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Other Resources

Experimental Resources for Regulatory Annotation

Transcription Factor Binding Sites

TRANSFAC Eukaryotic transcription factors, their genomic binding sites and DNA-binding profiles
Drosophila DNase I Footprint Database DNase I footprints for the fruitfly D. melanogaster
Transcription Regulatory Regions Database (TRRD) Structural and functional organization of transcription regulatory regions of eukaryotic genes.
Transcriptional Regulatory Element Database (TRED) Curated repository for both cis- and trans- regulatory elements in mammals (promoters and transcription factor binding sites)
Riken Transcription Factor Database (TFdb) Database containing mouse transcription factor genes and their related genes. It is intended to select transcription factor genes nonredundantly from the entire Mouse genome.
plantCARE Cis-acting regulatory element database for plants
Arabidopsis thaliana Promoter Binding Element Database (AtProbe) Arabidopsis thaliana promoter binding element database
The Arabidopsis cis-regulatory element database (AtcisDB) a searchable relational database, which includes many different datatypes, such as transcription factor binding site information, promoter sequence and related annotations
Regulatory Regions
Hematopoiesis Promoter Database (HemoPDB) Experimentally defined regulatory information, including TFs, cis-regulatory elements, their target gene promoters and corresponding annotations for transcriptional regulation in hematopoiesis
MPromDb Database for gene promoters with experimentally supported annotation of transcription start sites (TSS), cis-regulatory elements, CpG islands and ChIP-chip experimental results with intuitively visualized presentation
Mammalian Promoter Database Collection of promoter databases for human, mouse and rat.
Osteo - Promoter Database (OPD) Database that analyzes promoters of genes which differentiate along with the osteogenic pathway
Orthologous Mammalian Gene Promoter datababse (OMGProm) an integrated resource of mammalian gene promoters
Arabidopsis transcription factor database (AtTFDB) public Arabidopsis transcription factor database
Eukaryotic Promoter Database (EPD) an annotated non-redundant collection of eukaryotic POL II promoters, for which the transcription start site has been determined experimentally
PlantProm DB an annotated, non-redundant collection of proximal
promoter sequences for RNA polymerase II with experimentally determined
transcription start site(s), TSS, from various plant species
Promoter Database of Saccharomyces cerevisiae (SCPD) Yeast Promoter Database
C. elegans promoter database (CEPDB) C. elegans Promoter Database
The Liver Specific Gene Promoter Database promoter regions responsible for liver specific transcriptions, experimentally verified regulatory regions and elements.
Regulatory Polymorphisms
rSNP_Guide System of databases documenting the influence of mutations in regulatory gene regions onto DNA interaction with nuclear proteins.
Human Gene Mutation Database (HGMD) published gene lesions responsible for human inherited disease (including regulatory mutations)
dbQSNP Accumulates and presents experimental data of sequences and allele frequencies of SNPs in the promoter regions
PromoLign Promolign provides graphical presentation for SNPs and transcription factor binding sites in the promoter region of genes in the context of human-mouse orthologous sequence alignment
Regulatory Haplotypes
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Questions or comments to oreganno@bcgsc.ca. (Archived here)