116: 2.350195112 CRL1690: 1.452745678 AGS: 2.423396038 Panc1: 2.729424787 HMCB: 1.669165916 MG63: 2.699344938 Snu-182: 1.393100055. Number of positive cell lines: 8. Mean: 4.094654676. Mean(log): 2.206432732. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 10739 RFPL2 NCBI 2066 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence gcggtagatgactctagcctctggcatgcgcggcaagtggctcctcctccttctcctctaagccgggcacagagcagctacgcaggccgacgcagatgagcctggaagggcaagccacccctcttggcatcctttatatactgagtttaatgcaaatgaagtttctcgactacatagtctgatcggatgagagaaacctctaggcctactctgatcgggctttgttatcttgttctgattggttatcctaagacttgctgtcatccagtcagaacgtgaaaataaagcacaatcagagtagacctagaggtttttctctcatccaatctgaacatgtagtccagaaaccttacttgcataacctcggtctgtggggggaggggttcttgccattccaggcacttctgcgtctgccagcccatctgctccatgcccaggttagaggaggagtcacctg 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003501 REGULATORY REGION Promoter description: "solute carrier family 5 (low affinity glucose cotransporter), member 4". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.514925373 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.117205449 HeLa: 0.628090888 HT1080: 0.258557009 MRC5: 0.885409318 JEG3: 0.305180313 U87: 0.454317484 G402: 0.409038824 HCT116: 0.414075938 CRL1690: 0.904150756 AGS: 0.26894775 Panc1: 0.33095626 HMCB: 0.53068012 MG63: 0.355838124 Snu-182: 0.672252056. Number of positive cell lines: 0. Mean: 0.399413531. Mean(log): 0.466764306. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 6527 SLC5A4 NCBI 2067 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence GAATCCACGAAAGGCATAATTCACTTCACTGTCAAGGGATATAGCTCATTGGTCAGAAACTGTATCTGTTCTCTGAAGGACCATTGCATTCGGTCCCTCCTGGCTGGTTTCTGGTACCTTCTAGTCTGTCCTTCTCCCCTCCTTGTCTGTCTTCATTTCTCTCAAATCCCCCCTCCACCTGGGCAAATCTCTTTAAAGACCCTGTCTTTGCACTCAGAGAACGCCCCATGCTCCACCTCAAATTCTCCCCTCATTTCTGGCCCTGCATCCCTCATTCTCACACTCTACCTAGGCTAGCACTCACTGGTGGAGGGCTGGGGTGCCACAGCTTTGGAGAAGAGGTTTAAAGGTCTCCATATCCAGGAGCTGGCTCTGATATCTCGCCCCACCTGCCTGAGGCTGATCATTAACCCAGAACTTATATAAAGATGGCTCATGCGTGGAATGGGTATAGCACTGCCTGCAGCCATGGCCAGTACGGTTAGCCCCAGCACCATAGCTGAGACCCCAGAGCCACCTCCATTGTCTGACCACAT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003502 REGULATORY REGION Promoter description: developmentally regulated GTP binding protein 1. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.5 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 1.584199094 HeLa: 1.266524277 HT1080: 0.892828451 MRC5: 0.913482044 JEG3: 1.242088597 U87: 0.735522547 G402: 1.000992793 HCT116: 1.003591203 CRL1690: 0.760497216 AGS: 1.036538414 Panc1: 1.153221044 HMCB: 1.101775167 MG63: 1.4591828 Snu-182: 1.15086549. Number of positive cell lines: 0. Mean: 1.161932111. Mean(log): 1.092950653. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK055495 AK055495 USER DEFINED 2068 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TCATCAGTGTTGGGTTGAATGTTGAGCTGAACTATGTTGCCACCTGGGCCACTAAAATGCTTttttctttttctttttctttttttttttttgagatggagtttcgctcttgctgcccaggctggagtgcaatggcatgatctcggctcaccgcaacctccgcctcccgggttcaagcgattctcctgtgtcagcctcctgattagctgggattacaggcaggtaccaccatgccccgctaattttgtatttttagtagagatggggtttctccatgttggtcaggctggtcttgaattcctgacctcaggtgatccgcctgcctcagcctcccagagtgctgggattacaggtgtgagccaccgtgcccggccAACTAAATGCCTTCTTTCCCATAACCCAGACTTTCTGCTTGAATCCCCATGAAAGTCCTGGCTTCAGCCAATAACTTGGGCGAAGGTGCATTGCAAGTGAGGCAACTGGTGTGATCAAAG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003503 REGULATORY REGION Promoter description: developmentally regulated GTP binding protein 1. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.445564516 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.089778949 HeLa: 0.260044186 HT1080: 0.304355632 MRC5: 0.861794328 JEG3: 0.318870345 U87: 0.441353434 G402: 0.805988525 HCT116: 1.089941124 CRL1690: 0.684865815 AGS: 0.583497435 Panc1: 0.163043084 HMCB: 0.446870653 MG63: 0.213089679 Snu-182: 0.897907018. Number of positive cell lines: 0. Mean: 0.457671425. Mean(log): 0.511528586. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK074476 AK074476 USER DEFINED 2069 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TTTCATTGAGCAAGCATTTAGCACTGCCAGAATGTTGGGGAGAGAAGGTTGCTGAAATCCAGTTCATCCTAAGGCCTCAGGATGTTCTGTGAATAGGCTTTGTGTCCATCATTTAGCACCCTCCCCATGGCTTGGTCCAGGGACCCCTGGTCTCCTTGAGGAGAGAATTACCCTACCTTTCCCTTTCTCCTCTGGGCTTAGACTTAGCAGTTCTGGGAGAGGGGTATGTTTGGTATTGGGAATGCTGCCTAGGGTATGGCCACTGTGGAGGTACAGCTAAAGGCTTTCTCCTCATTAACTCTAAGACTTTACTGGTTTGGCTGTCATAGCATGATTTGAATTTCCTGTGCTTTTACATATTCCATGTTTCTTTCCTGACTTTATTACAAGTAAACAGATCCATTGTTCTGTGCCATTTAACTAGTTAGAACACGTTTAGCTGCATTTAGCAGAAAGTGCTAACTTAAGCGGCTGAAATGGAAGGGAACTTGGTCTT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003504 REGULATORY REGION Promoter description: developmentally regulated GTP binding protein 1. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.429400387 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.081653158 HeLa: 0.72785813 HT1080: 0.258331367 MRC5: 1.08066876 JEG3: 0.245109157 U87: 0.893275342 G402: 0.380222058 HCT116: 0.508201416 CRL1690: 1.034720001 AGS: 0.257205058 Panc1: 0.456443595 HMCB: 0.545846738 MG63: 0.628929961 Snu-182: 0.8482066. Number of positive cell lines: 0. Mean: 0.51532116. Mean(log): 0.567619382. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK127132 AK127132 USER DEFINED 2070 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TGGTGTCACCTTGTATGTCGAACTGCATAAAAGATCTGGTAGGCTGGTCAGCTACATGCAGCTCATGTGTCATTGTCAGAATTTGTTTTGGGATGGGCTGAATGAGGAAGGGTATATACGGTGAAGCAGCTACAGAAGGGATCCTTGGGAACTTCATCTTGAGTGTGAAATGGATAAAAATATGACATGCTGCATCTTACTTGATGTTTACTTATGGGAACCCCTTCCAAACTAGATATGGCTTTCAGTCCTTTCAAGTAGTCTTTCCCACATGATACTGGAGAGAGGAAGGACTTTATGTAAGTTAATTGATCACTCCCCGCAAGGCTAACCTATTTTGGGAGATCATgtaattaagtactccgaccaggcagatcagggtttgaaattgcaggtccacctctagttagctgtggagccctgaacaaattacccaacctttatgagcctcagtttcctcatgtaacatggggatagtaatagcacttactttctgcggtggtgattgttagtaatg 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003505 REGULATORY REGION Promoter description: "CDNA FLJ36925 fis, clone BRACE2005169". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.438563327 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.046314501 HeLa: 0.491209088 HT1080: 0.278578493 MRC5: 0.635977852 JEG3: 0.233820299 U87: 0.463411167 G402: 0.346866265 HCT116: 0.392888041 CRL1690: 0.303246673 AGS: 0.195677744 Panc1: 0.135761547 HMCB: 0.326904909 MG63: 0.357494323 Snu-182: 1.002943431. Number of positive cell lines: 0. Mean: 0.311589192. Mean(log): 0.372221024. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK094244 AK094244 USER DEFINED 2071 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TGCTCGTAATCTTAGAAGTCCGCAGAAGGGGGCTTTGGGCACAGGCAGCATTCCCTTCTCTACCACCTCGGCTGTCCCTGGCATCTCTGTAGAAGTTGTCCTTCTCGGAGGCTGCACTGGGTATTTCAGATCTCATCTCCCCCATCCTGAGGCACAGCAAAAGGGTTTTCTGGAGGAAATACAAGGAAAAAAAATATCACATGGTGTCTCCTCAATGGGGACTCACTGGGGACATTTCTCTCTGGCCTCAGTGCCAGAAGAATCCAGGTTTCCTCTGAACACATGGGTTTTGTCTTCTGAACGTTGTGAACCATGTGActttaagactggaagcgagacaaaaatgtcgctatcattatagctccatatagtactagagctctggctcatgcaataaggcaagaaaaaaaagcatagactaggactggaatagaagaaccaaaattacagttaattgtggataacttacatagaaaatttaatagaatcaacaggttaattagtagaaTGGAGAGTGCATACATAGAGG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003506 REGULATORY REGION Promoter description: ret finger protein-like 3. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.545454545 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.122496024 HeLa: 0.419920421 HT1080: 0.458664002 MRC5: 0.986548315 JEG3: 0.222455752 U87: 0.651749811 G402: 0.618916578 HCT116: 0.708242879 CRL1690: 1.053084938 AGS: 0.891045217 Panc1: 0.56861221 HMCB: 0.667463307 MG63: 0.722003213 Snu-182: 0.794547561. Number of positive cell lines: 0. Mean: 0.576740144. Mean(log): 0.634696445. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 10738 RFPL3 NCBI 2072 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence gagatggtgtctcactctgttgcccaggccggagtgcaatggcacaatcttggctcagtgcaacttctgcctcccaggttcaagcgattctcctgccaaagcctcccaagtatctgggattacaggcgtgtgccaccacgcctggctaattcttttgtattttcagtagagatggggtttcacccatcaggctggtctcgaacttttgatgacctcagatgatccacccaccttggcctcccgaagtgctgggattacaggcatgagccatcgtgcccagccTCTCAGCTCCTAATTCTTATGTTCATCAATCAGTCTCTTGCTGGGGTTCCCCTAGGAGGTGGTGAAATGACCCCAGCTCGCTGTTCCTCACATGGGTGCTGCCACGTCACTGGCTCAGGCTCAGCTGCTGGGTCACCAGGAGAATGGACCCTTCCTCCACCTCAGCTCAGAGCACAGTGATGATTCGTGAC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003507 REGULATORY REGION Promoter description: ret finger protein-like 3. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.62992126 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 1.151429836 HeLa: 1.376110135 HT1080: 1.773526249 MRC5: 1.100587627 JEG3: 0.498701655 U87: 0.815822193 G402: 1.060610615 HCT116: 0.855471559 CRL1690: 1.265087333 AGS: 1.056570729 Panc1: 1.461498118 HMCB: 1.365174452 MG63: 1.441705211 Snu-182: 1.167443531. Number of positive cell lines: 0. Mean: 1.301763878. Mean(log): 1.17069566. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 10738 RFPL3 NCBI 2073 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence aatgatgccctggatataacacgtcccgcccaccgcaggcagagtagcacccgatagcgcccccaacccgtgcctgacaagggcaatgcaacacccgatagttcttccaactcgcccgccggccacggccactgcatccccagatagtgcccccagaactccccactgccgctagcagtacagcttgggatagtgctccaacccacccccagccacgggcagcgcacacccgatagcacccccaacccactcccctctgtgggcagtgaggccccagataccacatccaaccagcctcctaacacgggcagtaacgccctggatagggcctccaacccaccccaccacgccacgccacaggcagtacggcctgggatggcgaacttttcccaccaccattttaccattctggctgcgctctagtctccctggcccgcaccaacggcagcagcgaggtgagccacggcaggctccagcctccactgtgctaatgaagttgctcctcctc 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003508 REGULATORY REGION Promoter description: "Clone IMAGE:5272895, mRNA". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.499061914 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 4.575044027 HeLa: 2.891896318 HT1080: 2.968380988 MRC5: 1.402560223 JEG3: 4.406322659 U87: 2.53674797 G402: 2.042405215 HCT116: 2.590623921 CRL1690: 2.613233582 AGS: 3.188027915 Panc1: 2.37205639 HMCB: 2.939852674 MG63: 3.239638252 Snu-182: 1.666418146. Number of positive cell lines: 11. Mean: 7.541512697. Mean(log): 2.816657734. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 10737 RFPL3S NCBI 2074 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence tgagcttgggttttgttgttttttttttaagtaaaacgcctaatcttttattttattttattttattttattttTTTacggagtctcgctctgtcgcccaggctggagtgcagtggcgctatgtcggctcactgcaagctccgcctcccgggttcacgccattctcctgcgtcagcctcccgagtagctgggggctcccgccaccacgcccggctaattttttgtgtttttagtacagacggggtttcaccatgttagccaggatggtctctatctcctgacctcgtgatccacccacctcggcctcccaaagtgctgggattacaggtgtgagccaccactccctgccgtaaaaggcctaatctttaatgaccctcctgtgcgtgtgaaagcactcttgttggtgcagcagaaagcggacctcacaatacacattgtgactttaccctgagacgttgatgatgctcctatcaccatggttatgtgattgggtatatcttgccctcggtcctaactgccactgtctgtgctga 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003509 REGULATORY REGION Promoter description: "Hypothetical protein LOC339666, mRNA (cDNA clone IMAGE:5272406), partial cds". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.573012939 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.265496675 HeLa: 1.650350312 HT1080: 0.909671675 MRC5: 0.941351172 JEG3: 0.475716061 U87: 1.03614205 G402: 1.041270019 HCT116: 0.801698729 CRL1690: 1.123197562 AGS: 1.089250561 Panc1: 0.826487791 HMCB: 0.678968657 MG63: 1.06845802 Snu-182: 1.133692923. Number of positive cell lines: 0. Mean: 0.953878578. Mean(log): 0.931553729. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC041349 BC041349 USER DEFINED 2075 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TTCTTTTAGTATCAGCAACTTGGGCCATGGCCCAGGGCGTGGCCATAGATACTTCTAGACTGACACTCACTAGGCTCTCAGGCCGACACCACTCACATGACTTCTACTGAGGGAATGCAGTCTGGCGAGAGAGCAGCAGGAGACACTGTGGATCTCAGGGTCTGTGCAGTGGGCAGCCACAACTGTGCCAACCCCCTCCTACCCCACAAATTCCGCAGGGCTGGGTGATGGAGCCTGCACTCACTGAGGCTGACCTGGAAGCTGTGCCCTCCCTGGGTGTGGTTCCAGCACCCACTTCTTCCCAGGTCTGGCCTGTCGGACTTCCCCTGTCCACCAGCCCCTAGGACTTGAATAAATACATGGGGTAAAGTAGAGGCAGGCAATGTGGGGACACATTGGCATCTGTAACTCCTCCTCTGTGAGGTCAGTGGAAGGGATAAGAGAGGCCTGGAGCAGCCCACTCCAGCTCTGGACCTCAGAAGGGCTGTGTCCACCATGGCTCCTGTCCTCCTGCTGCTCCTCTCTCACTTCCCAGGTAAGG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003510 REGULATORY REGION This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.594059406 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 2.35843741 HeLa: 1.011325049 HT1080: 2.618786376 MRC5: 1.31904034 JEG3: 0.910833222 U87: 1.456397071 G402: 1.392557937 HCT116: 1.640169068 CRL1690: 1.17199185 AGS: 1.17165472 Panc1: 2.637952232 HMCB: 1.757334498 MG63: 1.427181371 Snu-182: 1.012860512. Number of positive cell lines: 2. Mean: 2.21187858. Mean(log): 1.563322975. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AL110165 AL110165 USER DEFINED 2076 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence GCACCTTAGGTCCCCAGTAAAATATAGGGGAGGCTATGGCCAGGGCCGACCCCCAAGAGAACCATTCCCAGCACAGGGGTTTCCTATCTCTGCCTGTCCTCCATGCCACATCTGCCTCTCCCAACCCAAGCACCAAGTGGCCCAGAGCTGGAGTTTTGATGGGCAACCTGCTCACACATCTGCCTGGAGCTGCAGTTGTGAGTGCCCAGGTGCTCAGCACTGTGTGCCAGGGCCTTTGGGAAGAGAATGTCAGTAGGAAGCCGGGGCCCGCAAGGGTCTGTATAGCCCTGCTGCATGGCCAGGTCTGCCCCTATCAAGACAGCACAGATGGCTGGGGCTGGAGTGGGGCTGTCCTCTACACAGGAAGCAACAAGCCAGGGGCCCAGAACCACAATAAAAAGCCCCGCAAGggccaggcgcggtggctcacgcctgtaatcccagcactttgggaggctgaggcgggcgaatcacgaggtcaggagatcaagaccatcctggctaa 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003511 REGULATORY REGION Promoter description: hypothetical protein HSPC117. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.453358209 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 9.488552084 HeLa: 8.728497537 HT1080: 9.340221071 MRC5: 7.441315106 JEG3: 8.179137967 U87: 9.911413556 G402: 5.684594804 HCT116: 6.987834821 CRL1690: 9.023240058 AGS: 9.015807029 Panc1: 5.377281549 HMCB: 10.15566564 MG63: 7.747052785 Snu-182: 4.860657266. Number of positive cell lines: 14. Mean: 417.556052. Mean(log): 7.995805091. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AF161466 AF161466 USER DEFINED 2077 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence GATAAGCTGCCATGCTTCATTCTTTGGGATGCTCCTTTCTGACCAAAAAAGTTATTTGGTGTATATCCAGATTCATTCTGAAACATAAATGTTCAGCTATGGTATTTACTCAAACAGGTTTTTCTTTCTCAGCTGCTGGCGTTATCTTTTTCCCCTCCCAGCTGAGGGTGTAAACTCCAAGCCAATGCACCGAACCTGACCCAGACTCAAGGTGTTTTCATAAGCTGCTGAAAAGCATTTCCAAAACAAAAGATAACTAGATTATACTTTAAACTTCTGGATTTCGCTTAGCTGTAGTTTAGAGGAAATCGACTAATAAAGATCCTAAAGTTATACACTACAGGACAGTACAACTTAACCAGAGGAAAGACATTGGCCTGAAGAATTTTGAGCCTCGGCGCTTGCCGTTGCTCATCTGCTGCGGCGCTGGTCGCGCCTGCGCTTTGGTTCTTGGAAGGCGGTGCTCTGAGAAGCCGGACTACGCGGCAGCGGCTCTTCAAAGCGGAGCCGGGAGTTTTTGCTACAGTTTTCGCCAC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003512 REGULATORY REGION Promoter description: bactericidal/permeability-increasing protein-like 2. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.432926829 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 1.255099713 HeLa: 1.412965396 HT1080: 0.490930533 MRC5: 0.904610308 JEG3: 1.148283998 U87: 0.716888686 G402: 0.959222118 HCT116: 0.921030459 CRL1690: 0.673829843 AGS: 0.777030467 Panc1: 0.623067365 HMCB: 0.989166677 MG63: 0.666282679 Snu-182: 1.112757773. Number of positive cell lines: 0. Mean: 0.900612886. Mean(log): 0.903654715. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 254240 BPIL2 NCBI 2078 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TGAGGGAAGTTTTCACAGAGAGGGACATGGAGCTGGCCCTGAAGGATGCATAttcactactagtctgtgaaaaacataggtcaggggccatgtgtaggtcaacactacacccttagcacctagaacacatgctggtgtgttcaataaatgattgCtgaatgaatggatggatgggtgggagagcgcatggatggatggatggatggatggatggatggatggatggacggatggatggttggatggatggatggatggatggatgaatggatggattggatggatgTATTGAGTTCTGGAAGTAAACAGTAAAAATGAGAAAATCTAGAAATGTTGGATTTAATTGACCAAAGAGAAAGTCAAGAATAATAAAGGAACCTTAACTGTTGGTTAATTTCAGATGTGTACAAAGACAATCCCAGTCCTCTGGGGATGTTTCCTCCTGTGGAATCTCTATGTCTCATCCTCTCAGACCATTTACCCTGGAATCAA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003513 REGULATORY REGION Promoter description: bactericidal/permeability-increasing protein-like 2. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.43071161 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.890057551 HeLa: 2.215322918 HT1080: 2.35853875 MRC5: 0.96928399 JEG3: 3.66762625 U87: 5.710325091 G402: 0.832694388 HCT116: 2.822709488 CRL1690: 1.383796193 AGS: 2.225432754 Panc1: 1.026190194 HMCB: 0.453482059 MG63: 1.161495869 Snu-182: 1.219788393. Number of positive cell lines: 4. Mean: 6.340187469. Mean(log): 1.924053135. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC062656 BC062656 USER DEFINED 2079 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ACTGAGAGATGCCAACTGAGGTCCTACCCTGAGTGATAAGGTAACTAGGTCAGCCCGATTGTCAAGCCTCATGCTTTCAGACTGAATCTGATGATCCACCACAAGTCCCAAAGGTATTCTGGGCAGTAGTAGAGCCATCCACCGCAGGCACCCTGACCAGAAGGAACCAGCTTATGATTCCAGACAGGAAAATTCTTCCTCTTCCAATGCAGTTTAACACCGTTTTCAATCATTTTGGTAAAGTAGCCATCACAATTTCACAAGTGgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtTTTGCAGGAAGATAATTATTGCATAGGTGGCACTGTCTGTTTATCTAGGTAGATACTGTAGTGCTCATTCATGCCATTGGGTAATTGTAGTGAAGCAATTATGTATCACATTTTGAAAGAGGCATTAAAAAAATTCACCACTGAGATGAGTCAGACTTAATTATCTTGGCTTTTTAGCAGCTGAGTTTAAGGCGCAAGGTGGAGAACACATCAGCTTCAAAGGCAGAGAGAA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003514 REGULATORY REGION Promoter description: F-box only protein 7. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.612244898 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 3.407662363 HeLa: 2.870178295 HT1080: 3.308184177 MRC5: 2.339777355 JEG3: 1.195396641 U87: 1.757297595 G402: 3.16593745 HCT116: 2.558206311 CRL1690: 1.924570078 AGS: 2.665858855 Panc1: 3.138486367 HMCB: 2.916087654 MG63: 1.912133756 Snu-182: 1.236952588. Number of positive cell lines: 9. Mean: 5.145985463. Mean(log): 2.456909249. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 25793 FBXO7 NCBI 2080 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence caactagctgggactacaggcaggcgccaccacacctaattttttgtattttttgtagagatgggggggggggtttcaccatgttgcccaggctggtctcgaactcctgggctcaaacgatccacccgcctcggcctcccaaagtgctgggattacaggcgtgagccaccgcgcccggccAACCTAAGGATTAACCTAAGGCTTCTCAGAGCAGATGCCGCTGGAACTGAGGGCCACGGAAGAAAGGGGGTGACACTTGGTCCTGGGGAGTGGCGACTGTATTGTCTGTCTGCAGCATCCCTATCAGCGCTACCGTTGTTCCACGCACACAGGGAGTAAGTACTGGGAGTCCCAGCCACCGCCGCGGAAAATCTGGGATGCCAGCGAGCGGCCGCATCTCGGCGCCTGCGCACTGTGCCCGCGCTCTCAGGCAGCGCCGTTGCGCGCGGAGTCATCGATCGGCCGACCCCGAGAGGCCCGGTTCCTTTAG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003515 REGULATORY REGION Promoter description: eukaryotic translation initiation factor 4E nuclear import factor 1. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.459558824 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 3.673909392 HeLa: 3.168399652 HT1080: 2.959286424 MRC5: 1.552595097 JEG3: 3.6024494 U87: 1.706287949 G402: 2.946430431 HCT116: 3.664340321 CRL1690: 1.236711354 AGS: 2.614373985 Panc1: 2.706721302 HMCB: 2.473607724 MG63: 3.967464792 Snu-182: 1.186191628. Number of positive cell lines: 11. Mean: 6.624478978. Mean(log): 2.675626389. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 56478 EIF4ENIF1 NCBI 2081 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TCTGGATAACCCTACAACTCCCAAGTTCCTGTACCTATTCTGTCTACCTGAACTGTTGTTCTCTAGCTTCTTCTTGATCGCACCCAATGGAATGCAGCTTCTTCCCCAGGAAGCATCCCTGCAGTGCCTTGTTATTTCTTCTAACCCCTCCATTTTCCCATTGTACTTTGTTGGTGCCTAATATCTACATGCCTTGGTTTGCTCTAGGTGATtgtctcccccgctagactgagagctcttacaagactgggactgtgtttcattttccttttgtcttccctcagagcttagcatgtgcttTTGTGTATGTTAGGCCTAAATGCTTGGGAAATTGAATTGGATAAGGGAAAGGGGATGTTAAAACTTCTAGGCTGGTCTTGAGTATTATATGGTTTTAAGACTTGAAGTTAAGCAGATTGGGGTTCATGCTGATAATTGGTTTGTTCACAGGCAACAGCGAGTGACCAAGTCACCAGCACCCGTGCATCGAGGGAATTCCTCTTCCCCTGCCCCTGCTGCCTCCATCACAAGCATGGTCAGTGAC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003516 REGULATORY REGION Promoter description: eukaryotic translation initiation factor 4E nuclear import factor 1. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.387308534 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.875567858 HeLa: 1.373672858 HT1080: 0.355280004 MRC5: 0.984995729 JEG3: 0.887195339 U87: 0.714386651 G402: 0.65273188 HCT116: 1.025881808 CRL1690: 1.09033149 AGS: 1.363811209 Panc1: 0.510293652 HMCB: 0.742883268 MG63: 1.041443208 Snu-182: 1.26721014. Number of positive cell lines: 0. Mean: 0.93208891. Mean(log): 0.920406078. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 486366 LOC486366 NCBI 2082 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence cagagcgagactctgtctcaaaaaaaaaaaaaaaaaagtaataaaaaaTAAAAAAGGAAAGTAAGTAGATGGTTATACTCAAGTTTGGGTTATTCAGAAATTACCCAGGATGGAGGAAGAAAAAGGTGTTCAAATTCCTAGGTTCTGAGAGTATTTATCTTCAGGTCACGAGCATGAAAGGAAGTTTCAAAGTAAGTGACCCTTTCATAAGATTTAAACCTTCTTGTCCTTTTTCATCTAGAAACTATTAGTTTTTATTGTCTTTTTCTTCAGATGATAGAAGATGTTTTGGGAGAAGGGTCAGTCTCTGCCAGTCGGTTCAGTAGGTGGTTCTCTAACCCGAGCAGATCAGGAAGCCGATCCAGCAGTCTTGGGTCAACACCACATGAAGAGCTAGAGAGACTTGCAGGTAAAATGGCTTCAGATTCTGCCCTTGAAGGTAAACCTGGGTTTTTCC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003517 REGULATORY REGION Promoter description: eukaryotic translation initiation factor 4E nuclear import factor 1. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.446 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.265342438 HeLa: 1.066562758 HT1080: 0.838071542 MRC5: 1.19248212 JEG3: 0.454169115 U87: 1.173663879 G402: 0.998697883 HCT116: 1.200644159 CRL1690: 0.755651382 AGS: 0.610350843 Panc1: 0.976949747 HMCB: 0.717811355 MG63: 1.180738294 Snu-182: 1.028455781. Number of positive cell lines: 0. Mean: 0.887621456. Mean(log): 0.889970807. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK130061 AK130061 USER DEFINED 2083 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence cagcctggagaacatagacctgtcccaaaaaaaaaaaaaaaaGTAACCACTACTGCTTTAAGAGTGGAGGATTTGAATTTTGCCCTGTATGTGATACCCATTTTGGAACAGCTCGTTTAAAAAATAATAAAGTTgccgggtgcggtggctcatgcctgtaatcccagtactttgggaggccgaggcgggcagatcacgaggtcaggagatcgagaccatcctggccaacatggtgaaaccccgtctctactgaaaaaaaaaaaaaattagctgggcgtggtggcatgtgcctgtagtcccagttactcaggaggctgaggcaggagaattgcttgaaccctggaggcagaggttgcagtgagccaagatcgtgccattgcactctagcctggtgacagagcaagactctgtctcaaaaaataaaataataaaGCTTAAATTTCCTGAAATATGAAACTCTGAAATATAACAATTTTGGCCAAACCTGCATGTTGTTTACT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003518 REGULATORY REGION Promoter description: "Clone IMAGE:4818531, mRNA". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.481262327 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.379549663 HeLa: 1.082157113 HT1080: 0.820509927 MRC5: 1.063814374 JEG3: 0.534380036 U87: 1.903869586 G402: 1.206738234 HCT116: 1.125531434 CRL1690: 0.862211656 AGS: 0.752349837 Panc1: 2.592528931 HMCB: 1.152318134 MG63: 1.109869829 Snu-182: 0.923919806. Number of positive cell lines: 2. Mean: 1.340514496. Mean(log): 1.107839183. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK123891 AK123891 USER DEFINED 2084 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence GAGGGAGGTAAAAATGGAAGTGGCTTTGGCCTGGAGCAGCTTCTAGTTATGCCCAAGCAATGTAGATTGTTTGGTAATCAGCCAAGATCCATCCAGGTTCCCAGGAGCATAAAAGCAATCATCTCCTTTTTGGTCCTTCAAAACCAAACTGGAGTGGTGACGTCAGGGCCAGAGACCCTCTCCTTCTGTGGGCATTGGATCACTTAGAACTCTCAACCTCAGAAAAGCCTGCCTTCAAGCTGGCTTTTGACGGGCTATTGGCTGGAGACTGGGTCAGTATTGAAAGTGCTAGCTGTGCACCTGGCTGCCAGAAAGCCACTTGGCCTTTAGGACAGTCCTCTTCACATTGCCCTCTTCCCTCACTCATGATCAGGTCTGGATTTAAGAGCAAGAGACCCCAGGATAATTCAGAAGTCCTCTCTCTCCTCCTGTTCAAGACTCTTGGTCTGGGATTCAATAATAAGTAGCAGACCTGACATAAGAAAGATCAGATAGGTCCAATTGCCA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003519 REGULATORY REGION Promoter description: "Clone IMAGE:4818531, mRNA". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.512295082 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.301635954 HeLa: 1.482634327 HT1080: Bad Txfn MRC5: 0.915261229 JEG3: 0.703129244 U87: Bad Txfn G402: Bad Txfn HCT116: 0.837409612 CRL1690: 3.128384408 AGS: 0.620371193 Panc1: 0.664562293 HMCB: 1.061488984 MG63: 0.893040555 Snu-182: 0.741162873. Number of positive cell lines: 1. Mean: 1.437319183. Mean(log): 1.031734606. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom BC042456 BC042456 USER DEFINED 2085 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ggtggaatgtcatcagttaaggcagggcagggtcttttcacttcttttgtgattcttcagttacttcaggccatctgggcgtatacgtgcaagtcacaggggatgcgatggcttggcttgggctcagaggcctgacaGCCCCCAAGAAGGTGAGGTGACTACAGGGCTGTGAGCTGTAGGGGAGATGCCATTGTCAGCATCGGTCAGGGAGGTTGGAGTGAGCAGACCAGGACAACTCCACAGCTTAAGCAGCAAAGGTCTGGGACCAAGGAAAGGAAGCACACAGACTGTGCTTCACACAACAAACACAGCAGAGTTCCAAACAGCACAGCCTCAGCTCGAACCAGCCCAGGAGCACACAGTGTCCTTTCAGGTTCTGCCCCTTCCAGCCCCTGAGGGCAGACTAATCTCTTATGCTTTATTCAACTTTGTAAAACACTGGTGGCTCATTTTATGTGTTTTGAATTGGTGAAAGGATGCAGGTTAGT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003520 REGULATORY REGION Promoter description: synapsin III. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.464052288 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 2.108763543 HeLa: 0.696833342 HT1080: 1.602000032 MRC5: 1.114507057 JEG3: 2.126402269 U87: 0.804257608 G402: 2.338078135 HCT116: 1.391139917 CRL1690: 0.75310285 AGS: 1.462270254 Panc1: 1.345777182 HMCB: 1.351534041 MG63: 1.847282957 Snu-182: 1.234262395. Number of positive cell lines: 1. Mean: 1.886559579. Mean(log): 1.44115797. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 8224 SYN3 NCBI 2086 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence tttgtgcatgaagctttttctgtaacttagaatctttctttgcgatataattccagaaaatggaaattgtaggttaaaaagctatcctcttaatacatgttgccaaattcctttccagaaggatgtcctaatttacattaccacctgcagtgGGGCAGGAAAGCGCTGTATCTGTTTGCTCTTAAGGGGGTGGAGGTCGTTTCCACTTATGTATTTGTTGGCTTATTTCCAGCAGGTAAATAAAGGCAGCTAAAGCTGACTGCTGGTTGCGCAAAATCCCCCTGGCTCTTCTGGCTAAAGTCCTACCACTCCCTGTACCTGGCAGCAGCCTGTCTTCTGGGCCTCACCTACACACGTCTGGGTAGGAGCCAGTCATCTCCATCCATCCACAGCCATGAATTTCCTCCGGCGACGTCTCTCTGACAGCAGCTTCATGGCCAACCTGCCTAATGGCTATAT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003521 REGULATORY REGION Promoter description: "tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory)". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.46460177 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.423731861 HeLa: 1.625590551 HT1080: 0.897152689 MRC5: 1.106604286 JEG3: 0.753808049 U87: 0.729487472 G402: 0.944351109 HCT116: 0.759748383 CRL1690: 1.004715082 AGS: 0.546207398 Panc1: 0.753514492 HMCB: 0.918237929 MG63: 0.856929957 Snu-182: 1.020522743. Number of positive cell lines: 0. Mean: 0.877641137. Mean(log): 0.881471571. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 7078 TIMP3 NCBI 2087 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence gggagtgatacttgtgcttgcttttcctacccacaaagattattgtgagagctataatacggtgagataCAGAATCCTGCTTTTAAAAATACAAAGCAGAATCAAGATGTCAATAATAAGGATAGTAATTGTGTTAGTTATCTGCAATCATCTATTATAGCTAGTCGTCTAGGATCCTGGATCGTTCTCCTGGTTTTACTACAGTTTTGGATCAGCTCACCCCCAAATCCCTTGCTGAAGGGTGGAGCTCTGTCAGCCATGGGCAGGGAACCACTTCCTCTTGCCTTTctactttctgtctttcaaacatgcccagggtctttgcacttgctgttccccctgcctggtacctctctcctgtggcttgccccagagctgatccttgtctttgtccacttctcagcgaggatggcacttcagggagcccttcccttactatcgcagagagagca 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003522 REGULATORY REGION Promoter description: "tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory)". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.457142857 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.115456735 HeLa: 0.436494485 HT1080: 0.415446698 MRC5: 1.062436871 JEG3: 0.345152803 U87: 0.552272054 G402: 0.78651923 HCT116: 0.526719546 CRL1690: 0.850257607 AGS: 0.450861552 Panc1: 0.345927389 HMCB: 0.440939307 MG63: 0.453539822 Snu-182: 0.926905798. Number of positive cell lines: 0. Mean: 0.487839911. Mean(log): 0.55063785. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom AK098517 AK098517 USER DEFINED 2088 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence TCTCTTCCCTATCATGGGTCATCTGACCCCTGTCCGTCTCCTTGTCCCTGCTTCATGTTTGGGGGCCTTTCTTTAACTGCCTTCCTGGCTTAGCTCAGATGGCAGATGAGAGTGTAGTCAAGGGCCTGGGCACAGGAGGGAGAGCTGCAGAGTGTCCTGCCTGCCTTGGCTGGAGGGACACCTCTCCTGGGTGTGGAGACAGCTTGGTTCCCTTTCCCTAGCTCCCTGGTGGGTGAATGCCACCTCCTGAGATCCTCACCTCTTGGAATTAAAATTGTTGGTCACTGGGGAAAGCCTGAGTTTGCAACCAGTTGTAGGGTTTCTGTTGTGtttttttttttttttttgaaataaaactataatataaattctcctattaaataaaattattttaaGTTTTAGTGTCAAAAGTGAGATGCTGAGAGTAGGTGATAATGTATATTTTACAGAGTGGGGGTTGGCAGGATGGTGACATTGAACATGATTGCTC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003523 REGULATORY REGION Promoter description: "tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory)". This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.462890625 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.085757787 HeLa: 0.635618745 HT1080: 0.557515568 MRC5: 0.596400237 JEG3: 0.275584266 U87: 0.606023104 G402: 0.259266273 HCT116: 0.425923083 CRL1690: 0.834692332 AGS: 0.34104929 Panc1: 0.229655569 HMCB: 0.415657163 MG63: 0.324503457 Snu-182: 0.955849999. Number of positive cell lines: 0. Mean: 0.401423949. Mean(log): 0.467392634. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom X77690 X77690 USER DEFINED 2089 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence ACCCTACAACTGGTTGCAAACTCAGGCTTTCCCCAGTGACCAACAATTTTAATTCCAAGAGGTGAGGATCTCAGGAGGTGGCATTCACCCACCAGGGAGCTAGGGAAAGGGAACCAAGCTGTCTCCACACCCAGGAGAGGTGTCCCTCCAGCCAAGGCAGGCAGGACACTCTGCAGCTCTCCCTCCTGTGCCCAGGCCCTTGACTACACTCTCATCTGCCATCTGAGCTAAGCCAGGAAGGCAGTTAAAGAAAGGCCCCCAAACATGAAGCAGGGACAAGGAGACGGACAGGGGTCAGATGACCCATGATAGGGAAGAGAGGGTGCTGACGGTGTTCAGAATTTCAAATTTTAATTAAAATGAAAAAAAAATGTCAACTTGGAATGTCATGATTTTCTTCAAACAAGCAACGACAACAAAATAGAAGAGATTAAACTATTGGCATATTTAACAGCATTGAACAGAATTCTGTGTCCTGTAAAAAAATTAGCTTATGTCCCCATGTGGGTATA 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003524 REGULATORY REGION Promoter description: KIAA0542 gene product. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.478346457 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 3.278285851 HeLa: 1.897467641 HT1080: 2.158191749 MRC5: 1.197457856 JEG3: 2.799142411 U87: 1.82329496 G402: 2.427503713 HCT116: 2.742467433 CRL1690: 1.087531144 AGS: 2.344677805 Panc1: 2.04971202 HMCB: 1.923154837 MG63: 3.105266116 Snu-182: 1.106554944. Number of positive cell lines: 5. Mean: 3.903685059. Mean(log): 2.138622034. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 9814 SFI1 NCBI 2090 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence aggctggtctcaaactcctaacctcaggtgatctgccctcctcggcctcccaaagtgctgggattacaggcgagagccactgcaccAGCCATCTGCTTTCTGCTTGTTGATTTTATTCTTCTTTTTTTTAATCCAGGAAAAAATTACTTTTGAAAGCAGAATGTCCCTCTTAAAGACCCTTTTACCCCACGGTCCCATAGCTTATCATCCTGCTAGGGGATTGCCACTTCCTTGTTTCTAATTTCAGCCTTTCCAGCGTGTGTGCCTTTCTCTTTTCCCTCTCCACCTGTACTTCACCCTGTTTTCCTGCCTCTCCTTTGACTGTTGCCTCTTCTCTGGTTTTCAGGCTTGGTCACAGTGGCGGGAACAGCTCCTGTATGTCCAGAAGGAGAAACAAAAGGTTGTCTCTGCAGTGAAACATCATCAGCACTGGCAAAAACGGAGATTTCTAAAGGCCTGGCTTGAATACCTGCAAGTCCGCAGAGTGAAGAGACAGCAGAATGGTGAG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003525 REGULATORY REGION Promoter description: KIAA0542 gene product. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.476953908 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.600803887 HeLa: 0.770610383 HT1080: 0.984816869 MRC5: 1.066006694 JEG3: 0.736039133 U87: 0.993895227 G402: 0.830062856 HCT116: 0.926685703 CRL1690: 0.205734825 AGS: 0.804836295 Panc1: 1.085153082 HMCB: 1.154037272 MG63: 0.585314417 Snu-182: 1.092694065. Number of positive cell lines: 0. Mean: 0.822237733. Mean(log): 0.845477908. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 9814 SFI1 NCBI 2091 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence GAGGAGAACAGGCAGCATAGAAAGTGTTAACTCAGTTTTATGAGCTGATTTGGCTCAAAATTTTGTGTTCTTTCAGATCCTAGGCTGTTCTTATTTGAACTTACTGCATCTAAAATTCCTGATCTAACCATTTACAGGAGTCCTACGTCCTACTGAGTGTAAAACATGTTTAAACTCACATTAATTGAGCTTTTACCGCAAATCAAGCACTTACCTCATCAAATCATCACAGAACCCCTAAGAAGCACGTATTTATAGATGAGGCCAGAGAGGTTAATTTACACTCACACAGATGATGTATAAAATGGAGGCAAAGCAGGAAGCCACCCCCAACTCAGACCCCAGCCCACGGTAGCTGCTTTCTCCTCTGTCTGCAGTGCCTGGCCCTGCGGGGAGCGGAGCGGCAGAAGCTGATGCGAGCAGACCTGCACCACCAGCACAGCGTGCTGCACAGGGCGCTGCAGGCATGGGTGGTAGGAACTGCTGCTTCCCTCCTGAT 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003526 REGULATORY REGION Promoter description: KIAA0542 gene product. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.595833333 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 0.526084182 HeLa: 1.692022303 HT1080: Bad Txfn MRC5: 0.711656948 JEG3: 0.377364754 U87: 1.132880516 G402: Bad Txfn HCT116: 1.05496243 CRL1690: Bad Txfn AGS: 0.668657255 Panc1: 0.9460813 HMCB: 0.607912927 MG63: Bad Txfn Snu-182: 1.146342372. Number of positive cell lines: 0. Mean: 0.913218292. Mean(log): 0.886396499. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 9814 SFI1 NCBI 2092 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence AGGAAAGTGACGTTTGAGGGTCCCCTTCTCAACCGCATTGCTGCTGGGGCTGGGGATGGCACCCTTGAGACCAAGAGGCCACAGGCTTCTCGGCCTCTGGGAGCTCTGGGCCGCCTGGCTGCTGAGGAGCCCCACGCCCTGGAGCTGTGAGTAGCCTGTGCTCACCTTGTCCTCGCTTCCACCCTGGGCAAAAGGTTGGATGGCATAGCAGGGAGGAAAACAGCCCTGACGGGATGGGACGGGCTGGTCACGGCCTTGTCACAGCTGAGCTGCTGGGAACCCCCTCTTCTCCAGCCAGATCCCATCCCTCCCACGGCAAGAGGGAGAGAATGGAGTGGGATTTCCAAACCCTCTCTCCTTTGCCTGCCAAAGCTCAGGAAATAGGTGTCCCCTCCTCTGCAACACCTTCCTACCCTCTCTCCCGTCCTGCTGACACGATCTTTTCCGGAGTCATACACGTAGTTGACAAAGGGAACAAGC 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003527 REGULATORY REGION Promoter description: KIAA0542 gene product. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.504621072 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 6.50893058 HeLa: 5.142151259 HT1080: 6.902732004 MRC5: 5.932806231 JEG3: 5.495787436 U87: 5.953809603 G402: 5.075852381 HCT116: 4.984777935 CRL1690: 4.120262287 AGS: 7.382522688 Panc1: 4.662636992 HMCB: 6.95417112 MG63: 5.914148147 Snu-182: 3.860670352. Number of positive cell lines: 14. Mean: 62.43103819. Mean(log): 5.63508993. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 9814 SFI1 NCBI 2093 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence GCTTTTAGTCTCTGCACCAGGAATCTCACGTGCTTTCAAATGTTTTACAAAGCACGTAAAAAAGTATTTGAAAAGTCCCACTTACCCCTCCCACTCCTATTTTTAAGATTATTAGGATCGGCCCAAATTTAAAAATTTAACAAAAAGAGTGCTTATTAATTACATTTTAAAATGAAGGGTTACAAAAAGAGATGAGCCTGGCATTTCTAATTCGGGGGCCTTGGGACCTCTCCCCTCCAAGTGCAAGTTGTAGCAACCTGCCGGGTCCACGCATGGGCGGGTCATACTCCACGGGTTCCGGTTTCCACTCCCTGTGAACCAAAAGCCAGAGAGGCCCACGCACGAGTCCGGAAGTGAGGGAGGGAGGACTTTCGTACGCAGCCGCCTCCCAGCTGGAACCTCATCTTTAGTGCTCGGCCGCGGGCGGCGTAACTCGGGGTTCCGCCTCGGAATACCTCCCACTTCTCTTGTCTAAGAGGAGCAGTAGCAAGCTGAGCTCAGAGCGAAGCTGGCGAGCCAAGGAGATAAAGAACCCTCGGTG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003528 REGULATORY REGION Promoter description: phosphatidylserine decarboxylase. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the primary publication. Information on each cell type's results and the number of positive cell lines is available in the evidence comments. GC Content: 0.698818898 Promoter is soft-masked. 1-Nov-2005 smontgom OREGDS00001 1-Nov-2005 Cell lines tested and results, HepG2: 6.760279418 HeLa: 4.732936983 HT1080: 5.176227049 MRC5: 5.016988583 JEG3: 5.955389142 U87: 3.517595899 G402: 4.27937282 HCT116: 5.22709305 CRL1690: 2.491549769 AGS: 6.118269419 Panc1: 3.878810075 HMCB: 4.98550229 MG63: 5.111421951 Snu-182: 1.753312968. Number of positive cell lines: 14. Mean: 34.23814782. Mean(log): 4.643196387. 1-Nov-2005 OREGEC00001 OREGES00004 OREGET00002 smontgom 23761 PISD NCBI 2094 POSITIVE OUTCOME 12566409 0 sequence_with_flank EMPTY 0 false 0 sequence CTGAGTCTGCCTAGTGTTGGGTCGCGGGTGGTGGAGGGGAGGCAGCTGCTTTGGGAGGCCAGCCACGGGCTGCAGACAGGCGGCTCACAGACCAGCGGACAGACTGAGGACAGACAGGAGGCATCCCTTGGGAGCAGCCGGGCCCACCTTGCTGGTTGAGTGGGGTCCTCCCGTGACAGTGACCAAGCAGAGCTGGTGTCTGCTGCCCTTCCCCTTCTCCCTGGCCTTGGCCCTTCCTCTTAAAGGGGCCCTCGGGTTGGGCGGACGGCCCAGCAGGACTGGGGCTCAGAGGGGGCGGCAGCTTTAAGGGTGGCTGGGGTCGGCCTCCTGCCCCCGCCCCTGGTAGTCTGAGTGGCTGGAGCCCGAGCCCCGCCCACTCGCCCCAAGGCTTCCCGGCTCCGGGAGCGCCCCTAGGGAGTCGGAGCCCGGAAGCTGGAGCCACCTGCGGGTGAGTGAGCGGAGCCGGCGCCCCGGCCCTGCCGGGAGCCCCAGGTGACTTCTCAGGGAG 0 false 0 sequence_with_flank EMPTY 0 false Homo sapiens OREG0003529 REGULATORY REGION Promoter description: phosphatidylserine decarboxylase. This promoter was annotated from a supplemental file from Richard Myer's lab at Stanford. It has been tested in an increased number of cell types compared to the pr